Description
Your doctor may prescribe Glyxambi if you have type 2 diabetes mellitus. Glyxambi should not be prescribed for people with type 1 diabetes mellitus.
Type 2 diabetes is a chronic condition where a person does not have enough insulin to meet their metabolic needs. This can happen through a combination of insulin resistance and decreased pancreatic function.
Directions
Take one tablet by mouth once daily. Glyxambi is available in 10/5 mg and 25/5 mg formulations.
Glyxambi can be taken with or without food. It should be taken at the same time every day.
Ingredients
The active ingredients in Glyxambi are empagliflozin and linagliptin.
Empagliflozin works by increasing the amount of glucose excreted through the urine.
Linagliptin works by causing the body to release more insulin and decreasing the amount of glucose that the liver makes.
Interactions
Potential drug-drug interactions with this medication can include:
- Apalutamide
- Carbamazepine
- Enzalutamide
- Fosphenytoin
- Lumacaftor
- Lumacaftor-ivacaftor
- Mitotane
- Phenobarbital
- Phenytoin
- Primidone
- Rifampin (rifampicin)
- Insulins
- Carbamazepine
- Clotrimazole
- Dexamethasone
- Fosamprenavir
- Indinavir
- Morphine
- Nelfinavir
- Phenobarbital
- Phenothiazines
- Phenytoin
- Prazosin
- Retinoic acid
- Rifampin
- Ritonavir
- Saquinavir
- St. John's Wort
- Spironolactone
- Tipranavir
- Sulfonylureas
Tell your doctor and pharmacist if you are taking any of the above medications before starting Glyxambi.
Cautions
Use caution if you have a history of pancreatitis.
Tell your doctor if you have a history of kidney or liver problems.
Tell your doctor if you have a history of low blood pressure before starting this medication.
This drug can increase the risk of urinary tract infections and yeast infections.
Side Effects
Common Glyxambi side effects may include:
- Acute kidney injury
- Bullous pemphigoid
- Fournier's gangrene
- Hypoglycemia
- Increased hematocrit
- Increased serum cholesterol
- Nasopharyngitis
- Rhabdomyolysis
- Severe arthralgia
- Skin rash
- Upper respiratory tract infection
- Urinary tract infection
References
- Glyxambi [package insert]. Indianapolis, IN: Eli Lilly and Company; 2015.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13224