What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Gonal F Prefilled Pen with Needles

Also Known as Puregon


Gonal F Prefilled Pen with Needles

Prescription Required

300IU / 0.5ml Prefilled Pen
450IU / 0.75ml Prefilled Pen
900IU / 1.5ml Prefilled Pen

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  • Product Details


    GONAL-F is a prescription medication used to treat infertility in both men and women. It contains follitropin alfa, a recombinant follicle-stimulating hormone (FSH) that stimulates the growth and maturation of eggs in women and sperm in men.

    GONAL-F is available in a sterile, premixed injection and is administered by injection under the skin.

    Fact Table




    US FDA



    Legal status


    Chemical Name

    Follitropin alfa

    Elimination half-life

    53 hours

    Dosage (Strength)

    300IU / 0.5ml Prefilled Pen, 450IU / 0.75ml Prefilled Pen, 900IU / 1.5ml Prefilled Pen





    Protein binding

    Not available

    PubChem CID

    Not available


    Not available


    Not Available

    ATC code






    Routes of administration



    Before using GONAL-F, your doctor will provide you with specific instructions on how to administer the medication.

    The dosage schedule of GONAL-F is individualized. Take it exactly as directed by your doctor. The dosage is also individualized.

    It is important to keep track of the days and times of injections to ensure consistent dosing and avoid missed doses.


    The active ingredient in GONAL-F is follitropin alfa, which is produced using recombinant DNA technology.


    • There are no known significant interactions.


    It is important to inform your doctor if you have a history of blood clots, heart disease, liver or kidney disease, or any other medical condition before starting GONAL-F.

    Pregnant or breastfeeding women should not use GONAL-F, as it may harm the developing fetus or nursing baby. If you are taking GONAL-F for fertility, tell your doctor immediately if you become pregnant.

    Side Effects

    The most common side effects of GONAL-F may include the following:

    • Abdominal pain
    • Acne vulgaris
    • Acute respiratory distress syndrome
    • Anaphylaxis
    • Asthma
    • Atelectasis
    • Bruising at the injection site
    • Decreased libido
    • Diarrhea
    • Enlargement of abdomen
    • Fatigue
    • Flatulence
    • Gynecomastia
    • Headache
    • Hypersensitivity reaction
    • Inflammation at the injection site
    • Injection site reaction
    • Intermenstrual bleeding
    • Nausea
    • Nonimmune anaphylaxis
    • Ovarian cyst
    • Ovarian hyperstimulation syndrome
    • Ovarian neoplasm
    • Ovarian torsion
    • Ovary enlargement
    • Pain
    • Pain at the injection site
    • Pelvic discomfort
    • Pelvic pain
    • Seborrhea
    • Swelling at the injection site
    • Thromboembolism


    Gonal-F [package insert]. Rockland, MA: EMD Serono, Inc; 2020.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 9752

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