Description
Your doctor may prescribe Lidoderm for the treatment of minor pain, particularly nerve pain. It is indicated for the treatment of pain associated with post-herpetic neuralgia. Post-herpetic neuralgia is long-lasting pain associated with shingles.
Lidoderm patches are a topical medication placed directly on the skin.
Lidoderm patches work by blocking the initiation and conduction of nerve impulses. It decreases the membrane permeability of neurons to sodium ions, which blocks nerve signals.
Fact Table |
Formula |
C14H22N2O |
License |
US FDA, EU EMA |
Bioavailability |
35% |
Legal status |
US: OTC / Rx-only |
Chemical Name |
Lidocaine |
Elimination half-life |
1.5 h to 2 h |
Dosage (Strength) |
5% |
Pregnancy |
No Known Risk |
Brands |
Lidoderm Patch, Xylocaine, Ztlido |
Protein binding |
More than 65% |
PubChem CID |
3676 |
MedlinePlus |
a682701 |
ChEBI |
6456 |
ATC code |
C01BB01 |
DrugBank |
DB00281 |
KEGG |
D00358 |
Routes of administration |
Intravenous, subcutaneous, topical, by mouth |
Directions
Apply Lidoderm patches to the affected area of the skin for 12 hours. Remove the patch for 12 hours before reapplying to the same site.
After removing a used patch, fold the patch onto itself and discard it in a place that is not accessible to children or animals.
Ingredients
The active ingredient in Lidoderm patches is lidocaine.
Interactions
Common drug-drug interactions with this medication can include:
- Antiarrhythmic Agents
- Cimetidine
- Dapsone
- Local Anesthetics
- Methemoglobinemia Associated Agents
- Nitric Oxide
- Prilocaine
- Sodium Nitrite
Cautions
Only apply Lidoderm patches to intact areas of the skin.
Do not wear Lidoderm patches for longer than prescribed. Doing so may result in high levels of lidocaine absorbing into the bloodstream and increasing the risk of side effects.
Lidoderm patches may cause irritation at the site of application.
Side Effects
Common adverse reactions to this medication may include:
- Anaphylactoid Shock
- Angioedema
- Application Site Burning
- Application Site Erythema
- Application Site Vesicles
- Apprehension
- Asthenia
- Blurred Vision
- Bradycardia
- Bronchospasm
- Bruise
- Central Nervous System Depression
- Circulatory Shock
- Confusion
- Dermatitis
- Diplopia
- Disorientation
- Dizziness
- Drowsiness
- Dysgeusia
- Dyspnea
- Euphoria
- Excitement
- Exfoliation Of Skin
- Flushing
- Headache
- Hyperesthesia
- Hypersensitivity Reaction
- Hypoesthesia
- Hypotension
- Laryngospasm
- Local Discoloration
- Local Irritation
- Localized Warm Feeling
- Loss Of Consciousness
- Metallic Taste
- Methemoglobinemia
- Nervousness
- Numbness
- Pain
- Papule
- Paresthesia
- Respiratory Depression
- Seizure
- Sensation Disorder
- Sensation Of Cold
- Shock
- Skin Blister
- Skin Depigmentation
- Skin Edema
- Skin Erosion
- Tinnitus
- Tremor
- Twitching
- Urticaria
References
Lidoderm patch [package insert]. Malvern, PA: Endo Pharmaceuticals Inc.; 2015.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 11554