What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Incruse Ellipta (Umeclidinium)

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Brand

Incruse Ellipta (Umeclidinium)

Prescription Required

Strength
Qty
55mcg (62.5mcg) (30 doses / inhaler)

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  • Product Details

    Description

    Incruse Ellipta is an inhaled medication that is used to treat Chronic Obstructive Pulmonary Disease (COPD). COPD is a group of chronic diseases that includes chronic bronchitis and emphysema.

    The symptoms of COPD are progressive and can include shortness of breath, chronic cough, and wheezing.

    Incruse Ellipta works by stopping acetylcholine, a neurotransmitter, from activating muscarinic receptors in the smooth muscle of the lungs. This effect causes bronchodilation, which is the relaxation of the airways, and makes it easier to breathe.

    Fact Table

    Formula

    C29H34BrNO2

    License

    EU EMA

    Bioavailability

    13%

    Legal status

    Rx-only

    Chemical Name

    Umeclidinium

    Elimination half-life

    11 hours

    Dosage (Strength)

    55mcg

    Pregnancy

    Consult Doctor

    Brands

    Incruse Ellipta

    Protein binding

    ~89%

    PubChem CID

    11519069

    MedlinePlus

    a614024

    ChEBI

    79040

    ATC code

    R03BB07

    DrugBank

    DB09076

    KEGG

    D10181

    Routes of administration

    Inhalation

    Directions

    The standard dosage of Incruse Ellipta inhaler is one inhalation once daily.

    Incruse Ellipta is a maintenance medication, meaning it must be taken every day to be effective.

    Ingredients

    The active ingredient in Incruse Ellipta is called umeclidinium.

    Interactions

    • Aclidinium
    • Amantadine
    • Atropine
    • Benztropine
    • Botulinum Toxin-Containing Products
    • Chloral Betaine
    • Chlorthalidone
    • Darifenacin
    • Dicyclomine
    • Fesoterodine
    • Gastrointestinal Agents
    • Glucagon
    • Glycopyrrolate
    • Hydrochlorothiazide
    • Hyoscyamine
    • Ipratropium
    • Mirabegron
    • Nitroglycerin
    • Oxybutynin
    • Potassium Chloride
    • Scopolamine
    • Solifenacin
    • Tiotropium
    • Tolterodine
    • Topiramate
    • Trihexyphenidyl
    • Trospium

    Cautions

    Do not use Incruse Ellipta if you have an allergy to milk proteins.

    Incruse Ellipta cannot be used to treat acute symptoms of COPD or for acutely worsening patients. Acute symptoms should be treated with a rescue inhaler like albuterol.

    Tell your doctor if you have a history of narrow-angle glaucoma before starting this medication.

    Incruse Ellipta can worsen urinary retention in some people.

    Side Effects

    Every medication has a list of potential side effects. Common Incruse Ellipta side effects can include:

    • Arthralgia
    • Blurred vision
    • Bruise
    • Cough
    • Dysgeusia
    • Dysuria
    • Eye pain
    • Glaucoma
    • Myalgia
    • Nasopharyngitis
    • Pharyngitis
    • Tachycardia
    • Toothache
    • Upper abdominal pain
    • Upper respiratory infection
    • Urinary retention
    • Viral upper respiratory tract infection


    Speak with your doctor and pharmacist about any side effects you experience while using this inhaler.

    References

    1. Incruse Ellipta [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2016.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13204

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