What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Intrarosa (Prasterone)


Intrarosa (Prasterone)

Prescription Required


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  • Product Details


    INTRAROSA (Prasterone) is an intravaginal medication that can be prescribed to treat dyspareunia during menopause. 

    Dyspareunia is a symptom of menopause that includes pain during intercourse or during other sexual activities that include penetration. The pain may be located in different parts of the vagina.

    INTRAROSA is a topical steroid product. It isn't active but the body converts it to active estrogens and androgens when applied topically. These active steroids help to ease pain experienced during intercourse and treat dyspareunia.


    The normal INTRAROSA dosage is 6.5 mg per vaginal insert.

    Insert one vaginal insert intravaginally once per day using the included applicator.


    The active ingredient in INTRAROSA is prasterone. Inactive ingredients include Witepsol (off-white hard fat).

    Fact Table







    Legal status

    US: Over the counter, CAD: Schedule IV

    Chemical Name


    Elimination half-life

    DHEA: 25 minutes, DHEA-S: 11 hours

    Dosage (Strength)

    6.5mg (28 inserts)


    Consult a doctor



    Protein binding


    PubChem CID






    ATC code

    G03XX01, G03EA03Q, A14AA07





    Routes of administration



    INTRAROSA has no known drug-drug interactions.


    Tell your healthcare provider if you or your family has a history of breast cancer.

    INTRAROSA should not be used by those with abnormal genital bleeding.

    Side Effects

    INTRAROSA has been shown to have the following adverse reactions:

    • Abnormal pap smear
    • Vaginal discharge


    Intrarosa [package insert].Quebec City, Canada: Endoceutics; 2016.

    Frequently Asked Questions about Intrarosa

    What is Intrarosa?

    Intrarosa is a prescription medication containing the active ingredient Prasterone, which is a form of the hormone dehydroepiandrosterone (DHEA). It is used to treat women experiencing moderate to severe pain during sexual intercourse, a symptom of vulvar and vaginal atrophy (VVA) due to menopause.

    How is Intrarosa administered?

    Intrarosa is a vaginal insert that is administered once daily at bedtime, using the provided applicator.

    How does Intrarosa work?

    Once inserted into the vagina, Prasterone is converted into estrogen and androgen, hormones that are naturally present in the body. These hormones help restore and maintain the health and elasticity of vaginal tissues.

    What are the potential side effects of Intrarosa?

    Common side effects may include vaginal discharge, abnormal Pap smear results, and hot flushes. It's important to consult with your healthcare provider about any side effects or concerns.

    Can I use Intrarosa if I'm pregnant or breastfeeding?

    Intrarosa is not intended for use in women who are pregnant or breastfeeding. If you become pregnant while using Intrarosa, discontinue use and contact your healthcare provider.

    How should I store Intrarosa?

    Store Intrarosa at room temperature, away from moisture and heat. Keep it out of reach of children.

    Can I use Intrarosa with other vaginal products?

    It's essential to inform your healthcare provider about all the products you're using, including over-the-counter products. They can provide guidance on whether it's safe to use Intrarosa in conjunction with other products.

    How long does it take for Intrarosa to work?

    The time it takes for Intrarosa to show its effects can vary among individuals. It's essential to follow your healthcare provider's instructions and continue using the medication as prescribed.

    Are there any contraindications for using Intrarosa?

    Women with undiagnosed abnormal vaginal bleeding or those who have or have had certain types of cancers should not use Intrarosa. Always consult with your healthcare provider before starting any new medication.

    How can I get a prescription for Intrarosa?

    If you believe you may benefit from Intrarosa, consult with your healthcare provider. They can evaluate your symptoms and determine if Intrarosa is right for you.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13268

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