Kesimpta (Ofatumumab)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Prescription Required

  • Product Details


    Kesimpta (ofatumumab) is a prescription medication for treating relapsing forms of multiple sclerosis (MS). It is a monoclonal antibody that targets and binds to a specific protein found on the surface of B-cells, a type of immune cell involved in the development of MS.

    Kesimpta is available in a prefilled syringe and is administered as a subcutaneous injection.

    Fact Table







    Legal status


    Chemical Name


    Elimination half-life

    14 days

    Dosage (Strength)



    Consult Doctor



    Protein binding

    Limited information

    PubChem CID

    Not Available




    Not Available

    ATC code






    Routes of administration



    The first dose is administered alongside a healthcare professional. Your healthcare provider will provide you with a schedule for subsequent injections.


    The active ingredient in Kesimpta is ofatumumab.


    Common drug-drug interactions may include:

    • Abrocitinib
    • Baricitinib
    • BCG Products
    • Cladribine
    • Coccidioides immitis Skin Test
    • COVID-19 Vaccines
    • Dengue Tetravalent Vaccine
    • Denosumab
    • Deucravacitinib
    • Filgotinib
    • Influenza Virus Vaccines
    • Leflunomide
    • Mumps- Rubella- or Varicella-Containing Live Vaccines
    • Nadofaragene Firadenovec
    • Natalizumab
    • Ocrelizumab
    • Pimecrolimus
    • Poliovirus Vaccine
    • Polymethylmethacrylate
    • Rabies Vaccine
    • Ruxolitinib
    • Sipuleucel-T
    • Tacrolimus
    • Talimogene Laherparepvec
    • Tertomotide
    • Tofacitinib
    • Typhoid Vaccine
    • Upadacitinib
    • Vaccines (Inactivated/Non-Replicating)
    • Vaccines (Live)
    • Yellow Fever Vaccine


    Do not take Kesimpta if you are allergic to ofatumumab or any other ingredient in the medication.

    Before starting Kesimpta, inform your healthcare provider if you have a history of hepatitis B infection, as the medication may reactivate the virus.

    It is important to monitor for signs of infection while using Kesimpta, as it may increase the risk of infection.

    Side Effects

    The most common side effects of Kesimpta may include:

    • Anemia
    • Back pain
    • Bronchitis
    • Chills
    • Cough
    • Decreased serum immunoglobulins
    • Diarrhea
    • Dyspnea
    • Fatigue
    • Fever
    • Headache
    • Hepatitis B
    • Herpes zoster infection
    • Hyperhidrosis
    • Hypertension
    • Hypogammaglobulinemia
    • Hypotension
    • Infection
    • Influenza
    • Infusion-related reaction
    • Injection site reaction
    • Insomnia
    • Muscle spasm
    • Nasopharyngitis
    • Neutropenia
    • Peripheral edema
    • Pneumonia
    • Porphyria cutanea tarda
    • Progressive multifocal leukoencephalopathy
    • Sepsis
    • Serious Infection
    • Sinusitis
    • Skin rash
    • Stevens-Johnson syndrome
    • Tachycardia
    • Tumor lysis syndrome
    • Upper respiratory tract infection
    • Urinary tract infection
    • Urticaria


    Kesimpta [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2020.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13855

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