What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Glyxambi (Empagliflozin/Linagliptin)


Glyxambi (Empagliflozin/Linagliptin)

Prescription Required

10mg / 5mg
25mg / 5mg

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  • Product Details


    Your doctor may prescribe Glyxambi if you have type 2 diabetes mellitus. Glyxambi should not be prescribed for people with type 1 diabetes mellitus.

    Type 2 diabetes is a chronic condition where a person does not have enough insulin to meet their metabolic needs. This can happen through a combination of insulin resistance and decreased pancreatic function.


    Take one tablet by mouth once daily. Glyxambi is available in 10/5 mg and 25/5 mg formulations.

    Glyxambi can be taken with or without food. It should be taken at the same time every day.


    The active ingredients in Glyxambi are empagliflozin and linagliptin.

    Empagliflozin works by increasing the amount of glucose excreted through the urine.

    Linagliptin works by causing the body to release more insulin and decreasing the amount of glucose that the liver makes.


    Potential drug-drug interactions with this medication can include:

    • Apalutamide
    • Carbamazepine
    • Enzalutamide
    • Fosphenytoin
    • Lumacaftor
    • Lumacaftor-ivacaftor
    • Mitotane
    • Phenobarbital
    • Phenytoin
    • Primidone
    • Rifampin (rifampicin)
    • Insulins
    • Carbamazepine 
    • Clotrimazole 
    • Dexamethasone 
    • Fosamprenavir 
    • Indinavir 
    • Morphine 
    • Nelfinavir 
    • Phenobarbital 
    • Phenothiazines 
    • Phenytoin 
    • Prazosin 
    • Retinoic acid
    • Rifampin 
    • Ritonavir 
    • Saquinavir 
    • St. John's Wort
    • Spironolactone 
    • Tipranavir 
    • Sulfonylureas

    Tell your doctor and pharmacist if you are taking any of the above medications before starting Glyxambi.


    Use caution if you have a history of pancreatitis.

    Tell your doctor if you have a history of kidney or liver problems.

    Tell your doctor if you have a history of low blood pressure before starting this medication.

    This drug can increase the risk of urinary tract infections and yeast infections.

    Side Effects

    Common Glyxambi side effects may include:

    • Acute kidney injury
    • Bullous pemphigoid
    • Fournier's gangrene
    • Hypoglycemia
    • Increased hematocrit
    • Increased serum cholesterol
    • Nasopharyngitis
    • Rhabdomyolysis
    • Severe arthralgia
    • Skin rash
    • Upper respiratory tract infection
    • Urinary tract infection


    1. Glyxambi [package insert]. Indianapolis, IN: Eli Lilly and Company; 2015.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13224

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