What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mirena
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Product Details
Description
Mirena is a sterile, progesterone-releasing intrauterine device (IUD). It can be prescribed and inserted by your healthcare provider for the following reasons:
- Contraception
- Treatment of heavy menstrual bleeding
IUDs are inserted through the vaginal canal into the uterus. They are designed to release levonorgestrel 20 mcg per day over five years. Mirena should be replaced by a healthcare provider every five years. Fifty percent of the original amount of drug remains after five years.Fact Table
Formula
C21H28O2
License
US DailyMed
Bioavailability
85–100%
Legal status
Rx-only
Chemical Name
Levonorgestrel
Elimination half-life
24–32 hours
Dosage (Strength)
52mg
Pregnancy
Consult Doctor
Brands
Mirena
Protein binding
98%
PubChem CID
13109
MedlinePlus
a610021
ChEBI
6443
ATC code
G03AC03
DrugBank
DB00367
KEGG
D00950
Routes of administration
Device
Directions
Mirena should only be inserted by a licensed and trained healthcare professional. Before purchase, confirm that your healthcare provider agrees.
Ingredients
The active ingredient in Mirena 52 mg is levonorgestrel, which is released at a rate of 20 mcg per day.
Interactions
IUDs are less likely to cause drug-drug interactions because the drug is released directly into the uterus, and only a small amount reached the blood.
However, tell your doctor and pharmacist about all the medications you are taking before starting Mirena. Drug-drug interactions may include:
- Apalutamide
- Bexarotene
- Bosentan
- Carbamazepine
- Cenobamate
- Dabrafenib
- Dexamethasone
- Efavirenz
- Elagolix, estradiol, and norethindrone therapy pack
- Enzalutamide
- Eslicarbazepine
- Etravirine
- Fosphenytoin
- Lorlatinib
- Lumacaftor
- Lumacaftor-ivacaftor
- Mitotane
- Modafinil
- Nafcillin
- Pexidartinib
- Phenobarbital
- Phenytoin
- Primidone
- Rifabutin
- Rifampin (rifampicin)
- Rifapentine
- St. John's wort
Cautions
If you become pregnant while Mirena is inserted, it should be removed by your healthcare provider.
Use caution if you are taking anticoagulants while using Mirena.
Use caution if you have a history of migraines.
Use with caution if you have a history of cardiac problems like high blood pressure, arterial disease, or myocardial infarction.
Side Effects
Common side effects may include:
- Abdominal pain
- Amenorrhea
- Intermenstrual bleeding and spotting
- Ovarian cysts
- Pelvic pain
- Uterine bleeding
- Vaginal bleeding
Frequently Asked Questions about Mirena
What is Mirena?
Mirena is a hormonal intrauterine device (IUD) that is inserted into the uterus by a healthcare provider. It is a long-acting and reversible contraceptive method that releases a hormone called levonorgestrel to prevent pregnancy.
How does Mirena work?
Mirena works by releasing a small amount of levonorgestrel, a synthetic progestin hormone, directly into the uterus. This hormone thickens cervical mucus, making it difficult for sperm to reach the egg. It also affects the uterine lining, making it less receptive to implantation.
Is Mirena suitable for everyone?
Mirena is not suitable for everyone. It may not be recommended for individuals with certain medical conditions or those with a history of pelvic infections. A healthcare provider will assess whether Mirena is a suitable option based on an individual's medical history.
Is Mirena reversible?
Yes, Mirena is reversible. Once it is removed, fertility typically returns quickly, allowing individuals to become pregnant if they wish.
What are the potential side effects of Mirena?
Common side effects of Mirena may include irregular menstrual bleeding, changes in menstrual flow, abdominal pain, and headaches. Some individuals may experience more serious side effects, such as device expulsion or perforation of the uterus.
Does Mirena protect against sexually transmitted infections (STIs)?
No, Mirena does not protect against STIs. It is solely a contraceptive method and does not provide any protection against infections. The use of condoms or other barrier methods is recommended to reduce the risk of STIs.
Can Mirena be used as a treatment for heavy menstrual bleeding?
Yes, Mirena is sometimes used as a treatment for heavy menstrual bleeding (menorrhagia). The hormone released by Mirena can help reduce menstrual flow in some individuals.
Is Mirena painful to insert?
The insertion of Mirena can cause discomfort or cramping for some individuals. However, the procedure is typically brief and well-tolerated. Pain relief measures may be used during insertion.
How is Mirena inserted and removed?
Mirena is inserted by a healthcare provider during an office visit. The removal process is also performed by a healthcare provider. Both procedures involve the use of specialized instruments.
Can Mirena be used as emergency contraception?
Mirena is not intended for use as emergency contraception. Emergency contraception methods, such as emergency contraceptive pills, should be used if contraception is needed after unprotected intercourse.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9580
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