What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Myleran (Busulfan)


Myleran (Busulfan)

Prescription Required


You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

We don't have this generic product yet!

Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.

  • Product Details


    Myleran (busulfan) is an alkylating agent used for the palliative treatment of chronic myelogenous leukemia.

    Myleran (busulfan) is available in a scored 2 mg oral tablet.

    Fact Table




    US FDA, EU EMA, US DailyMed



    Legal status


    Chemical Name


    Elimination half-life

    2.5 hours

    Dosage (Strength)






    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Adult Myleran dosage for remission induction: 4 mg to 8 mg by mouth daily.


    Each Myleran tablet contains the active ingredient, Busulfan.


    Do not take Myleran if you have not been definitively diagnosed with chronic myelogenous leukemia.

    Do not take Myleran if you are allergic to busulfan or any of the other ingredients. Discuss your allergies with your doctor.


    MYLERAN is a potent drug. It should not be used unless a diagnosis of chronic myelogenous leukemia has been adequately established and the responsible physician is knowledgeable in assessing response to chemotherapy.

    MYLERAN can induce severe bone marrow hypoplasia. Reduce or discontinue the dosage immediately at the first sign of any unusual depression of bone marrow function as reflected by an abnormal decrease in any of the formed elements of the blood. A bone marrow examination should be performed if the bone marrow status is uncertain.


    Tell your doctor about all the medications you take, including over-the-counter medications, vitamins, and supplements. Myerlan can interact with certain medications that can lead to unpleasant or dangerous reactions.

    Once you are prescribed and buy Myleran, it is important to know that Myleran may induce bone marrow failure which can lead to low blood cell counts. Exercise extreme caution if your bone marrow reserve has been affected.

    The use of Myleran can cause bronchopulmonary dysplasia with pulmonary fibrosis. Seek medical care immediately if you experience a cough, shortness of breath, and a fever.

    Myleran can cause cellular dysplasia in many organs, including the lungs. 

    Malignant tumors and acute leukemias have been observed in patients who took Myleran. 

    Suppression of the ovaries and the absence of menstruation with symptoms of menopause have been experienced in premenopasual patients who have received Myleran. 

    Male patients may experience sterility, testicular atrophy, and the absence of sperm with Myleran therapy.

    Hepatic veno-occlusive disease may occur with the use of Myleran, especially if taken with cyclophosphamide or other chemotherapeutic agents before bone marrow transplantation. Liver enzymes should be monitored.

    Cardiac tamponade has been seen in patients with thalassemia who have received Myleran and cyclophosphamide. 

    Tell your doctor if you are pregnant or plan to become pregnant. Myleran may cause harm to an unborn fetus.

    Tell your doctor if you are breastfeeding or plan to breastfeed. 

    Side Effects

    Side effects may occur with the use of Myleran, and some side effects can be severe. Myleran may cause:

    • Low blood counts
    • Infection
    • Vision problems
    • Respiratory problems
    • Nausea
    • Vomiting
    • Cough
    • Mouth sores
    • Skin redness, blistering, or peeling 
    • Fast heartbeat
    • Irregular heartbeat
    • Seizures
    • Swelling
    • Weakness or tiredness
    • Yellowing of the skin or eyes

    Tell your doctor right away if you experience side effects that are bothersome or won't go away.


    1. Myleran (busulfan) Prescribing Information. Research Triangle Park, NC: DSM Pharmaceuticals, Inc.; 2003.
    2. Myleran. GoodRx. Accessed January 3, 2022.

    Frequently Asked Questions about Myleran (Busulfan)

    What is Myleran (Busulfan)?

    Myleran (Busulfan) is a chemotherapy drug that is used to treat chronic myelogenous leukemia (CML) and other types of cancer.

    What is Myleran (Busulfan) used for?

    Myleran (Busulfan) is used to treat chronic myelogenous leukemia (CML) and other types of cancer.

    How does Myleran (Busulfan) work?

    Myleran (Busulfan) works by slowing or stopping the growth of cancer cells in the body.

    What are the side effects of Myleran (Busulfan)?

    The common side effects of Myleran (Busulfan) include nausea, vomiting, diarrhea, mouth sores, hair loss, and skin rash. Other side effects may include liver damage, lung damage, and infertility.

    How is Myleran (Busulfan) administered?

    Myleran (Busulfan) is administered orally in the form of tablets.

    What should I avoid while taking Myleran (Busulfan)?

    You should avoid drinking alcohol while taking Myleran (Busulfan) as it can increase the risk of liver damage. You should also avoid becoming pregnant or fathering a child while taking Myleran (Busulfan) as it can cause birth defects.

    What should I tell my healthcare provider before taking Myleran (Busulfan)?

    You should tell your healthcare provider if you have any allergies, liver disease, lung disease, or if you are pregnant or planning to become pregnant. You should also tell your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter drugs, vitamins, and herbal supplements.

    How long does it take for Myleran (Busulfan) to work?

    The time it takes for Myleran (Busulfan) to work varies depending on the type of cancer being treated and the individual patient. Your healthcare provider will be able to provide you with more information about how long it will take for Myleran (Busulfan) to work in your specific case.

    What happens if I miss a dose of Myleran (Busulfan)?

    If you miss a dose of Myleran (Busulfan), you should take it as soon as you remember. However, if it is almost time for your next dose, you should skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

    What should I do in case of an overdose of Myleran (Busulfan)?

    If you suspect an overdose of Myleran (Busulfan), you should contact your healthcare provider or seek emergency medical attention immediately. Overdose symptoms may include nausea, vomiting, diarrhea, mouth sores, hair loss, skin rash, liver damage, lung damage, and infertility.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1662

  • Product Reviews


Please wait while the page is loading. Do not hit refresh or the browser back button to avoid any loss of information.

If you have any questions or concerns, please contact our Customer Service team via the chat option on our website or calling us toll free at: 1-800-891-0844