What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Megace (Megestrol)
Prescription Required
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Product Details
Description
MEGACE (megestrol) is a prescription hormone product that can be prescribed for multiple conditions. It can be used to stimulate appetite and to treat certain types of cancer.
- Anorexia or cachexia associated with AIDS
- Cancer-related cachexia
- Breast cancer
- Endometrial cancer
MEGACE stimulates appetite by affecting the hormones that make a person feel full.
MEGACE is a synthetic progesterone that mimics the effects of natural progesterone in the body. It blocks luteinizing hormone, which can increase the growth of certain breast and endometrial cancers.
Fact Table
Formula
C24H32O4
License
US FDA
Bioavailability
100%
Legal status
Rx-only
Chemical Name
Megestrol
Elimination half-life
34 hours
Dosage (Strength)
160mg
Pregnancy
Consult Doctor
Brands
Megace
Protein binding
82%
PubChem CID
11683
MedlinePlus
a682003
ChEBI
6723
ATC code
G03AC05
DrugBank
DB00351
KEGG
D00952
Routes of administration
By mouth
Directions
The MEGACE dose will vary depending on what it has been prescribed for. Take MEGACE exactly as prescribed by your doctor.
If being used to treat cancer, take it as prescribed by your oncologist.
- Anorexia or cachexia associated with AIDS: MEGACE oral suspension, 625-800 mg by mouth daily
- Cancer-related cachexia: MEGACE tablets, 160-800 mg by mouth every day in divided doses
- Breast cancer: MEGACE tablets, 40 mg by mouth four times daily for at least two months
- Endometrial cancer: MEGACE tablets, 40 to 320 mg by mouth in divided doses for at least two months
Ingredients
The active ingredient in MEGACE is megestrol.
Interactions
Common drug interactions with MEGACE can include:
- Anticoagulants
- Defetilide
- Pamolidomide
- Ulipristal
Speak with your doctor or pharmacist to learn about all the drug interactions that may impact your health.
Cautions
Tell your doctor if you have a history of adrenal suppression, thromboembolism, or diabetes.
Side Effects
Common adverse reactions with MEGACE may include:
- Abdominal pain
- Albuminuria
- Alopecia
- Candidiasis
- Cough
- Decreased libido
- Diarrhea
- Dyspepsia
- Edema
- Fever
- Flatulence
- Gynecomastia
- Headache
- Hyeprtension
- Hyperglycemia
- Impotence
- Insomnia
- Nausea
- Pain
- Palpitations
- Skin rash
- Urinary incontinence
- Urinary tract infection
- Vomiting
- Weakness
Find a great MEGACE cost by searching online at Canada Drugs Direct. Buy MEGACE online with a valid prescription from your doctor. If you are using MEGACE for cancer treatment, tell your oncologist where you are getting your medication.
References
Megace [package insert]. Princeton, New Jersey: Bristol-Myers Squibb; 2012.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 2404
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