What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Jadenu (Deferasirox)

Sezzle
Brand

Jadenu (Deferasirox)

Prescription Required

Strength
Qty
90mg
180mg
360mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

Generic

What is a Generic?

Generic Equivalent - Jadenu (Deferasirox)

Prescription Required

Strength
Qty
90mg
180mg
360mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details

    Description

    If you have experienced high iron in your blood then you may have received a blood transfusion. After receiving the infusion of red blood cells, your healthcare team may prescribe you to buy Jadenu. Jadenu should only be prescribed by healthcare providers specially trained in the management of chelating agents.

    Symptoms of iron overload may include:

    • Abnormal heart rhythm
    • Darkening of the skin
    • Fatigue
    • Joint pain
    • Stomach pain


    Iron overload is also called hemochromatosis and is a chronic condition. If left untreated, it can damage several organs.

    Fact Table

    Formula

    C21H15N3O4

    License

    EU EMA, US FDA

    Bioavailability

    70%

    Legal status

    Rx Only

    Chemical Name

    Deferasirox

    Elimination half-life

    8 to 16 hours

    Dosage (Strength)

    90mg, 180mg, 360mg

    Pregnancy

    No known Risks

    Brands

    Exjade, Jadenu

    Protein binding

    99%

    PubChem CID

    214348

    MedlinePlus

    a606002

    ChEBI

    49005

    ATC code

    V03AC03

    DrugBank

    DB01609

    KEGG

    D03669

    Routes of administration

    By mouth

    Directions

    Take Jadenu exactly as prescribed by your doctor. Do not change the dose without speaking with them first. Your dose may be adjusted every 3-6 months based on lab readings of blood iron content.

    Ingredients

    The active ingredient in Jadenu is deferasirox, which is an iron-chelating agent. 

    Interactions

    Tell your doctor and pharmacist about all medications you are taking before you buy Jadenu and begin on this medication. It has many potential drug interactions, including:

    • Aluminum Hydroxide
    • Amodiaquine
    • Alosetron
    • Bendamustine
    • Bile Acid Sequestrants
    • Busulfan
    • Fosphenytoin
    • Phenytoin
    • Phenobarbital
    • Rasagiline
    • Ritonavir
    • Rifampin
    • Selexipag
    • Theophylline
    • Tizanidine


    Do not start any over-the-counter medications (OTC), herbals, or supplements while on Jadenu without first speaking with your healthcare team.

    Cautions

    Tell your doctor if you have a history of ear or ear disorders since Jadenu can worsen these problems. 

    Use caution if you have a history of kidney or liver problems. These effects may happen more frequently in older adults.

    Stop using Jadenu immediately if a skin rash develops or if you experience breathing difficulties.

    Your doctor should monitor your blood cells while taking this drug.

    Side Effects

    Common Jadenu side effects may include:

    • Abdominal pain
    • Acute pancreatitis
    • Anxiety
    • Cholelithiasis
    • Diarrhea
    • Dizziness
    • Duodenal ulcer
    • Dyschromia
    • Edema
    • Fanconi's Syndrome
    • Fatigue
    • Gastrointestinal hemorrhage
    • Gastritis
    • Increased liver enzymes
    • Nausea
    • Proteinuria
    • Serum creatinine increase
    • Skin rash
    • Sleep disorder
    • Vomiting

    References

    Jadenu [package insert]. East Hanover, NJ: Novartis; 2020.


    Dr Conor Sheehy
    About Dr. Conor Sheehy (Page Author)

    Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13225

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