What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Lidoderm Patch (Lidocaine)
Also Known as Versatis medicated plasters
Prescription Required
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Product Details
Description
Your doctor may prescribe Lidoderm for the treatment of minor pain, particularly nerve pain. It is indicated for the treatment of pain associated with post-herpetic neuralgia. Post-herpetic neuralgia is long-lasting pain associated with shingles.
Lidoderm patches are a topical medication placed directly on the skin.
Lidoderm patches work by blocking the initiation and conduction of nerve impulses. It decreases the membrane permeability of neurons to sodium ions, which blocks nerve signals.
Fact Table
Formula
C14H22N2O
License
US FDA, EU EMA
Bioavailability
35%
Legal status
US: OTC / Rx-only
Chemical Name
Lidocaine
Elimination half-life
1.5 h to 2 h
Dosage (Strength)
5%
Pregnancy
No Known Risk
Brands
Lidoderm Patch, Xylocaine, Ztlido
Protein binding
More than 65%
PubChem CID
3676
MedlinePlus
a682701
ChEBI
6456
ATC code
C01BB01
DrugBank
DB00281
KEGG
D00358
Routes of administration
Intravenous, subcutaneous, topical, by mouth
Directions
Apply Lidoderm patches to the affected area of the skin for 12 hours. Remove the patch for 12 hours before reapplying to the same site.
After removing a used patch, fold the patch onto itself and discard it in a place that is not accessible to children or animals.
Ingredients
The active ingredient in Lidoderm patches is lidocaine.
Interactions
Common drug-drug interactions with this medication can include:
- Antiarrhythmic Agents
- Cimetidine
- Dapsone
- Local Anesthetics
- Methemoglobinemia Associated Agents
- Nitric Oxide
- Prilocaine
- Sodium Nitrite
Cautions
Only apply Lidoderm patches to intact areas of the skin.
Do not wear Lidoderm patches for longer than prescribed. Doing so may result in high levels of lidocaine absorbing into the bloodstream and increasing the risk of side effects.
Lidoderm patches may cause irritation at the site of application.
Side Effects
Common adverse reactions to this medication may include:
- Anaphylactoid Shock
- Angioedema
- Application Site Burning
- Application Site Erythema
- Application Site Vesicles
- Apprehension
- Asthenia
- Blurred Vision
- Bradycardia
- Bronchospasm
- Bruise
- Central Nervous System Depression
- Circulatory Shock
- Confusion
- Dermatitis
- Diplopia
- Disorientation
- Dizziness
- Drowsiness
- Dysgeusia
- Dyspnea
- Euphoria
- Excitement
- Exfoliation Of Skin
- Flushing
- Headache
- Hyperesthesia
- Hypersensitivity Reaction
- Hypoesthesia
- Hypotension
- Laryngospasm
- Local Discoloration
- Local Irritation
- Localized Warm Feeling
- Loss Of Consciousness
- Metallic Taste
- Methemoglobinemia
- Nervousness
- Numbness
- Pain
- Papule
- Paresthesia
- Respiratory Depression
- Seizure
- Sensation Disorder
- Sensation Of Cold
- Shock
- Skin Blister
- Skin Depigmentation
- Skin Edema
- Skin Erosion
- Tinnitus
- Tremor
- Twitching
- Urticaria
References
Lidoderm patch [package insert]. Malvern, PA: Endo Pharmaceuticals Inc.; 2015.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 11554
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