What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Grifulvin V (Griseofulvin)

Also Known as Grisovin

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Generic

What is a Generic?

Generic Equivalent - Grifulvin V (Griseofulvin)

Prescription Required

Strength
Qty
500mg

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  • Product Details

    Description

    Grifulvin V is a prescription medication used to treat dermatophyte infections, a type of fungal infection of the skin. Other terms for this condition include dermatophytosis or tinea, which affect the nails, hair, and skin.

    Symptoms of dermatophyte infection depend on where they are located and can include rashes, scaling, and itching.

    Grifulvin V works by stopping the growth and replication of fungal cells. Grifulvin V also binds to keratin in human skin, making it resistant to fungal infection.

    Fact Table

    Formula

    C17H17ClO6

    License

    US FDA

    Bioavailability

    25 to 70%

    Legal status

    Rx-Only

    Chemical Name

    Griseofulvin

    Elimination half-life

    9–21 hours

    Dosage (Strength)

    500mg

    Pregnancy

    Consult Doctor

    Brands

    Gris-peg, Grifulvin V

    Protein binding

    84%

    PubChem CID

    441140

    MedlinePlus

    a682295

    ChEBI

    27779

    ATC code

    D01AA08

    DrugBank

    DB00400

    KEGG

    D00209

    Routes of administration

    By mouth

    Directions

    The standard dosage is 500 mg in single or divided doses. Your doctor may increase the dose to 750-1000 mg per day if needed for widespread infections.

    Ingredients

    The active ingredient and name for Grifulvin V generic is griseofulvin.

    Interactions

    Common drug-drug interactions with this medication may include:

    • Alcohol 
    • Aminolevulinic Acid
    • Barbiturates
    • Carbocisteine
    • Cyclosporine
    • Hormonal contraceptives
    • Saccharomyces boulardii
    • Warfarin


    Tell your healthcare team if you are taking any of the above medications before starting Grifulvin V.

    Cautions

    Tell your doctor if you have a history of blood disorders. Grifulvin V has been rarely reported to cause leukopenia.

    Use caution if you have a history of liver problems before taking this medication.

    If you have a history of allergic reactions to penicillin, use caution before taking Grifulvin V.

    Wear sunscreen while taking this medication because it can increase the sensitivity to the sun.

    Call your doctor immediately if you have a skin reaction after starting this drug.

    Side Effects

    Grifulvin V side effects may include:

    • Angioedema
    • Confusion
    • Dermatologic reaction
    • Diarrhea
    • Dizziness
    • Epigastric distress
    • Fatigue
    • Gastrointestinal hemorrhage
    • Granulocytopenia
    • Headache
    • Hepatotoxicity
    • Increased liver enzymes
    • Increased serum bilirubin
    • Insomnia
    • Nausea
    • Nephrosis
    • Oral candidiasis
    • Paresthesia
    • Skin photosensitivity
    • Skin rash
    • Toxic epidermal necrolysis
    • Urticaria
    • Vomiting

    References

    1. Grifulvin V [package insert]. Los Angeles, CA: Ortho Dermatologics; 2011.

    Dr Conor Sheehy
    About Dr. Conor Sheehy (Page Author)

    Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2769

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