What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Megace (Megestrol)
Prescription Required
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Related Products & Conditions
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Product Details
Description
MEGACE (megestrol) is a prescription hormone product that can be prescribed for multiple conditions. It can be used to stimulate appetite and to treat certain types of cancer.
- Anorexia or cachexia associated with AIDS
- Cancer-related cachexia
- Breast cancer
- Endometrial cancer
MEGACE stimulates appetite by affecting the hormones that make a person feel full.
MEGACE is a synthetic progesterone that mimics the effects of natural progesterone in the body. It blocks luteinizing hormone, which can increase the growth of certain breast and endometrial cancers.
Fact Table
Formula
C24H32O4
License
US FDA
Bioavailability
100%
Legal status
Rx-only
Chemical Name
Megestrol
Elimination half-life
34 hours
Dosage (Strength)
160mg
Pregnancy
Consult Doctor
Brands
Megace
Protein binding
82%
PubChem CID
11683
MedlinePlus
a682003
ChEBI
6723
ATC code
G03AC05
DrugBank
DB00351
KEGG
D00952
Routes of administration
By mouth
Directions
The MEGACE dose will vary depending on what it has been prescribed for. Take MEGACE exactly as prescribed by your doctor.
If being used to treat cancer, take it as prescribed by your oncologist.
- Anorexia or cachexia associated with AIDS: MEGACE oral suspension, 625-800 mg by mouth daily
- Cancer-related cachexia: MEGACE tablets, 160-800 mg by mouth every day in divided doses
- Breast cancer: MEGACE tablets, 40 mg by mouth four times daily for at least two months
- Endometrial cancer: MEGACE tablets, 40 to 320 mg by mouth in divided doses for at least two months
Ingredients
The active ingredient in MEGACE is megestrol.
Cautions
Tell your doctor if you have a history of adrenal suppression, thromboembolism, or diabetes.
Interactions
Common drug interactions with MEGACE can include:
- Anticoagulants
- Defetilide
- Pamolidomide
- Ulipristal
Speak with your doctor or pharmacist to learn about all the drug interactions that may impact your health.
Side Effects
Common adverse reactions with MEGACE may include:
- Abdominal pain
- Albuminuria
- Alopecia
- Candidiasis
- Cough
- Decreased libido
- Diarrhea
- Dyspepsia
- Edema
- Fever
- Flatulence
- Gynecomastia
- Headache
- Hyeprtension
- Hyperglycemia
- Impotence
- Insomnia
- Nausea
- Pain
- Palpitations
- Skin rash
- Urinary incontinence
- Urinary tract infection
- Vomiting
- Weakness
Buy MEGACE online with a valid prescription from your doctor. If you are using MEGACE for cancer treatment, tell your oncologist where you are getting your medication.
References
Megace [package insert]. Princeton, New Jersey: Bristol-Myers Squibb; 2012.
Frequently Asked Questions about Megace (Megestrol)
What is Megace (Megestrol)?
Megace is a prescription medication that contains the active ingredient Megestrol. It is a synthetic progestin hormone used to treat various medical conditions, including appetite loss, weight loss, and cachexia (muscle wasting) in patients with conditions like cancer and HIV/AIDS.
How does Megace work?
Megace works by mimicking the effects of the hormone progesterone in the body. It can increase appetite and promote weight gain in individuals who are experiencing unintentional weight loss.
Who can benefit from Megace treatment?
Megace is typically prescribed to individuals with conditions such as cancer or HIV/AIDS who are experiencing significant weight loss and muscle wasting. It is not a first-line treatment and is usually considered when other interventions have not been effective.
How is Megace administered?
Megace is available in both oral tablet and oral suspension forms. The specific dosage and treatment regimen will be determined by your healthcare provider based on your medical condition.
Are there any common side effects associated with Megace?
Yes, Megace may have side effects. Common side effects can include increased appetite, weight gain, fluid retention, and changes in mood. It's essential to discuss potential side effects with your healthcare provider.
Can Megace be taken with other medications?
It's crucial to inform your healthcare provider about all the medications, supplements, or herbal remedies you are taking, as some may interact with Megace and affect its effectiveness.
Is it safe to use Megace during pregnancy?
Megace should not be used during pregnancy unless the potential benefits outweigh the risks. If you are pregnant or planning to become pregnant, consult your healthcare provider for guidance.
Can Megace be taken while breastfeeding?
Megace may pass into breast milk and could potentially harm a nursing infant. If you are breastfeeding, discuss the risks and benefits with your healthcare provider.
How long will I need to take Megace?
The duration of Megace treatment can vary depending on your medical condition and how well you respond to the medication. Your healthcare provider will provide guidance on the length of treatment.
What should I do if I miss a dose of Megace?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2404
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