A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Neoral Oral Solution (Cyclosporine)
Brand
Neoral Oral Solution (Cyclosporine)
Prescription Required
Strength
Qty
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Neoral oral solution is prescribed to prevent graft rejection in patients who have received liver, skin, kidney, heart, pancreas, small intestine, lung, or bone marrow transplant. Neoral should only be prescribed by healthcare providers experienced in transplant medicine.
Neoral is a potent immunosuppressant that lowers a patient’s immune system activity to not attack the transplanted organ.
Fact Table
Formula
C62H111N11O12
License
US FDA, EU EMA
Bioavailability
variable
Legal status
Rx-only
Chemical Name
Cyclosporine
Elimination half-life
variable (about 24 hours)
Dosage (Strength)
100mg/ml
Pregnancy
No Known Risk
Brands
Neoral
Protein binding
-
PubChem CID
5284373
MedlinePlus
a682116
ChEBI
8435
ATC code
a601207
DrugBank
DB00091
KEGG
D00184
Routes of administration
Oral
Directions
Take Neoral exactly as prescribed by your doctor. The dose may be changed based on your blood levels of cyclosporine.
Never change the pharmacy you purchase without first discussing it with your transplant team.
Never change your formulation of cyclosporine without discussing it with your transplant team.
Ingredients
The active ingredient in Neoral is cyclosporine.
Interactions
Neoral has many possible drug-drug interactions. Tell your transplant team about all drugs you are taking, including over-the-counter, herbals, and supplements.
Common drug-drug interactions with Neoral include:
Allopurinol
Amiodarone
Amphotericin B
Azithromycin
Bosentan
Bromocriptine
Carbamazepine
Cimetidine
Ciprofloxacin
Clarithromycin
Colchicine
Diclofenac
Diltiazem
Erythromycin
Fenofibrate
Fluconazole
Gemfibrozil
Gentamicin
Itraconazole
Ketoconazole
Ketoconazole
Melphalan
Methotrexate
Methylprednisolone
Metoclopramide
Naproxen
Nefazodone
Nicardipine
Octreotide
Oral contraceptives
Orlistat
Oxcarbazepine
Phenobarbital
Phenytoin
Ranitidine
Rifampin
St. John's Wort
Sulindac
Tacrolimus
Terbinafine
Tobramycin
Trimethoprim-Sulfamethoxazole
Vancomycin
Verapamil
Voriconazole
Drug-drug interactions may decrease the levels of Neoral in the body and lead to transplant rejection.
Cautions
Neoral can increase the risk of serious infection.
Tell your doctor if you have a history of kidney or liver problems.
Ask your doctor for a full list of side effects that applies to you.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 9367
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Prescription Required
