A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Kaletra (Ritonavir/Lopinavir)
Brand
Kaletra (Ritonavir/Lopinavir)
Prescription Required
Strength
Qty
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Product Details
Description
Kaletra is a medication your doctor may prescribe to treat human immunodeficiency virus (HIV-1). It is often given in combination with other antiviral medications.
HIV is a viral infection of the immune system. HIV viral particles attach to, enter, and destroy cells of the immune system that fight off infection.
Fact Table
Formula
C37H48N6O5S2
License
EU EMA, US FDA
Bioavailability
-
Legal status
RX Only
Chemical Name
Lopinavir/ritonavir
Elimination half-life
3-5 hours
Dosage (Strength)
80/20mg
Pregnancy
No known risks
Brands
Kaletra, Aluvia
Protein binding
98-99%
PubChem CID
11979606
MedlinePlus
a602015
ChEBI
45409
ATC code
J05AR10
DrugBank
DB00503
KEGG
D02498
Routes of administration
By mouth
Directions
Take Kaletra exactly as prescribed by your doctor.
The usual dosage is 800/200 mg by mouth once or twice daily.
Ingredients
Ingredients
The active ingredients are lopinavir and ritonavir.
Interactions
Kaletra is formulated with an ingredient, ritonavir, which is designed to boost the amount of the other medication in the drug, lopinavir. Consequently, Kaletra has many drug interactions, including:
Alfuzosin
Alprazolam
Amiodarone
Anti Hepacivirus combination products
Apalutamide
Aprepitant
Atovaquone
Avanafil
Bortezomib
Bosutinib
Budesonide
Clarithromycin
Clobetasone
Cobicistat
Darunavir
Disulfiram
Domperidone
Doxorubicin
Dronedarone
Eletriptan
Eplerenone
Ergot derivatives
Everolimus
Flecainide
Fluticasone
Fosamprenavir
Fosaprepitant
Ibrutinib
Ivabradine
Lovastatin
Lurasidone
Metronidazole
Midazolam
Pimozide
Propafenone
Quinidine
Quinine
Red yeast rice
Rifampin
Rivaroxaban
Salmeterol
Simvastatin
St. John's Wort
Tamsulosin
Triazolam
Vincristine
Voriconazole
Cautions
Kaletra has been known to cause pancreatitis in some individuals.
Your doctor should monitor your liver function before starting Kaletra.
Tell your doctor if you have a history of heart disease or arrhythmias.
Kaletra may increase blood sugar and contribute to the development of diabetes mellitus.
Side Effects
The most common side effects of Kaletra may include:
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 2171
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