Description
ISOPTO CARPINE can be prescribed by healthcare professionals that treat conditions of the eye. They are useful for a variety of conditions, including:
- Induction of miosis (pupil constriction)
- Manage acute angle-closure glaucoma
- Reduce eye pressure in people with ocular hypertension or open-angle glaucoma
- Prevent increased eye pressure after laser surgery
ISOPTO CARPINE works by lowering the pressure inside of the eye. It attaches to muscarinic receptors, which causes contraction of the iris sphincter and ciliary muscle. The effects of ISOPTO CARPINE drops cause miosis and lower intraocular pressure (IOP).
Directions
Use ISOPTO CARPINE exactly as prescribed by your doctor.
The usual dose is one drop into the eye up to four times daily. ISOPTO CARPINE can be used in a single eye or both eyes.
Ingredients
The active ingredient in ISOPTO CARPINE is pilocarpine.
Fact Table |
Formula |
C11H16N2O2 |
License |
AU, US FDA |
Bioavailability |
- |
Legal status |
RX Only |
Chemical Name |
Pilocarpine |
Elimination half-life |
0.76 hours |
Dosage (Strength) |
1% Eye Drops (15mL), 2% Eye Drops (15mL), 4% Eye Drops (15mL) |
Pregnancy |
Consult a doctor |
Brands |
Betoptic Pilo, Isopto Carpine, Minims Pilocarpine Nitrate, Salagen, Vuity |
Protein binding |
- |
PubChem CID |
5910 |
MedlinePlus |
a608039 |
ChEBI |
8207 |
ATC code |
N07AX01, S01EB01 |
DrugBank |
DB01085 |
KEGG |
D00525 |
Routes of administration |
Topical eye drops |
Interactions
ISOPTO CARPINE can interact with the following medications:
- Acetylcholinesterase Inhibitors
- Beta-blockers
- Cyclopentolate
- Sincalide
Tell your doctor or pharmacist if you are taking any of the above medications.
Cautions
If you wear contact lenses, wait 15 minutes after the instillation of ISOPTO CARPINE before putting in the lenses.
Separate different eye drops by at least 5 minutes.
ISOPTO CARPINE can impair night vision. Use caution if you will be driving or operating machinery at night.
Your doctor should perform a funduscopy of the retina before prescribing this medication.
Tell your doctor if you have a history of iritis or congenital glaucoma.
Side Effects
The most common ISOPTO CARPINE side effects may include:
- Accommodative change
- Blurred vision
- Eye irritation
- Eye pain
- Headache
- Visual impairment
References
Isopto Carpine [package insert]. Fort Worth, TX: Alcon; 2010.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 11330