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Linzess

(Known as Constella in the UK)

Prescription Required

Product Details

Description:

Linzess is a guanylate cyclase C agonist indicated in adults for the treatment of Irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC).

Ingredients:

Linaclotide

Directions:

IBS-C - Take 290mcg orally once daily. CIC - Take 145mcg orally once daily. Take on a empty stomach, at least 30 minutes prior to the first meal of the day.

Cautions:

For elderly patients, although no dose adjustment is required the treatment should be carefully monitored and periodically re-assessed Linzess is contraindicated for patients with known or suspected mechanical gastrointestinal obstruction. Should prolonged (e.g. more than 1 week) or severe diarrhoea occur, medical advice should be sought and temporary discontinuation of linaclotide until diarrhoea episode is resolved may be considered.

Side Effects:

Diarrhoea, mainly mild to moderate in intensity, occurring in less than 20% of patients. This may – as a consequence – lead to the occurrence of dehydration, hypokalaemia, blood bicarbonate decrease, dizziness, and orthostatic hypotension. Other common adverse reactions (>1%) were abdominal pain, abdominal distension and flatulence, rash.

Product Code: 13163
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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