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Medically Reviewed
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What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Katerzia (Amlodipine)
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Product Details
Description
Katerzia (Amlodipine) is used to treat:
- High blood pressure in adults and children who are at least 6 years old
- Coronary artery disease
- Chronic Stable Angina
- Vasospastic Angina
- Angiographically Documented Coronary Artery Disease in patients who do not have heart failure or an ejection fraction less than 40%
Fact Table
Formula
C20H25ClN2O5
License
U.S. Food and Drug Administration (FDA), US DailyMed EU EMA
Bioavailability
64–90%
Legal status
Rx-Only
Chemical Name
Amlodipine
Elimination half-life
30–50 hours
Dosage (Strength)
1mg / ml 150 ml
Pregnancy
Amlodipine can be used in pregnancy
Brands
Katerzia
Protein binding
93%
PubChem CID
2162
MedlinePlus
a692044
ChEBI
2668
ATC code
C08CA01
DrugBank
DB00381
KEGG
D07450
Routes of administration
oral suspension
Directions
Katerzia (Amlodipine) is available in a 1 mg/mL oral suspension.
You will use a measuring device to measure out your dose in milliliters. Follow the instructions that are on your prescription label.
Recommended starting dose in adults: 5 mg by mouth once daily. Do not exceed 10 mg once daily. The starting dose may be 2.5 mg in patients who are small or elderly or in patients who have liver problems.
Recommended starting dose in pediatric patients: 2.5 mg to 5 mg by mouth once daily.
Ingredients
The active ingredient contained in Katerzia is Amlodipine Benzoate, a calcium channel blocker.
Contraindications
Do not take Katerzia if you are allergic to amlodipine or any of the other ingredients in Katerzia.
Cautions
- Before you start taking Katerzia, inform your doctor:
- Of any allergies you have
- Of all the medications you take, including prescription and over-the-counter
- Of any health conditions you have
- If you are pregnant or have plans to become pregnant
- If you are breastfeeding or have plans to breastfeed
- Katerzia can cause low blood pressure.
- Katerzia can worsen chest pain and can cause an acute heart attack can occur after starting or increasing the dose of Katerzia, especially in patients who have severe obstructive coronary artery disease
- Katerzia should be stored in the refrigerator. Do not freeze.
Side Effects
Katerzia can cause drowsiness, dizziness, fatigue, and nausea.
Tell your doctor right away if you develop troublesome or persistent side effects.
Reference:
Katerzia Prescribing Information. Wilmington, MA: Azurity Pharmaceuticals; 2020.
Popular Questions
Amlodipine can be taken either in the morning or at night, depending on what works best for the individual and their daily routine. It is important to take it at the same time each day to maintain consistent blood levels. Always follow your healthcare provider's recommendations regarding the timing of your medication.
Amlodipine, a medication used to treat high blood pressure and angina, can cause side effects such as swelling of the legs or ankles (edema), dizziness, and flushing. Other potential side effects include fatigue, palpitations, and in rare cases, more serious effects like an irregular heartbeat or severe allergic reactions.
When taking amlodipine, it's important to avoid or limit grapefruit and grapefruit juice consumption, as it can increase the drug's concentration in your body and worsen side effects. Also, discuss alcohol consumption with your doctor, as it may further lower blood pressure and interact with the medication. Additionally, certain herbal supplements like ginseng and echinacea can interfere with amlodipine's effectiveness, so it's best to consult your doctor before taking any supplements while on this medication.
Amlodipine and amlodipine besylate are essentially the same medication, with the difference being in their chemical form. Amlodipine is the active ingredient responsible for the drug's therapeutic effects, while amlodipine besylate is the salt form of amlodipine. Amlodipine besylate is more stable and soluble than amlodipine, which makes it easier to formulate into tablets and other oral medications. The besylate salt does not affect the way amlodipine works in the body, so both forms are equally effective in treating conditions like high blood pressure and angina.
Amlodipine can be taken at any time of the day, but it's important to take it around the same time each day to maintain consistent levels in your body. While research suggests taking blood pressure medication at night may offer better blood pressure control, it's ultimately best to consult with your doctor to determine the optimal time for your specific needs and circumstances.
View allAmlodipine is not inherently a "bad" blood pressure medication, as it is effective for many individuals. However, like any medication, it may not be suitable for everyone and can cause side effects. Some common side effects include swelling in the ankles or feet, dizziness, flushing, and headaches. In rare cases, it can worsen angina or cause a heart attack in those with severe heart disease. Additionally, it may not be the most effective option for certain populations, such as those with liver problems. It's essential to discuss any concerns with your doctor, who can determine if amlodipine is right for you and monitor for any potential complications.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13611
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