What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Humatin (Paromomycin)


Humatin (Paromomycin)

Prescription Required


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  • Product Details


    Humatin (paromomycin) is an antibiotic drug used to treat amoebic infections of the intestine. It can also be used to treat a condition called hepatic coma. Humatin comes as a 250mg capsule that should be stored at room temperature.


    • Take Humatin 250mg capsules with food.
    • You should finish your entire prescription, even if you feel better.
    • If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses at the same time.
    • Humatin dosage:
      • Intestinal amebiasis: The usual dose for adults and children is 25 to 30mg/kg of body weight daily. Your doctor will divide your total daily dosage into three doses per day.  Treatment can last from five to ten days.
      • Management of hepatic coma: The usual dose is 4000mg per day. Your doctor will divide your daily dosage into multiple doses taken at regular intervals.  Treatment can last for five to six days.


    The active ingredient of Humatin is paromomycin. A full list of inactive ingredients can be found in the package insert.

    Fact Table




    US FDA


    Poorly absorbed in the GI tract

    Legal status

    US: RX Only

    Chemical Name


    Elimination half-life


    Dosage (Strength)

    250mg (16 Capsules)


    Consult a doctor



    Protein binding


    PubChem CID






    ATC code

    A07AA06, QJ01GB92





    Routes of administration

    By mouth, intramuscular, topical


    • You should not use Humatin if you are allergic to paromomycin or any of the ingredients listed in the package insert.
    • Do not use Humatin if you have an obstruction in your bowels.
    • You should use Humatin cautiously if you have any bowel lesions. Discuss the risks with your physician.
    • Watch for signs and symptoms of infections while using Humatin. Click here to learn more.

    Side Effects

    The side effects of Humatin can include:

    • Nausea
    • Abdominal Cramps
    • Diarrhea

    Other Considerations

    • Consult with a physician before you buy Humatin.


    1. Humatin (Paromomycin Sulfate Capsules): USES, Dosage, side effects, interactions, warning. (2016, June 13). Retrieved March 20, 2020
    2. DailyMed - paromomycin SULFATE capsule. (2018). Retrieved March 20, 2020
    3. Humatin (paromomycin sulfate) Capsule. (n.d.). Retrieved March 19, 2020

    Frequently Asked Questions about Humatin (Paromomycin)

    What is Humatin (Paromomycin)?

    Humatin (Paromomycin) is a prescription medication used to treat intestinal amebiasis and hepatic coma. Amebiasis is a disease caused by a parasite that infects the intestines. Hepatic coma is a life-threatening condition that can occur in people with severe liver disease.

    What is Humatin used for?

    Humatin is used to:
    - Treat acute and chronic intestinal amebiasis, including asymptomatic carriers
    - Manage hepatic coma as an adjunctive therapy

    How does Humatin work?

    Humatin is an aminoglycoside antibiotic that works by killing bacteria and parasites. It kills bacteria by preventing them from making proteins that they need to survive. It kills parasites by disrupting their cell membranes.

    What is the dosage for Humatin?

    The dosage of Humatin varies depending on the condition being treated. For intestinal amebiasis, the recommended dosage for adults is 25-35 mg/kg/day divided into three doses. For hepatic coma, the recommended dosage for adults is 4 g/day divided into four doses.

    How to take Humatin?

    Humatin capsules should be taken with food or water. Swallow the capsules whole. Do not crush, chew, or break the capsules.

    What are the side effects of Humatin?

    The most common side effects of Humatin are nausea, vomiting, diarrhea, and abdominal pain. Other possible side effects include headache, dizziness, rash, and hearing loss.

    Who should not take Humatin?

    You should not take Humatin if you are allergic to paromomycin or any of the other ingredients in the medication. You should also not take Humatin if you have severe kidney disease or severe liver disease.

    Can I take Humatin while pregnant or breastfeeding?

    Talk to your doctor about the risks and benefits of taking Humatin while pregnant or breastfeeding. Paromomycin may pass into breast milk, but it is not known if it is harmful to a nursing infant.

    What are the drug interactions with Humatin?

    Humatin may interact with other medications you are taking, such as digoxin, aminoglycoside antibiotics, and diuretics. Talk to your doctor about any other medications you are taking before starting Humatin.

    How long can I take Humatin?

    The length of time you need to take Humatin depends on the condition being treated. For intestinal amebiasis, the usual course of treatment is 5-10 days. For hepatic coma, the usual course of treatment is 5-6 days.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2782

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