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Luvox CR (Fluvoxamine)
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Product Details
Description
Luvox CR is a selective serotonin reuptake inhibitor (SSRI) approved for treating obsessive-compulsive disorder (OCD) in children through adults. It helps to regulate the moods and thoughts associated with OCD.
Fact Table
Formula
C15H21F3N2O2
License
US FDA, EU EMA
Bioavailability
53%
Legal status
Rx-only
Chemical Name
Fluvoxamine
Elimination half-life
12–13 hours
Dosage (Strength)
100mg, 150mg
Pregnancy
Consult Doctor
Brands
Luvox, Faverin
Protein binding
77–80%
PubChem CID
5324346
MedlinePlus
a695004
ChEBI
5138
ATC code
N06AB08
DrugBank
DB00176
KEGG
D07984
Routes of administration
By mouth
Directions
The starting dosage is 100 mg by mouth once daily. The dosage can be increased to a maximum of 300 mg by mouth once daily.
Ingredients
The active ingredient is fluvoxamine.
Interactions
Common interactions include:
- Abrocitinib
- Agomelatine
- Alcohol
- Alosetron
- Astemizole
- Bemiparin
- Bendamustine
- Bromopride
- Cilostazol
- Cisapride
- Citalopram
- CloZAPine
- Dapoxetine
- DULoxetine
- Enoxaparin
- Erlotinib
- Fenfluramine
- Gilteritinib
- Heparin
- Lemborexant
- Linezolid
- Lomitapide
- Lonafarnib
- Mavacamten
- Melatonin
- Methylene Blue
- Methysergide
- Monoamine Oxidase Inhibitors
- Nonsteroidal Anti-Inflammatory Agents
- Pimozide
- Pirfenidone
- Pomalidomide
- Propranolol
- Ramelteon
- Rasagiline
- Safinamide
- Selegiline
- Sirolimus
- Tasimelteon
- Terfenadine
- Theophylline Derivatives
- Thioridazine
- TiZANidine
- Ubrogepant
- Urokinase
Cautions
For a full list of precautions for SSRIs, speak with your doctor or pharmacist.
Side Effects
Common adverse reactions include:
- Abdominal pain
- Abnormal dreams
- Abnormal gait
- Abnormal hepatic function tests
- Abnormality in thinking
- Acne vulgaris
- Activation syndrome
- Acute renal failure
- Aggressive behavior
- Agitation
- Agranulocytosis
- Akinesia
- Amblyopia
- Amenorrhea
- Amnesia
- Anaphylaxis
- Anemia
- Angina pectoris
- Angioedema
- Angle-closure glaucoma
- Anorexia
- Anorgasmia
- Anuria
- Anxiety
- Apathy
- Aplastic anemia
- Apnea
- Asthma
- Ataxia
- Blurred vision
- Bradycardia
- Bronchitis
- Bruxism
- Bullous skin disease
- Cardiac conduction delay
- Cardiomyopathy
- Cardiorespiratory arrest
- Central nervous system stimulation
- Cerebrovascular accident
- Chest pain
- Chills
- Cholecystitis
- Cholelithiasis
- Colitis
- Constipation
- Crying
- Decreased libido
- Decreased white blood cell count
- Delirium
- Dental caries
- Depression
- Diaphoresis
- Diarrhea
- Diplopia
- Dizziness
- Drowsiness
- Drowsiness (neonatal)
- Dysarthria
- Dysgeusia
- Dyskinesia
- Dyspepsia
- Dysphagia
- Dyspnea
- Dystonia
- Ecchymoses
- Edema
- Ejaculatory disorder
- Epistaxis
- Extrapyramidal reaction
- Fatigue
- Fever
- First-degree atrioventricular block
- Flatulence
- Flu-like symptoms
- Gastroesophageal reflux disease
- Gastrointestinal hemorrhage
- Gingivitis
- Glossalgia
- Goiter
- Hallucination
- Headache
- Hematemesis
- Hematuria
- Hemoptysis
- Hepatitis
- Homicidal ideation
- Hypercholesterolemia
- Hyperglycemia
- Hyperkinesia
- Hypermenorrhea
- Hypersensitivity reaction
- Hypertension
- Hypertonia
- Hypoglycemia
- Hypokalemia
- Hypokinesia
- Hyponatremia
- Hypotension
- Hypothyroidism
- Iga vasculitis
- Impotence
- Impulsivity
- Increased cough
- Insomnia
- Interstitial pulmonary disease
- Intestinal obstruction
- Intoxicated feeling
- Irritability
- Jaundice
- Jitteriness
- Laryngismus
- Laryngitis
- Lethargy
- Leukocytosis
- Leukopenia
- Loss of consciousness
- Lymphadenopathy
- Malaise
- Manic reaction
- Melena
- Myalgia
- Myasthenia
- Myocardial infarction
- Myoclonus
- Myopathy
- Nausea
- Nervousness
- Neuroleptic malignant syndrome (stevens 2008)
- Outbursts of anger
- Pain
- Palpitations
- Pancreatitis
- Paralysis
- Paresthesia
- Parkinsonian-like syndrome
- Pericarditis
- Pharyngitis
- Polyuria
- Porphyria
- Priapism
- Prolonged qt interval on ECG
- Psychoneurosis
- Psychotic reaction
- Purpura
- Raynaud's phenomenon
- Renal insufficiency
- Rhabdomyolysis
- Seizure
- Serotonin syndrome
- Sexual disorder
- Shock
- SIADH
- Sinusitis
- St segment changes on ecg
- Stevens-johnson syndrome
- Suicidal tendencies
- Supraventricular extrasystole
- Syncope
- Tachycardia
- Tardive dyskinesia
- Thrombocytopenia
- Thromboembolism
- Tooth abscess
- Tooth loss
- Toothache
- Toxic epidermal necrolysis
- Tremor
- Twitching
- Upper respiratory tract infection
- Urinary frequency
- Urinary retention
- Urinary tract infection
- Vasculitis
- Vasodilation
- Ventricular arrhythmia
- Ventricular tachycardia
- Viral infection
- Vomiting
- Weakness
- Weight gain
- Weight loss
- Xerostomia
- Yawning
References
Luvox CR [package insert]. Palo Alto, CA: Jazz Pharmaceuticals; 2011.
Frequently Asked Questions about Luvox CR (Fluvoxamine)
What is Luvox CR used for?
Luvox CR is utilized to treat obsessive-compulsive disorders (OCD) by increasing the amount of serotonin, a substance that helps regulate mood, in the brain.
What are the common side effects of Luvox CR?
Common side effects include nausea, vomiting, drowsiness, dizziness, loss of appetite, trouble sleeping, weakness, and sweating.
Are there any serious side effects associated with Luvox CR?
Yes, serious side effects may include skin rash, blisters, fever, joint pain, mood or behavior changes, anxiety, panic attacks, trouble sleeping, impulsiveness, irritableness, agitation, hostility, aggression, restlessness, hyperactivity, increased depression, thoughts of self-harm, and racing thoughts.
Are there any warnings associated with Luvox CR?
Luvox CR has been associated with an increased risk of suicidal thoughts or actions in children and young adults. It is not approved for use in all children, and those taking it should be monitored closely for signs like low mood, nervousness, restlessness, panic attacks, or changes in mood or actions.
How should I take Luvox CR?
It's important to follow the doctor's instructions when taking Luvox CR. Do not stop taking it abruptly as it may increase the risk of side effects. If needed to stop, it should be done gradually as directed by the doctor.
Can I drive or operate heavy machinery while taking Luvox CR?
Avoid driving and doing other tasks that require alertness until you know how Luvox CR affects you.
Can I drink alcohol while taking Luvox CR?
It's advisable to avoid drinking alcohol while taking Luvox CR.
Can Luvox CR cause bleeding?
Luvox CR may raise the chance of bleeding, which in some cases can be life-threatening. It's important to talk with your doctor if you have concerns about this risk.
How long does it take for Luvox CR to work?
It may take several weeks to see the full effects of Luvox CR.
Is Luvox CR safe for older adults?
If you are 65 or older, use Luvox CR with care as you could experience more side effects.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 10860
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