What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Lexiva

Known as Telzir in the UK

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Brand

Lexiva

Prescription Required

Strength

700mg

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  • Product Details

    Description

    LEXIVA is a prescription medication used to treat HIV infection. Left untreated, HIV infection can lead to acquired immunodeficiency syndrome (AIDS). 

    HIV is a long-term infection that weakens the immune system and leaves a person susceptible to opportunistic infections.

    LEXIVA is an antiviral HIV protease inhibitor. It works by shutting down a protein critical for HIV virus replication. LEXIVA slows down replication and prevents infections from worsening.

    Directions

    LEXIVA must be taken every day exactly as prescribed by the doctor.

    It can be taken with or without food.

    Your doctor will determine the best LEXIVA dosage. Some example regimens include:

    • Hepatic impairment: Adjusted based on directions from the prescriber
    • Treatment-naive: LEXIVA 1400 mg by mouth twice daily plus ritonavir
    • Pediatric (2 to 18 years old): Calculate based on body weight

    Protease Inhibitor-experienced adults: LEXIVA 700 mg twice daily plus ritonavir 100 mg twice daily

    Ingredients

    The active ingredient in LEXIVA is fosamprenavir.

    Interactions

    LEXIVA is contraindicated when the following medications:

    • Cisapride
    • Delavirdine
    • Dihydroergotamine
    • Ergonovine
    • Ergotamine
    • Flecainide
    • Lovastatin
    • Methylergonovine
    • Midazolam
    • Pimozide
    • Propafenone
    • Rifampin
    • Simvastatin
    • St. John's Wort
    • Triazolam

    Use caution if you are taking any of the following medications. Tell your doctor and pharmacist your full list of drugs before you start taking LEXIVA. Common drug interactions include:

    • Alprazolam
    • Amiodarone
    • Atazanavir
    • Atorvastatin
    • Bepridil
    • Calcium Channel Blockers
    • Carbamazepine
    • Clorazepate
    • Cyclosporine
    • Dexamethasone
    • Diazepam
    • Efavirenz
    • Flurazepam
    • Fluticasone
    • H2 receptor antagonists
    • Indinavir
    • Itraconazole
    • Ketoconazole
    • Lidocaine
    • Lopinavir/ritonavir
    • Methadone
    • Nelfinavir
    • Nevirapine
    • Oral contraceptives
    • Paroxetine
    • PDE5 Inhibitors
    • Phenobarbital
    • Phenytoin
    • Proton pump inhibitors
    • Quinidine
    • Rapamycin
    • Rifabutin
    • Rosuvastatin
    • Saquinavir
    • Tacrolimus
    • Trazodone
    • Tricyclic antidepressants
    • Warfarin

    Cautions

    Tell your doctor if you have a history of nephrolithiasis, diabetes, anemia, hemophilia, high cholesterol, hepatitis B or C, or a sulfonamide allergy.

    LEXIVA may cause fat redistribution and immune reconstitution syndrome.

    If a skin reaction happens while taking LEXIVA, stop taking the drug, and call your doctor’s office.

    Side Effects

    Adverse reactions from LEXIVA may include:

    • Diarrhea
    • Headache
    • Nausea
    • Rash
    • Vomiting

    For a full list of side effects, speak with your pharmacist.

    Buy LEXIVA with a valid prescription from your physician. LEXIVA can be found at Canada Pharmacy for a great LEXIVA cost.

    References

    Lexiva [package insert]. Research Triangle Park, NJ: GlaxoSmithKline; 2009.

    Product Code : 12590

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