What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Indayo (Levonorgestrel / Ethinyl Estradiol)

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Generic Equivalent - Indayo (Levonorgestrel / Ethinyl Estradiol)

Prescription Required

Strength
Qty
0.15mg/0.03mg

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  • Product Details

    Description

    Indayo is a prescription oral contraceptive product for birth control, menstrual suppression, abnormal uterine bleeding, and other indications.


    Fact Table

    Formula

    C21H28O2, C20H24O2

    License

    US DailyMed, US FDA, EU EMA

    Bioavailability

    38% - 48%

    Legal status

    Rx-Only

    Chemical Name

    Levonogestrel and Ethinyl Estradiol

    Elimination half-life

    7–36 hours

    Dosage (Strength)

    120mcg/30mcg

    Pregnancy

    -

    Brands

    Indayo

    Protein binding

    97–98%

    PubChem CID

    13109, 5991

    MedlinePlus

    a610021, a604032

    ChEBI

    6443, 4903

    ATC code

    G03AC03, G03CA01

    DrugBank

    DB00367

    KEGG

    D00950, D00554

    Routes of administration

    By mouth

    Directions

    Take one tablet by mouth once daily with or without food. The tablet should be taken at the same time every day.

    Ingredients

    The active ingredients are levonorgestrel and ethinyl estradiol.

    Interactions

    Drug-drug interactions may include:

    • Ajmaline
    • Anastrozole
    • Anthrax Immune Globulin (Human)
    • Antidiabetic Agents
    • Aprepitant
    • Asparaginase Products
    • Atazanavir
    • Bile Acid Sequestrants
    • Brigatinib
    • C1 inhibitors
    • Carfilzomib
    • Ivosidenib
    • Ixazomib
    • LamoTRIgine
    • Lenalidomide
    • Lixisenatide
    • Lomitapide
    • Mavacamten
    • Melatonin
    • MetyraPONE
    • MiFEPRIStone
    • Mivacurium
    • Mobocertinib
    • Mycophenolate
    • Nirmatrelvir and Ritonavir
    • Nonsteroidal Anti-Inflammatory Agents (COX-2 Selective)
    • Octreotide

    Cautions

    Tell your doctors if you have a history of heart disease, liver problems, breast cancer, ovarian cancer, or are a current smoker.

    Ask your pharmacist or doctor about all precautions that apply to you.

    Side Effects

    Common side effects may include:

    • Abdominal cramps
    • Abdominal pain
    • Abnormal cervical or vaginal Papanicolaou smear
    • Acne vulgaris
    • Acute myocardial infarction
    • Allergic skin rash
    • Amenorrhea
    • Application site reaction
    • Arterial thromboembolism
    • Auditory disturbance
    • Bloating
    • Breakthrough bleeding
    • Breast changes
    • Budd-Chiari syndrome
    • Cataract
    • Cerebral hemorrhage
    • Cerebral thrombosis
    • Cerebrovascular accident
    • Cervical ectropion
    • Cervical erosion
    • Change in appetite
    • Change in cervical secretions
    • Change in corneal curvature
    • Change in libido
    • Change in menstrual flow
    • Changes in serum lipids
    • Chloasma
    • Cholecystitis
    • Cholelithiasis
    • Cholestatic jaundice
    • Colitis
    • Contact lens intolerance
    • Cystitis-like syndrome
    • Decreased serum folate level
    • Deep vein thrombosis
    • Depression
    • Dizziness
    • Dysmenorrhea
    • Ectopic pregnancy
    • Edema
    • Endocervical hyperplasia
    • Erythema multiforme
    • Erythema nodosum
    • Exacerbation of porphyria
    • Exacerbation of systemic lupus erythematosus
    • Exacerbation of tics
    • Fluid retention
    • Gallbladder disease
    • Headache
    • Hemolytic-uremic syndrome
    • Hemorrhagic eruption
    • Hepatic adenoma
    • Hepatic focal nodular hyperplasia
    • Hepatic neoplasm (benign)
    • Hirsutism
    • Hypertension
    • Impaired glucose tolerance/prediabetes
    • Infertility (temporary)
    • Infrequent uterine bleeding
    • Lactation insufficiency (with use immediately postpartum)
    • Local thrombophlebitis
    • Loss of scalp hair
    • Major depressive disorder
    • Mesenteric thrombosis
    • Migraine
    • Mood changes
    • Nausea
    • Nervousness
    • Nonimmune anaphylaxis
    • Optic neuritis
    • Pancreatitis
    • Premenstrual syndrome
    • Pulmonary embolism
    • Renal insufficiency
    • Retinal thrombosis
    • Rhinitis
    • Spotting
    • Suicidal ideation
    • Uterine fibroid enlargement
    • Vaginitis
    • Venous thromboembolism
    • Venous thrombosis
    • Vomiting
    • Vulvovaginal candidiasis
    • Weight changes
    • Weight gain
    • Worsening of varicose veins

    References

    1. Indayo [Product Monograph]. Etobicoke, ON: Mylan Pharmaceuticals; 2016.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13909

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