What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Jorveza (Budesonide)
Prescription Required
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Product Details
Description
Jorveza (budesonide) is used to treat adults with eosinophilic esophagitis.
Jorveza is available in a 1 mg orodispersible tablet.
Fact Table
Formula
C25H34O6
License
US DailyMed, EU EMA
Bioavailability
10-20%
Legal status
Rx-Only
Chemical Name
Budesonide
Elimination half-life
2.0-3.6 hours
Dosage (Strength)
0.5mg, 1mg
Pregnancy
Consult Doctor
Brands
Jorveza
Protein binding
85-90%
PubChem CID
40000
MedlinePlus
a608007
ChEBI
3207
ATC code
A07EA06
DrugBank
DB01222
KEGG
D00246
Routes of administration
By mouth
Directions
Take Jorveza exactly as your doctor has prescribed. If you have any questions or concerns, talk to your doctor or pharmacist.
The recommended daily dose is to take one tablet in the morning and one tablet in the evening. Do not chew or swallow the undissolved tablet. Place the tablet on the tip of your tongue and gently press it against the top of your mouth. The tablet should dissolve within two minutes. Take after a meal. Do not consume food or drink or undergo oral hygiene for at least 30 minutes after taking it. Do not use oral solutions, sprays, or chewable tablets for at least 30 minutes before or after taking it.
Treatment is usually for 6 weeks.
Ingredients
The active ingredient in Jorveza is budesonide, a corticosteroid. Inactive ingredients include anhydrous monosodium citrate, disodium hydrogen citrate, docusate sodium, macrogol 6000, magnesium stearate, mannitol, povidone K25, sodium hydrogen carbonate, and sucralose.
Contraindications
Jorveza should not be used in patients who are allergic to the medication or to any of its ingredients. Jorveza should also not be used in patients with uncontrolled infections or active tuberculosis.
Cautions
- Before you start taking Jorveza (budesonide), tell your doctor:
- About all the medications you take, including prescription and nonprescription medications
- About your allergies
- About your medical history and current health problems
- If you are pregnant or breastfeeding
- Jorveza may cause hypothalamus-pituitary-adrenal axis suppression.
- Jorveza may cause systemic reactions, especially at high doses or if taken for a long period of time. Cushing’s syndrome, adrenal suppression, growth retardation, decreased bone mineral density, cataracts, glaucoma, and psychiatric/behavioral effects can occur.
- Caution should be used when patients are going from a glucocorticosteroid with higher systemic effect.
- Jorveza may not be optimally eliminated in patients with liver problems. The risk of side effects is increased in these patients; however, there is no systemic data available. Therefore, patients with liver problems should not take Jorveza.
- Jorveza can cause immune system problems and increase the risk of infections.
- Fungal infections in the mouth and throat can occur with the treatment of Jorveza.
- Chickenpox, herpes zoster, and measles can become more serious or life-threatening in patients who are taking Jorveza.
- Patients who are being treated with Jorveza should not receive live vaccinations.
- Vision problems can occur with the use of Jorveza.
- Jorveza should not be used in patients with severe kidney problems.
Side Effects
Some Jorveza side effects include gastroesophageal reflux disease, indigestion, soft feces, nausea, fungal infection in the mouth and throat, trouble sleeping, excessive urination, and high blood pressure. However, these are not all the side effects that can occur. Be sure to contact your doctor right away if you have side effects that bother you or won’t go away.
Want to pay a lower Jorveza price? With a valid prescription from your doctor, you can buy Jorveza (budesonide) online here at a competitive price.
Reference:
Jorveza. Blainville, Quebec: AVIR Pharma Inc.; 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13805
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