What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Jardiance (Empagliflozin)
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Product Details
Description
JARDIANCE (empagliflozin) is a medication prescribed to treat type 2 diabetes mellitus. JARDIANCE is prescribed in combination with diet and exercise to help improve blood glucose control. JARDIANCE may also be prescribed to reduce the risk of cardiovascular death in people with both type 2 diabetes mellitus and cardiovascular disease.
JARDIANCE is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. SGLT2 is a protein on the surface of certain kidney cells. When the kidney filters blood to urine, glucose is filtered out but pulled back into the blood by SGLT2. JARDIANCE blocks SGLT2, so when glucose is filtered into the urine, it cannot be pulled back into the blood. This lowers blood glucose and helps to treat type 2 diabetes mellitus.
Fact Table
Formula
C23H27ClO7
License
EU EMA, US DailyMed
Bioavailability
78%
Legal status
Rx-Only
Chemical Name
Empagliflozin
Elimination half-life
12.4 hours
Dosage (Strength)
10mg, 25mg
Pregnancy
Not recommended
Brands
Jardiance
Protein binding
86.2%
PubChem CID
11949646
MedlinePlus
a614043
ChEBI
82720
ATC code
A10BK03
DrugBank
DB09038
KEGG
D10459
Routes of administration
By mouth (tablets)
Directions
Take 10 mg once daily with or without food. JARDIANCE should be taken in the morning.
The dose can be increased to 25 mg once daily as needed.
Ingredients
The active ingredient in JARDIANCE is empagliflozin.
Cautions
Speak with your doctor before starting JARDIANCE if you have a history of low blood pressure (hypotension) or are taking diuretics for heart or fluid conditions. JARDIANCE can change the amount of fluid in your body, potentially worsening these conditions.
JARDIANCE and similar medications have been linked to a serious condition called diabetic ketoacidosis (DKA). During DKA, the blood sugar is very high but cannot be utilized by the cells of the body, so instead, they break down fat molecules. DKA is a medical emergency and signs and symptoms can include fruit-scented breath, higher thirst, nausea and vomiting, stomach pain, weakness, and confusion.
Speak with your doctor if you have a history of kidney problems before starting JARDIANCE.
While taking JARDIANCE, you may have an increased risk of urinary tract infection. JARDIANCE and similar medications cause the kidney to excrete higher amounts of glucose, which can act as food for bacteria.
JARDIANCE may increase LDL cholesterol, so you should be monitored for changes while taking this medication.
Side Effects
The most common side effects of JARDIANCE include:
- Arthralgia
- Dyslipidemia
- Female genital mycotic infections
- Increased urination
- Male genital mycotic infections
- Nausea
- Upper respiratory tract infection
- Urinary tract infection
Buy Jardiance online from a source like Canada Pharmacy. The cost of Jardiance 10 mg and the cost of Jardiance 25 mg may be less expensive online than your local pharmacy.
References
- Jardiance. [package insert] Indianapolis, IN: Boehringer Ingelheim International; 2016.
Frequently Asked Questions about Jardiance
What is Jardiance used for?
Jardiance helps control blood sugar in type 2 diabetes and lowers heart and kidney risks.
Does Jardiance cause weight loss?
Yes, it aids weight loss in type 2 diabetes.
What happens if you take Jardiance at night?
Taking Jardiance at night may disturb your sleep due to increased urination.
What are the dangers of taking Jardiance?
Serious risks include low blood pressure, blood sugar, kidney problems, and infections.
How does Jardiance work?
Jardiance helps control blood sugar by increasing glucose removal through urine and reduces heart and kidney risks.
What drugs should not be taken with Jardiance?
Avoid if you have type 1 diabetes or severe kidney issues, but it can be used with other type 2 diabetes medications.
Can you take Jardiance if you are not diabetic?
No, it's only for managing type 2 diabetes.
How to avoid yeast infections on Jardiance?
Maintain good hygiene and follow doctor's instructions.
What happens if you miss a dose of Jardiance?
If you miss a dose, take it as soon as you remember. Skip the missed dose if it's close to the next scheduled dose. Do not double up on doses.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13178
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