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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Kisqali

Sezzle
Brand

Kisqali (Ribociclib)

Prescription Required

Strength

200mg

400mg

600mg

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  • Product Details

    Description

    Kisqali (ribociclib) is a medication used in combination with other drugs to treat breast cancer. It decreases the size of tumors by disrupting the replication cycle of the cancerous cells. You can buy Kisqali as a 200mg, 400mg, or 600mg tablet. Keep your Kisqali tablets stored at room temperature and out of reach of children.    

    Directions

    • You can take Kisqali with or without food.
    • Do not break or chew Kisqali. Swallow the tablets whole.
    • Take your Kisqali at the same time every day, preferably in the morning.   
    • Take your Kisqali precisely as your physician has prescribed.
    • If you miss a dose of Kisqali, continue with your next scheduled dose. Do not take any extra tablets to make up for a missed dose.
    • If you vomit after you take a Kisqali tablet, skip the dose and continue with your regular schedule. Do not take extra tablets to make up for doses that were vomited up.
    • The typical dose of Kisqali is 600mg once daily for 21 days, followed by seven days without treatment.

    Ingredients

    The active ingredient in Kisqali is ribociclib. For a full list of inactive ingredients, see the package insert.

    Fact Table
    Formula C23H30N8O
    License US: FDA
    Routes of administration By mouth
    Legal status Rx Only
    Chemical Name Ribociclib
    Elimination half-life 32 hours
    Dosage (Strength) 200mg, 400mg, 600mg
    Pregnancy Not assigned
    Brands Kisqali
    Protein binding 70%
    PubChem CID 44631912
    MedlinePlus a617008
    ChEBI -
    ATC code L01XE42
    DrugBank DB11730
    KEGG D10883
    Bioavailability -

    Cautions

    • Kisqali can affect your blood cells, liver, and heart. Talk to your doctor about your risks.
    • Do not take Kisqali tablets that are cracked or broken.
    • Do not take Kisqali if you have a known allergy to ribociclib or any other ingredient listed in the package insert.
    • If you have any episodes of fainting or seizures while taking Kisqali, contact your doctor or seek emergency assistance immediately. These symptoms could mean you have a dangerous heart condition.
    • Kisqali can cause lung problems. If you experience difficulty breathing while using Kisqali, contact your doctor.
    • Do not take Kisqali if you are pregnant. Talk to your doctor about the risks of using Kisqali during pregnancy.
    • Avoid grapefruit and grapefruit juice while taking Kisqali.
    • Discuss any medications you take with your physician to avoid serious drug interactions with Kisqali.

    Side Effects

    Common Kisqali side effects can include:

    • Hair loss
    • Itching
    • Constipation
    • Diarrhea
    • Nausea
    • Vomiting
    • Leukopenia
    • Neutropenia
    • Infectious disease
    • Joint pain
    • Back pain
    • Headache
    • Cough
    • Fatigue

    Serious side effects of Kisqali can include:

    • Prolonged QT interval
    • Sudden cardiac death
    • Fainting
    • Anemia
    • Febrile neutropenia
    • High-grade leukopenia
    • Lymphocytopenia
    • High-grade neutropenia
    • Interstitial lung disease
    • Pneumonitis

    Other Considerations

    Compare the Kisqali cost at Canada Pharmacy to your local drug store.

    References:

    1. Kisqali. (n.d.). Retrieved March 23, 2020
    2. DailyMed - kisqali- RIBOCICLIB TABLET, film coated. (2020). Retrieved March 23, 2020 


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13252

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