Description
Your doctor may prescribe Mirapex ER to treat Parkinson's disease.
Parkinson's disease is a chronic condition that typically develops in adults aged 60 years or older. Symptoms can affect all systems in the body and may include:
- Difficulty speaking
- Difficulty walking
- Dizziness
- Fatigue
- Muscle rigidity
- Problems with coordination
- Slow bodily movement
- Stiff muscles
- Tremor
Mirapex ER is a dopamine agonist that works by binding to D2 dopamine receptors, which stimulates the activity of cells in the nervous system. Activating dopamine receptors helps to reduce the symptoms of Parkinson's disease.
Fact Table |
Formula |
C10H17N3S |
License |
US FDA, EU EMA |
Bioavailability |
More than 90% |
Legal status |
Rx-only |
Chemical Name |
Pramipexole |
Elimination half-life |
8–12 hours |
Dosage (Strength) |
0.375mg, 0.75mg, 1.5mg, 3.0mg |
Pregnancy |
No Known Risk |
Brands |
Mirapex, Mirapexin, Sifrol |
Protein binding |
15% |
PubChem CID |
119570 |
MedlinePlus |
a697029 |
ChEBI |
8356 |
ATC code |
N04BC05 |
DrugBank |
DB00413 |
KEGG |
D05575 |
Routes of administration |
By mouth |
Directions
Once you have your prescription and buy Mirapriex ER, the starting Mirapex ER dosage is 0.375 mg taken orally once daily.
The maximum recommended dose is 4.5 mg taken orally once daily.
Ingredients
The active ingredient in Mirapex ER is pramipexole.
Interactions
Common drug-drug interactions with this medication can include:
- Alizapride
- Amifostine
- Amisulpride
- Antipsychotic Agents (First Generation)
- Antipsychotic Agents (Second Generation)
- Bromperidol
- Fexinidazole
- Methotrimeprazine
- Metoclopramide
- Obinutuzumab
- Risdiplam
- Sulpiride
- Tafenoquine
Cautions
Once you are prescribed and buy Mirapex ER, use caution if you have a history of low blood pressure.
Mirapex ER can cause problems with impulse control.
Use caution if you have a history of kidney problems.
Hallucinations may occur while using this drug and are more likely in older adults.
Side Effects
Potential adverse reactions with this drug can include:
- Abnormal dreams
- Abnormal gait
- Accidental injury
- Amnesia
- Anorexia
- Asthenia
- Chest pain
- Confusion
- Constipation
- Dermatologic disorders
- Diarrhea
- Dizziness
- Drowsiness
- Dyskinesia
- Dyspnea
- Dystonia
- Edema
- Extrapyramidal reaction
- Falling
- Fatigue
- Hallucination
- Headache
- Hypertonia
- Impulse control disorder
- Influenza
- Insomnia
- Limb pain
- Muscle spasm
- Nasal congestion
- Nausea
- Orthostatic hypotension
- Peripheral edema
- Restless leg syndrome
- Sleep disorder
- Upper abdominal pain
- Urinary frequency
- Vertigo
- Vomiting
- Weight loss
- Xerostomia
References
Mirapex ER [package insert]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc. ; 2014.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 11498