What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mirapex ER (Pramipexole ER)
Also Known as Mirapexin P/R
Prescription Required
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Product Details
Description
Your doctor may prescribe Mirapex ER to treat Parkinson's disease.
Parkinson's disease is a chronic condition that typically develops in adults aged 60 years or older. Symptoms can affect all systems in the body and may include:
- Difficulty speaking
- Difficulty walking
- Dizziness
- Fatigue
- Muscle rigidity
- Problems with coordination
- Slow bodily movement
- Stiff muscles
- Tremor
Mirapex ER is a dopamine agonist that works by binding to D2 dopamine receptors, which stimulates the activity of cells in the nervous system. Activating dopamine receptors helps to reduce the symptoms of Parkinson's disease.
Fact Table
Formula
C10H17N3S
License
US FDA, EU EMA
Bioavailability
More than 90%
Legal status
Rx-only
Chemical Name
Pramipexole
Elimination half-life
8–12 hours
Dosage (Strength)
0.375mg, 0.75mg, 1.5mg, 3.0mg
Pregnancy
No Known Risk
Brands
Mirapex, Mirapexin, Sifrol
Protein binding
15%
PubChem CID
119570
MedlinePlus
a697029
ChEBI
8356
ATC code
N04BC05
DrugBank
DB00413
KEGG
D05575
Routes of administration
By mouth
Directions
Once you have your prescription and buy Mirapriex ER, the starting Mirapex ER dosage is 0.375 mg taken orally once daily.
The maximum recommended dose is 4.5 mg taken orally once daily.
Ingredients
The active ingredient in Mirapex ER is pramipexole.
Interactions
Common drug-drug interactions with this medication can include:
- Alizapride
- Amifostine
- Amisulpride
- Antipsychotic Agents (First Generation)
- Antipsychotic Agents (Second Generation)
- Bromperidol
- Fexinidazole
- Methotrimeprazine
- Metoclopramide
- Obinutuzumab
- Risdiplam
- Sulpiride
- Tafenoquine
Cautions
Once you are prescribed and buy Mirapex ER, use caution if you have a history of low blood pressure.
Mirapex ER can cause problems with impulse control.
Use caution if you have a history of kidney problems.
Hallucinations may occur while using this drug and are more likely in older adults.
Side Effects
Potential adverse reactions with this drug can include:
- Abnormal dreams
- Abnormal gait
- Accidental injury
- Amnesia
- Anorexia
- Asthenia
- Chest pain
- Confusion
- Constipation
- Dermatologic disorders
- Diarrhea
- Dizziness
- Drowsiness
- Dyskinesia
- Dyspnea
- Dystonia
- Edema
- Extrapyramidal reaction
- Falling
- Fatigue
- Hallucination
- Headache
- Hypertonia
- Impulse control disorder
- Influenza
- Insomnia
- Limb pain
- Muscle spasm
- Nasal congestion
- Nausea
- Orthostatic hypotension
- Peripheral edema
- Restless leg syndrome
- Sleep disorder
- Upper abdominal pain
- Urinary frequency
- Vertigo
- Vomiting
- Weight loss
- Xerostomia
References
Mirapex ER [package insert]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc. ; 2014.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 11498
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