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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

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Neoral Oral Solution (Cyclosporine)

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Brand

Neoral Oral Solution (Cyclosporine)

Prescription Required

Strength
Qty
100mg / ml 50ml

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  • Product Details

    Description

    Neoral oral solution is prescribed to prevent graft rejection in patients who have received liver, skin, kidney, heart, pancreas, small intestine, lung, or bone marrow transplant. Neoral should only be prescribed by healthcare providers experienced in transplant medicine.

    Neoral is a potent immunosuppressant that lowers a patient’s immune system activity to not attack the transplanted organ.

    Fact Table

    Formula

    C62H111N11O12

    License

    US FDA, EU EMA

    Bioavailability

    variable

    Legal status

    Rx-only

    Chemical Name

    Cyclosporine

    Elimination half-life

    variable (about 24 hours)

    Dosage (Strength)

    100mg/ml

    Pregnancy

    No Known Risk

    Brands

    Neoral

    Protein binding

    -

    PubChem CID

    5284373

    MedlinePlus

    a682116

    ChEBI

    8435

    ATC code

    a601207

    DrugBank

    DB00091

    KEGG

    D00184

    Routes of administration

    Oral

    Directions

    Take Neoral exactly as prescribed by your doctor. The dose may be changed based on your blood levels of cyclosporine.

    Never change the pharmacy you purchase without first discussing it with your transplant team.

    Never change your formulation of cyclosporine without discussing it with your transplant team.

    Ingredients

    The active ingredient in Neoral is cyclosporine.

    Interactions

    Neoral has many possible drug-drug interactions. Tell your transplant team about all drugs you are taking, including over-the-counter, herbals, and supplements.

    Common drug-drug interactions with Neoral include:

    • Allopurinol
    • Amiodarone
    • Amphotericin B
    • Azithromycin
    • Bosentan
    • Bromocriptine
    • Carbamazepine
    • Cimetidine
    • Ciprofloxacin
    • Clarithromycin
    • Colchicine
    • Diclofenac
    • Diltiazem
    • Erythromycin
    • Fenofibrate
    • Fluconazole
    • Gemfibrozil
    • Gentamicin
    • Itraconazole
    • Ketoconazole
    • Ketoconazole
    • Melphalan
    • Methotrexate
    • Methylprednisolone
    • Metoclopramide
    • Naproxen
    • Nefazodone
    • Nicardipine
    • Octreotide
    • Oral contraceptives
    • Orlistat
    • Oxcarbazepine
    • Phenobarbital
    • Phenytoin
    • Ranitidine
    • Rifampin
    • St. John's Wort
    • Sulindac
    • Tacrolimus
    • Terbinafine
    • Tobramycin
    • Trimethoprim-Sulfamethoxazole
    • Vancomycin
    • Verapamil
    • Voriconazole

    Drug-drug interactions may decrease the levels of Neoral in the body and lead to transplant rejection.

    Cautions

    Neoral can increase the risk of serious infection.

    Tell your doctor if you have a history of kidney or liver problems.

    Ask your doctor for a full list of side effects that applies to you.

    Side Effects

    Common side effects of Neoral include:

    • Abdominal distress
    • Diarrhea
    • Dyspepsia
    • Edema
    • Female genital tract disease
    • Gingival hyperplasia
    • Headache
    • Hirsutism
    • Hypertension
    • Increased serum creatinine
    • Increased serum triglycerides
    • Increased susceptibility to infection
    • Leg cramps
    • Nausea
    • Paresthesia
    • Renal insufficiency
    • Tremor
    • Upper respiratory tract infection
    • Urinary tract infection
    • Viral infection

    References

    Neoral Oral Solution [package insert]. East Hanover, NJ: Novartis; 2009.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 9367

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