What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Neupro Transdermal Patch (Rotigotine)
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Product Details
Description
The NEUPRO Transdermal Patch (Rotigotine) is a medicated patch used to treat Parkinson's disease and moderate-to-severe primary Restless Legs Syndrome. Parkinson's disease (PD) is a neurodegenerative disorder that can cause tremors, slow movement, stiffness, and balance problems.
Restless Legs Syndrome is a disorder that causes you to want to move your legs. As a result of long-term RLS, you may feel unpleasant sensations such as aching, burning, itching, throbbing, or tugging.
NEUPRO Transdermal Patch (Rotigotine) is classified as a dopamine agonist.
Fact Table
Formula
C19H25NOS
License
US DailyMed, EU EMA
Bioavailability
37%
Legal status
Rx-Only
Chemical Name
Rotigotine
Elimination half-life
5–7 hours
Dosage (Strength)
1mg - 8mg (24 hours patches)
Pregnancy
Consult Doctor
Brands
Neupro
Protein binding
92%
PubChem CID
57537
MedlinePlus
a607059
ChEBI
135351
ATC code
N04BC09
DrugBank
DB05271
KEGG
D05768
Routes of administration
Transdermal patch
Directions
For Parkinson's disease, NEUPRO Transdermal Patch (Rotigotine) dosages range from 2 mg/24 hours to 8 mg/24 hours.
For Restless Legs Syndrome, NEUPRO Transdermal Patch (Rotigotine) dosages range from 1 mg/24 hours to 3 mg/24 hours.
NEUPRO should be applied to clean, dry, and undamaged skin once a day. It should be held firmly in place for 30 seconds. The patch should not be placed where it could be rubbed by clothing. Do not place the patch on the same site of skin more than once every 14 days.
Ingredients
The active ingredient in the NEUPRO Transdermal Patch is rotigotine.
Cautions
NEUPRO contains sodium metabisulfite which can cause allergic reactions in people who are sensitive to sulfite.
Falling asleep or drowsiness during daily activities may occur.
Hallucinations or psychosis may occur.
A symptomatic drop in blood pressure upon sitting or standing up may occur, especially during dosage increases. Fainting may also occur.
An increase in blood pressure or heart rate may occur.
If you experience compulsive behaviors, consider decreasing the dose or stopping NEUPRO.
You may experience a very high fever and confusion if you suddenly stop NEUPRO or decrease the dose.
Withdrawal symptoms such as anxiety, depression, tiredness, trouble sleeping, sweating, and pain have been reported when decreasing dosages or after stopping NEUPRO.
Side Effects
If you experience any adverse effects while using the NEUPRO Transdermal Patch (Rotigotine), be sure to speak with your doctor. Common side effects of NEUPRO include:
- Application site reactions
- Anorexia
- Dizziness
- Drowsiness
- Dyskinesia
- Excessive sweating
- Headache
- Nausea
- Peripheral edema
- Sleep problems
- Vision problems
- Vomiting
References:
- NEUPRO Prescribing Information. Smyrna, GA: UCB, Inc., 2021.
- What Is Parkinson's? Parkinson's Foundation. Accessed October 20, 2021.
- Restless Legs Syndrome. Cleveland Clinic. Last reviewed January 24, 2020. Accessed October 20, 2021.
Frequently Asked Questions about Neupro Transdermal Patch (Rotigotine)
What is Neupro Transdermal Patch (Rotigotine) used for?
Neupro Transdermal Patch is a dopamine agonist used to treat Parkinson's disease and Restless Legs Syndrome (RLS). It works on the nervous system to alleviate symptoms of these conditions.
Can I get my Neupro Patch wet?
Yes, you can bathe, shower, or swim while wearing the Neupro Patch, but avoid hot baths as the heat may cause too much medicine to pass through your skin.
What if my Neupro Patch falls off?
If the patch falls off, apply a fresh one until your regular scheduled time, then place a new patch on a different skin part.
How long does it take for the Neupro Patch to start working?
The doctor will begin with a low dose and may change it weekly. It may take several weeks to find the dose that best controls your symptoms.
What should I avoid while taking Neupro?
Avoid driving or operating machinery until you know how Neupro affects you. Also, do not expose the patch to heat or wear it during MRI or cardioversion procedures.
How do I apply the Neupro Patch?
Apply the patch to a clean, dry, and hairless skin area. Press firmly for 30 seconds for good skin contact. Change the patch location daily and do not reuse the same location for 14 days.
Are there any side effects of Neupro Patch?
Common side effects include skin reactions at the application site, changes in blood pressure or heart rate, dizziness, sleepiness, and behavioral changes like increased urges (gambling, spending, eating) or hallucinations.
Can Neupro Patch be used in elderly patients?
While it is generally useful in elderly patients, they are more likely to develop hallucinations and should be used with caution.
What precautions should I take if I am pregnant or breastfeeding?
The medication may alter milk production or composition. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor.
How do I safely stop using the Neupro Patch?
Do not stop or change your treatment without consulting your doctor. Stopping suddenly may cause withdrawal symptoms.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 11660
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