Neupogen (Filgrastim)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Prescription Required

  • Product Details

    Description

    Neupogen is a prescription febrile neutropenia prevention medication that is prescribed for people who are undergoing chemotherapy treatments and have low white blood cell counts. Filgrastim is a G-CSF class drug that works by stimulating bone marrow so that greater numbers of white blood cells are produced and mature faster into neutrophils that then go into the bloodstream to fight bacteria and reduce the risk of neutropenia infection during cancer treatment. Buy Neupogen from Canada Pharmacy and get the best price on it.

    Fact Table

    Formula

    C845H1343N223O243S9

    License

    US FDA, US DailyMed, EU EMA

    Bioavailability

    60 to 70%

    Legal status

    Rx-Only

    Chemical Name

    Filgrastim

    Elimination half-life

    3.5 hours

    Dosage (Strength)

    300mcg/mL, 480mcg/1.6mL

    Pregnancy

    Consult a healthcare provider for advice

    Brands

    Neupogen

    Protein binding

    Unknown

    PubChem CID

    Not available because this is not a discrete structure

    MedlinePlus

    a692033

    ChEBI

    Not Assigned

    ATC code

    L03AA02

    DrugBank

    DB00099

    KEGG

    D03235

    Routes of administration

    Intraveneous, subcutaneous

    Directions

    General:

    The Neupogen injection should be administered subcutaneously (under skin) daily and at the same time each day during a chemotherapy cycle, but should not be given anytime within 24 hours before or after a chemotherapy session.

    Possible injection sites are the upper arm, thigh (front of upper legs), buttocks, or stomach (abdomen), excluding a 2" radius around the navel.

    Administration:

    Remove syringe tray from carton and allow it to warm up at room temperature for 30 minutes before injection.

    Open tray by pulling back cover and use thumb and index finger to grab syringe from the tray.

    Along with the syringe, prepare the following materials that will also be needed for your injection:

    • Alcohol wipe
    • Cotton ball or gauze pad
    • Adhesive bandage
    • Sharps disposal container

    Clean administration site.

    Hold prefilled syringe by barrel and pull gray needle cap off.

    Confirm dosage (full / partial) indicated on syringe matches the dose you are to be taking.

    Point needle up and tap gently until air rises to the top.

    Push plunger rod up to the line on the barrel that matches your prescribed dose.

    Pinch injection site to create firm surface on the skin.

    Hold pinch while inserting needle into skin at 45 to 90 degrees.

    Push syringe plunger rod until it reaches bottom.

    Once injection is complete pull syringe out and away from skin.

    Pull orange safety guard over needle and have it click into position before disposing in sharps container.

    Ingredients

    The active ingredient in Neupogen is Filgrastim.

    Cautions

    Tell your doctor of any history of kidney dysfunction, sickle cell disorders, latex allergies, or if you are receiving radiation therapy before starting on Neupogen.

    Store Neupogen in a refrigerator between 36 and 46 degrees Fahrenheit (2-8 Celsius) and do not freeze.

    Women who are pregnant or breastfeeding should not use this medication unless their doctor approves it.

    Use of Neupogen can cause a serious lung problem (ARDS - acute respiratory distress syndrome) or capillary leak syndrome. Seek medical assistance immediately if you have fever, shortness of breath, stuffy or runny nose followed by tiredness, increased thirst, decreased urination following use of this medication.

    Spleen enlargement or a rupturing of the spleen may also be possible with the Neupogen injection, and you should seek medical assistance if you have pain in the left side of your upper stomach or in your left shoulder after giving yourself an injection.

    Keep out of reach of children even while refrigerated.

    Interactions

    Negative drug interactions are possible between Neupogen and other Rx medications, including acyclovir, albuterol, lorazepam, diphenhydramine, ciprofloxacin, dexamethasone, hydromorphone, gabapentin, furosemide, leucovorin, levofloxacin, levothyroxine, lorazepam, esomeprazole, omeprazole, ondansetron, oxycodone, pantoprazole, prednisone, prochlorperazine, lenalidomide, trazodone, and ondansetron.

    Tell your doctor of all medications you are currently taking before receiving a prescription and proceeding to buy Neupogen online.

    Side Effects

    Neupogen side effects are possible, and some users may experience fever, nosebleeds, cough, bone pain, breathing difficulties, anemia, diarrhea, headache, numbness, rash, or hair loss. If side effects are experienced it may be best to discontinue use and speak to your doctor again regarding neutropenia prevention medication alternatives.


    Frequently Asked Questions about Neupogen (Filgrastim)


    What is Neupogen used for?

    Neupogen (filgrastim) helps increase your white blood cell count, specifically neutrophils, which fight infections. It's used after treatments like chemotherapy or radiation that can lower your white blood cell levels.


    How is Neupogen given?

    It's usually injected under the skin (subcutaneously) or into a vein (intravenously). Your doctor will determine the best method and dosage for you.


    How long do I need to take Neupogen?

    The duration depends on your condition and why you're taking it. Some people need it for short periods after treatment, while others may need it long-term.


    What are the common side effects of Neupogen?

    Bone pain, muscle pain, headache, fatigue, nausea, and hair loss are common. Tell your doctor if any side effects bother you or worsen.


    Can I take Neupogen if I'm pregnant or breastfeeding?

    Talk to your doctor before taking Neupogen if you're pregnant or breastfeeding. Its safety in these situations is still being studied.


    Will Neupogen cure my cancer?

    No, Neupogen doesn't treat cancer itself. It only helps boost your white blood cells to fight off infections that may occur during cancer treatment.


    Does Neupogen increase the risk of infection?

    No, it actually helps prevent infections by raising your white blood cell count. However, be vigilant about hygiene and tell your doctor if you experience any fever or infection symptoms.


    Can I get vaccinated while taking Neupogen?

    Consult your doctor about specific vaccines. Some live vaccines may not be recommended while on Neupogen.


    What should I do if I miss a dose?

    Contact your doctor for guidance. Don't take a double dose to make up for a missed one.


    How much does Neupogen cost?

    The cost can vary depending on your insurance coverage and dosage. Talk to your doctor or pharmacist about estimated costs.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11520

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