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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Movantik (Naloxegol)

Also Known as Moventig

Brand

Movantik (Naloxegol)

Prescription Required

Strength
Qty
12.5mg
25mg

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  • Product Details

    Description

    Movantik (naloxegol) is a prescription medication used to treat constipation caused by opioids in adult patients with long-lasting pain that isn't caused by cancer.

    Movantik is available in 12.5 mg and 25 mg oral tablets.


    Fact Table

    Formula

    C34H53NO11

    License

    EU EMA, US DailyMed

    Bioavailability

    -

    Legal status

    Rx-Only

    Chemical Name

    Naloxegol

    Elimination half-life

    6–11 h

    Dosage (Strength)

    12.5mg, 25mg

    Pregnancy

    Consult Doctor

    Brands

    Movantik

    Protein binding

    4.2%

    PubChem CID

    56959087

    MedlinePlus

    a615016

    ChEBI

    82975

    ATC code

    A06AH03

    DrugBank

    DB09049

    KEGG

    D10479

    Routes of administration

    Oral

    Directions

    Movantik should be taken as prescribed by your doctor. Notify your doctor or pharmacist about any questions or concerns you may have. 

    The recommended dose is 12.5 to 25 mg by mouth once daily on an empty stomach. It should be taken at least one hour before or two hours after the first meal of the day. Do not take Movantik with grapefruit or grapefruit juice. 

    The dose may be lower in patients with kidney problems. 

    Ingredients

    The active ingredient in Movantik is naloxegol oxalate.

    Inactive ingredients include mannitol, cellulose microcrystalline, croscarmellose sodium, magnesium stearate, and propyl gallate. The coating of the tablet contains hypromellose, titanium dioxide, polyethylene glycol, iron oxide red, and iron oxide black. 

    Contraindications

    Some patients should avoid Movantik, including those with gastrointestinal obstruction or are at risk of another obstruction.

    Cautions

    • Before you begin taking Movantik, you should inform your doctor of:
      • All the medications you take
      • Your allergies
      • Your medical history and health problems
      • Your pregnancy or breastfeeding status
    • Symptoms of opioid withdrawal, including excessive sweating, chills, diarrhea, stomach pain, anxiety, and irritability, can occur with Movantik treatment. Seek medical care if any of these effects occur.
    • Severe stomach pain with or without diarrhea can occur with Movantik treatment. Seek medical care if you develop these effects.
    • Gastrointestinal perforation can occur with Movantik treatment. Seek medical care if you develop severe, persistent, or worsening stomach pain.

    Side Effects

    Like all medications, Movantik can cause side effects. The most common include stomach pain, diarrhea, nausea, gas, vomiting, and headache. However, these may not be all the side effects that occur. 

    Notify your doctor of any bothersome or persistent side effects.

    Reference:

    1. Movantik (naloxegol) tablets, for oral use. Raleigh, NC: RedHill Biopharma Inc.; 2020.

    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13177

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