What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Movantik (Naloxegol)
Also Known as Moventig
Prescription Required
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Product Details
Description
Movantik (naloxegol) is a prescription medication used to treat constipation caused by opioids in adult patients with long-lasting pain that isn't caused by cancer.
Movantik is available in 12.5 mg and 25 mg oral tablets.
Fact Table
Formula
C34H53NO11
License
EU EMA, US DailyMed
Bioavailability
-
Legal status
Rx-Only
Chemical Name
Naloxegol
Elimination half-life
6–11 h
Dosage (Strength)
12.5mg, 25mg
Pregnancy
Consult Doctor
Brands
Movantik
Protein binding
4.2%
PubChem CID
56959087
MedlinePlus
a615016
ChEBI
82975
ATC code
A06AH03
DrugBank
DB09049
KEGG
D10479
Routes of administration
Oral
Directions
Movantik should be taken as prescribed by your doctor. Notify your doctor or pharmacist about any questions or concerns you may have.
The recommended dose is 12.5 to 25 mg by mouth once daily on an empty stomach. It should be taken at least one hour before or two hours after the first meal of the day. Do not take Movantik with grapefruit or grapefruit juice.
The dose may be lower in patients with kidney problems.
Ingredients
The active ingredient in Movantik is naloxegol oxalate.
Inactive ingredients include mannitol, cellulose microcrystalline, croscarmellose sodium, magnesium stearate, and propyl gallate. The coating of the tablet contains hypromellose, titanium dioxide, polyethylene glycol, iron oxide red, and iron oxide black.
Contraindications
Some patients should avoid Movantik, including those with gastrointestinal obstruction or are at risk of another obstruction.
Cautions
- Before you begin taking Movantik, you should inform your doctor of:
- All the medications you take
- Your allergies
- Your medical history and health problems
- Your pregnancy or breastfeeding status
- Symptoms of opioid withdrawal, including excessive sweating, chills, diarrhea, stomach pain, anxiety, and irritability, can occur with Movantik treatment. Seek medical care if any of these effects occur.
- Severe stomach pain with or without diarrhea can occur with Movantik treatment. Seek medical care if you develop these effects.
- Gastrointestinal perforation can occur with Movantik treatment. Seek medical care if you develop severe, persistent, or worsening stomach pain.
Side Effects
Like all medications, Movantik can cause side effects. The most common include stomach pain, diarrhea, nausea, gas, vomiting, and headache. However, these may not be all the side effects that occur.
Notify your doctor of any bothersome or persistent side effects.
Reference:
- Movantik (naloxegol) tablets, for oral use. Raleigh, NC: RedHill Biopharma Inc.; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13177
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