Description
Lorzone (chlorzoxazone) is a medication that is used with rest, physical therapy, and other regimens to treat the sudden onset of musculoskeletal pain. Lorzone is not a narcotic.
Fact Table |
Formula |
C7H4ClNO2 |
License |
US DailyMed |
Bioavailability |
Well absorbed |
Legal status |
Rx-Only |
Chemical Name |
Chlorzoxazone |
Elimination half-life |
1.1 hr Duration of action 3-4 hrs |
Dosage (Strength) |
375mg, 500mg, 750mg |
Pregnancy |
Consult Doctor |
Brands |
Lorzone |
Protein binding |
98% |
PubChem CID |
2733 |
MedlinePlus |
a682577 |
ChEBI |
3655 |
ATC code |
M03BB03 |
DrugBank |
DB00356 |
KEGG |
D00771 |
Routes of administration |
By mouth |
Directions
Lorzone is available in 250 mg, 375 mg, 500 mg, and 750 mg tablets.
The typical starting dose is 250 mg to 500 mg by mouth three to four times a day.
Ingredients
The active ingredient in Lorzone is chlorzoxazone.
Contraindications
Discuss your allergies with your doctor. Do not take Lorzone if you are allergic to chlorzoxazone or any other ingredient in Lorzone.
Cautions
- Lorzone may interact with certain medications. Tell your doctor about all the medications you take. These include prescription and over-the-counter medications as well as vitamins and herbal supplements.
- Tell your doctor about your health conditions.
- Lorzone can cause liver problems. Drinking alcohol or taking other medications that can cause central nervous system depression while being treated with Lorzone can further increase the risk.
- Tell your doctor if you are pregnant or plan to become pregnant.
- Tell your doctor if you are currently breastfeeding or plan to breastfeed.
Side Effects
Lorzone is generally tolerated well but can cause side effects such as drowsiness, dizziness, lightheadedness, overstimulation, gastrointestinal bleeding, or a feeling of general discomfort. Tell your doctor if you experience side effects that bother you or will not go away.
References:
- Lorzone Prescribing Information. Bridgewater, NJ: Vertical Pharmaceuticals, LLC; 2017.
- Chlorzoxazone (Lorzone). GoodRx. Last reviewed December 20, 2021. Accessed February 4, 2022.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13597