What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Intuniv (Guanfacine HCL)

Sezzle
Brand

Intuniv (Guanfacine HCL)

Prescription Required

Strength
Qty
1mg
2mg
3mg
4mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

Generic Equivalent - Intuniv (Guanfacine HCL)

Prescription Required

Strength
Qty
1mg
2mg
3mg
4mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details

    Description

    Intuniv is a prescription medication used for Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6-17 years. It is typically used in patients that have failed stimulant medications or in whom stimulants would not be a good choice.

    ADHD is a chronic condition that affects children, adolescents, and adults. Symptoms may include self-focused behavior, interruptions, fidgeting, unfinished tasks, and others.

    Intuniv medicine works by activating alpha receptors in the nervous system, which causes a reduction in certain nerves that slows the heart rate and ADHD-type behaviors.

    Fact Table

    Formula

    C9H9Cl2N3O

    License

    US FDA, EU EMA

    Bioavailability

    80–100%

    Legal status

    Rx-only

    Chemical Name

    Guanfacine

    Elimination half-life

    10-17 hours

    Dosage (Strength)

    1 mg to 4 mg

    Pregnancy

    No Known Risk

    Brands

    Estulic, Intuniv

    Protein binding

    70%

    PubChem CID

    3519

    MedlinePlus

    a601059

    ChEBI

    5558

    ATC code

    C02AC02

    DrugBank

    DB01018

    KEGG

    D08031

    Routes of administration

    By mouth

    Directions

    The dosage for this medication is specific to each patient based on weight. The correct dosage should be determined by the prescriber and should not be adjusted without their direction.

    Ingredients

    The active ingredient in Intuniv is guanfacine. It is available in Intuniv 1 mg, 2 mg, 3 mg, and 4 mg.

    Interactions

    Do not take Intuniv with the following medications unless directed to do so by your physician: 

    • Alcohol 
    • Amifostine
    • Amiodarone
    • Apalutamide
    • Aprepitant
    • Azelastine 
    • Berotralstat
    • Beta-Blockers
    • Bromperidol
    • Buprenorphine
    • Carbamazepine
    • Ceritinib
    • Cimetidine
    • Conivaptan
    • Crizotinib
    • Cyclosporine
    • Diltiazem
    • Dronedarone
    • Duvelisib
    • Enzalutamide
    • Erythromycin
    • Fedratinib
    • Fluconazole
    • Flunitrazepam
    • Fosamprenavir
    • Fosaprepitant
    • Fosnetupitant-palonosetron
    • Fosphenytoin
    • Fusidic Acid (Systemic)
    • Grapefruit juice
    • Imatinib
    • Isavuconazole
    • Lefamulin
    • Letermovir
    • Lumacaftor
    • Lumacaftor-ivacaftor
    • Mirtazapine
    • Mitotane
    • Netupitant
    • Nilotinib
    • Obinutuzumab
    • Orphenadrine
    • Oxomemazine
    • Oxycodone
    • Phenobarbital
    • Phenytoin
    • Primidone
    • Ribociclib
    • Rifampin (rifampicin)
    • Schisandra
    • Thalidomide
    • Tricyclic Antidepressants
    • Verapamil

    Cautions

    Intuniv may slow the heart rate, especially when starting it.

    Intuniv can cause sleepiness and drowsiness.

    Your doctor should monitor blood pressure when starting this medication.

    Side Effects

    The most common side effects can include:

    • Drowsiness 
    • Abdominal pain
    • Agitation
    • Anxiety
    • Bradycardia
    • Constipation
    • Decreased appetite
    • Depression
    • Diarrhea
    • Dizziness
    • Emotional lability
    • Fatigue
    • First-degree AV block
    • Headache
    • Hypotension
    • Increased blood pressure
    • Insomnia
    • Irritability
    • Lethargy
    • Loss of consciousness
    • Nausea
    • Nightmares
    • Orthostatic hypotension
    • Pruritus
    • Sinus arrhythmia
    • Skin rash
    • Syncope
    • Tachycardia
    • Vomiting
    • Weight gain
    • Xerostomia

    References

    1. Intuniv [package insert]. Lexington, MA: Shire; 2017.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 12188

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