Description
Lupron Depot-Ped is a prescription medication used to treat early-onset puberty in both male and female children. Leuprolide Acetate, a GnRH agonist drug, suppresses natural sex hormones that cause early-onset puberty, allowing patients to experience a more natural and age-appropriate progression into puberty. This medication also helps children avoid the potential stunted growth and emotional, psychological, and behavioral problems associated with central precocious puberty. Buy Lupron Depot-Ped from Canada Pharmacy to ensure the best price.
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Fact Table
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Formula
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C59H84N16O12
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License
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US FDA, US DailyMed, EU EMA
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Bioavailability
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4% to 18%
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Legal status
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Rx-Only
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Chemical Name
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Leuprorelin
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Elimination half-life
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3 hours
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Dosage (Strength)
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30mg Prefilled Dual Chamber Syringe
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Pregnancy
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Consult a healthcare provider for advice
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Brands
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Lupron Depot Ped
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Protein binding
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43% and 49%
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PubChem CID
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657181
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MedlinePlus
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a685040
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ChEBI
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Not Assigned
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ATC code
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L02AE02
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DrugBank
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DB00007
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KEGG
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D08113
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Routes of administration
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implant, subcutaneous, intramuscular
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Directions
Lupron Depot-Ped injections should only be administered by a physician in a medical office environment.
Lupron pediatric is administered according to two dosing schedules:
Lupron Depot-Ped 3-month dosing involves the child receiving 4 injections per year.
Lupron Depot-Ped 1-month dosing involves the child receiving 12 injections per year, always administered by a physician.
Ingredients
The active ingredient in Lupron Depot-Ped is Leuprolide Acetate.
Cautions
Use Lupron Depot-Ped with caution in children who have a history of seizures, and only if specifically approved by a doctor in these instances. Children with existing mental health concerns may not be suitable for Lupron Depot-Ped. This decision should be made solely by your doctor.
Interactions
Negative drug interactions are possible between Lupron Depot-Ped and other prescription medications, including but not limited to albuterol, zolpidem, amlodipine, atorvastatin, diphenhydramine, cetirizine, loratadine, clonazepam, diazepam, fluticasone, hydrocortisone, lisinopril, mometasone, mupirocin, beclomethasone, simethicone, montelukast, levothyroxine, trazodone, and cetirizine. Inform your doctor of all medications you are currently taking before receiving a prescription for Lupron Depot-Ped.
Side Effects
Side effects from the use of Lupron pediatric medication are possible. Some children may experience pain, swelling, or abscesses at the injection site, weight gain, body pain, headache, acne, red and itchy rash with white scales (seborrhea), mood changes, or changes to genitalia. If side effects are observed, discontinue the child's use of the medication and consult your doctor regarding alternative medications for early-onset puberty prevention.
Frequently Asked Questions about Lupron Depot-Ped (Leuprolide Acetate)
What is Lupron Depot-Ped (Leuprolide Acetate) used for?
Lupron Depot-Ped is prescribed for the treatment of children with central precocious puberty (CPP).
How is Lupron Depot-Ped administered?
Lupron Depot-Ped is given as a single-dose injection into the child's muscle every 1 month, 3 months, or 6 months by a doctor or trained nurse.
What are the common side effects of Lupron Depot-Ped?
Common side effects include injection site reactions, emotional lability, weight gain, headache, mood changes, acne/seborrhea, vaginitis/vaginal bleeding, and gastrointestinal symptoms.
Can Lupron Depot-Ped cause an initial increase in hormones?
Yes, during the first few weeks of treatment, Lupron Depot-Ped can cause an increase in hormones, leading to a temporary increase in signs of puberty, including vaginal bleeding.
Are there any psychiatric side effects associated with Lupron Depot-Ped?
Yes, psychiatric events such as emotional lability, irritability, and aggression have been reported in patients taking Lupron Depot-Ped.
Is there a risk of seizures with Lupron Depot-Ped?
Yes, there have been postmarketing reports of seizures in patients receiving GnRH agonists like Lupron Depot-Ped, especially in those with a history of seizures, epilepsy, or taking seizure-related medications.
What is Pseudotumor Cerebri and is it associated with Lupron Depot-Ped?
Pseudotumor Cerebri, a condition with symptoms like headache and vision problems, has been reported in patients receiving GnRH agonists, including Lupron Depot-Ped.
Is Lupron Depot-Ped safe for children under 1 year old?
The safety and effectiveness of Lupron Depot-Ped have not been established in pediatric patients less than 1 year old.
What should be done before starting Lupron Depot-Ped treatment?
Before starting treatment, the child's doctor should conduct tests to confirm the diagnosis of CPP. Regular exams and blood tests are also recommended during treatment.
What are contraindications for using Lupron Depot-Ped?
Lupron Depot-Ped should not be used in patients with hypersensitivity to GnRH, GnRH agonists, or any of its excipients, and in pregnancy due to the risk of fetal harm.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 14847
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