A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Invokamet is made up of two medications, canagliflozin and metformin hydrochloride. It's used with diet and exercise to treat adults with type 2 diabetes. Canagliflozin is used to decrease the risk of serious cardiovascular events in adults with type 2 diabetes and heart disease and the risk of end-stage kidney disease, doubling serum creatinine levels, death caused by cardiovascular reasons, and hospitalization for adults with type 2 diabetes, heart failure, and diabetic kidney disease with the presence of albumin in the urine.
Invokamet should not be used to treat adults with type 1 diabetes as this may increase their risk for a serious condition called diabetic ketoacidosis.
Follow your doctor's instructions and read the information that comes with your Invokamet prescription. Don't hesitate to reach out to your doctor or pharmacist with any questions or concerns you have.
Invokamet oral tablets are available in the following strengths:
The recommended starting dose is Invokamet (canagliflozin 50 mg and metformin 500 mg) by mouth two times a day with meals. The dose may be adjusted based on kidney function and response to the medication.
Each Invokamet tablet contains canagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide. Inactive ingredients include croscarmellose sodium, hypromellose, magnesium stearate, and microcrystalline cellulose. The film-coating is made of macrogol/PEG3350, polyvinyl alcohol (hydrolyzed partially), talc, titanium dioxide, iron oxide yellow (50 mg/1,000 mg and 150 mg/500 mg tablets), iron oxide red (50 mg/1,000 mg, 150 mg/500 mg, and 150 mg/1,000 mg tablets), and iron oxide black (150 mg/1,000 mg tablets).
Do not take Invokamet if you have severe kidney problems or if you are on dialysis.
Do not take Invokamet if you have metabolic acidosis such as diabetic ketoacidosis.
Do not take Invokamet if you are allergic to canagliflozin, metformin, or any of the other ingredients or excipients contained in Invokamet.
WARNING: LACTIC ACIDOSIS
See full prescribing information for complete boxed warning.
Like with any medication, Invokamet can cause side effects. Although the most common Invokamet side effects are genital fungal infections in women, urinary tract infections, frequent urination, diarrhea, nausea, vomiting, gas, weakness, indigestion, stomach discomfort, and headache, they are not all the possible side effects that can occur during treatment.
Call your doctor right away if you have side effects that bother you or won't go away.
Curious about the Invokamet cost? With a valid prescription, you can buy Invokamet at a competitive cost online at Canada Pharmacy.