Description
INTRAROSA (Prasterone) is an intravaginal medication that can be prescribed to treat dyspareunia during menopause.
Dyspareunia is a symptom of menopause that includes pain during intercourse or during other sexual activities that include penetration. The pain may be located in different parts of the vagina.
INTRAROSA is a topical steroid product. It isn't active but the body converts it to active estrogens and androgens when applied topically. These active steroids help to ease pain experienced during intercourse and treat dyspareunia.
Directions
The normal INTRAROSA dosage is 6.5 mg per vaginal insert.
Insert one vaginal insert intravaginally once per day using the included applicator.
Ingredients
The active ingredient in INTRAROSA is prasterone. Inactive ingredients include Witepsol (off-white hard fat).
Fact Table |
Formula |
C19H28O2 |
License |
- |
Bioavailability |
50% |
Legal status |
US: Over the counter, CAD: Schedule IV |
Chemical Name |
Prasterone |
Elimination half-life |
DHEA: 25 minutes, DHEA-S: 11 hours |
Dosage (Strength) |
6.5mg (28 inserts) |
Pregnancy |
Consult a doctor |
Brands |
Intrarosa |
Protein binding |
- |
PubChem CID |
5881 |
MedlinePlus |
a617012 |
ChEBI |
- |
ATC code |
G03XX01, G03EA03Q, A14AA07 |
DrugBank |
DB01708 |
KEGG |
D08409 |
Routes of administration |
Insert |
Interactions
INTRAROSA has no known drug-drug interactions.
Cautions
Tell your healthcare provider if you or your family has a history of breast cancer.
INTRAROSA should not be used by those with abnormal genital bleeding.
Side Effects
INTRAROSA has been shown to have the following adverse reactions:
- Abnormal pap smear
- Vaginal discharge
References
Intrarosa [package insert].Quebec City, Canada: Endoceutics; 2016.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13268