Hulio (Adalimumab)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Prescription Required

  • Product Details


    Hulio is used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult crohn's disease, ulcerative colitis, and plaque psoriasis.

    Hulio comes in a 40 mg/0.8 mL single-dose prefilled pen for injection. It also comes in a prefilled plastic syringe for injection in the following strengths:

    • 40 mg/0.8 mL
    • 20 mg/0.4 mL

    Fact Table




    US DailyMed and EMA


    64% (subcutaneous), 0% (by mouth)

    Legal status


    Chemical Name


    Elimination half-life

    10–20 days

    Dosage (Strength)

    40 mg/0.8 mL, 20 mg/0.4 mL


    Consult doctor



    Protein binding

    Not Available

    PubChem CID

    Not Assigned




    Not Assigned

    ATC code






    Routes of administration



    Carefully read the instructions that come with your Hulio prescription. Use Hulio as your doctor has prescribed. If you have any questions or concerns, talk to your doctor or pharmacist.

    Each dose is individualized based on the condition being treated. If Hulio is being used to treat juvenile arthritis, the dose is also based on the weight of the patient.

    Your healthcare provider will teach you how to inject Hulio and how often. Do not inject Hulio yourself until your healthcare provider has taught you how to properly do so. 


    Adalimumab-fkjp, a tumor necrosis factor (TNF) blocker, is the active ingredient contained in Hulio.

    Inactive ingredients include methionine, monosodium glutamate, polysorbate 80, sorbitol, and Water for Injection, USP. Hydrochloric acid is also an additional ingredient for pH balance. 


    No known contraindications.


    Hulio has FDA Boxed Warnings regarding the increased risk of serious infections that can lead to hospitalization or death. In addition, there is a FDA Boxed Warning regarding the risk of lymphoma and other malignancies that can be fatal with the use of TNF blockers, including adalimumab products.

    • Before you start using Hulio, inform your doctor of the following:
      • All the medications you use
      • Your allergies
      • Your health history and current health problems
      • If you are pregnant or breastfeeding
    • Serious allergic reactions, including anaphylaxis, may occur with the use of Hulio. Seek emergency care right away if you have trouble breathing, a rash, swelling of your lips, tongue, or throat, or other signs and symptoms of a serious reaction.
    • Hulio may cause reactivation of hepatitis B virus in patients who are carriers of the virus.
    • Hulio may worsen multiple sclerosis, optic neuritis, or Guillain-Barré syndrome.
    • Abnormal blood cell counts can occur with the use of Hulio. Seek medical care immediately if you develop signs and symptoms of blood disorders or infection, including fever, bruising, bleeding, or pale appearance of the skin.
    • Heart failure can occur with the use of Hulio. Seek medical care immediately if you have trouble breathing, swelling, or rapid weight gain.
    • Lupus-like syndrome can occur with the use of Hulio.
    • Live vaccines are not recommended in patients taking Hulio.

    Side Effects

    Hulio (adalimumab) side effects include infections, injection site reactions, headache, and rash. These are not all the side effects that can occur; therefore, you should contact your doctor right away if you have side effects that are concerning or persistent.


    1. Hulio (adalimumab-fkjp) injection, for subcutaneous use. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2020.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13700

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