Description
The NEUPRO Transdermal Patch (Rotigotine) is a medicated patch used to treat Parkinson's disease and moderate-to-severe primary Restless Legs Syndrome. Parkinson's disease (PD) is a neurodegenerative disorder that can cause tremors, slow movement, stiffness, and balance problems.
Restless Legs Syndrome is a disorder that causes you to want to move your legs. As a result of long-term RLS, you may feel unpleasant sensations such as aching, burning, itching, throbbing, or tugging.
NEUPRO Transdermal Patch (Rotigotine) is classified as a dopamine agonist.
Fact Table |
Formula |
C19H25NOS |
License |
US DailyMed, EU EMA |
Bioavailability |
37% |
Legal status |
Rx-Only |
Chemical Name |
Rotigotine |
Elimination half-life |
5–7 hours |
Dosage (Strength) |
1mg - 8mg (24 hours patches) |
Pregnancy |
Consult Doctor |
Brands |
Neupro |
Protein binding |
92% |
PubChem CID |
57537 |
MedlinePlus |
a607059 |
ChEBI |
135351 |
ATC code |
N04BC09 |
DrugBank |
DB05271 |
KEGG |
D05768 |
Routes of administration |
Transdermal patch |
Directions
For Parkinson's disease, NEUPRO Transdermal Patch (Rotigotine) dosages range from 2 mg/24 hours to 8 mg/24 hours.
For Restless Legs Syndrome, NEUPRO Transdermal Patch (Rotigotine) dosages range from 1 mg/24 hours to 3 mg/24 hours.
NEUPRO should be applied to clean, dry, and undamaged skin once a day. It should be held firmly in place for 30 seconds. The patch should not be placed where it could be rubbed by clothing. Do not place the patch on the same site of skin more than once every 14 days.
Ingredients
The active ingredient in the NEUPRO Transdermal Patch is rotigotine.
Cautions
NEUPRO contains sodium metabisulfite which can cause allergic reactions in people who are sensitive to sulfite.
Falling asleep or drowsiness during daily activities may occur.
Hallucinations or psychosis may occur.
A symptomatic drop in blood pressure upon sitting or standing up may occur, especially during dosage increases. Fainting may also occur.
An increase in blood pressure or heart rate may occur.
If you experience compulsive behaviors, consider decreasing the dose or stopping NEUPRO.
You may experience a very high fever and confusion if you suddenly stop NEUPRO or decrease the dose.
Withdrawal symptoms such as anxiety, depression, tiredness, trouble sleeping, sweating, and pain have been reported when decreasing dosages or after stopping NEUPRO.
Side Effects
If you experience any adverse effects while using the NEUPRO Transdermal Patch (Rotigotine), be sure to speak with your doctor. Common side effects of NEUPRO include:
- Application site reactions
- Anorexia
- Dizziness
- Drowsiness
- Dyskinesia
- Excessive sweating
- Headache
- Nausea
- Peripheral edema
- Sleep problems
- Vision problems
- Vomiting
References:
- NEUPRO Prescribing Information. Smyrna, GA: UCB, Inc., 2021.
- What Is Parkinson's? Parkinson's Foundation. Accessed October 20, 2021.
- Restless Legs Syndrome. Cleveland Clinic. Last reviewed January 24, 2020. Accessed October 20, 2021.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 11660