What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Neupro Transdermal Patch (Rotigotine)

Sezzle
Brand

Neupro Transdermal Patch (Rotigotine)

Prescription Required

Strength
Qty
1mg / 24 hours
2mg / 24 hours
3mg / 24 hours
4mg / 24 hours
6mg / 24 hours
8mg / 24 hours

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  • Product Details

    Description

    The NEUPRO Transdermal Patch (Rotigotine) is a medicated patch used to treat Parkinson's disease and moderate-to-severe primary Restless Legs Syndrome. Parkinson's disease (PD) is a neurodegenerative disorder that can cause tremors, slow movement, stiffness, and balance problems.

    Restless Legs Syndrome is a disorder that causes you to want to move your legs. As a result of long-term RLS, you may feel unpleasant sensations such as aching, burning, itching, throbbing, or tugging.

    NEUPRO Transdermal Patch (Rotigotine) is classified as a dopamine agonist.


    Fact Table

    Formula

    C19H25NOS

    License

    US DailyMed, EU EMA

    Bioavailability

    37%

    Legal status

    Rx-Only

    Chemical Name

    Rotigotine

    Elimination half-life

    5–7 hours

    Dosage (Strength)

    1mg - 8mg (24 hours patches)

    Pregnancy

    Consult Doctor

    Brands

    Neupro

    Protein binding

    92%

    PubChem CID

    57537

    MedlinePlus

    a607059

    ChEBI

    135351

    ATC code

    N04BC09

    DrugBank

    DB05271

    KEGG

    D05768

    Routes of administration

    Transdermal patch

    Directions

    For Parkinson's disease, NEUPRO Transdermal Patch (Rotigotine) dosages range from 2 mg/24 hours to 8 mg/24 hours.

    For Restless Legs Syndrome, NEUPRO Transdermal Patch (Rotigotine) dosages range from 1 mg/24 hours to 3 mg/24 hours.

    NEUPRO should be applied to clean, dry, and undamaged skin once a day. It should be held firmly in place for 30 seconds. The patch should not be placed where it could be rubbed by clothing. Do not place the patch on the same site of skin more than once every 14 days.

    Ingredients

    The active ingredient in the NEUPRO Transdermal Patch is rotigotine.

    Cautions

    NEUPRO contains sodium metabisulfite which can cause allergic reactions in people who are sensitive to sulfite.

    Falling asleep or drowsiness during daily activities may occur.

    Hallucinations or psychosis may occur.

    A symptomatic drop in blood pressure upon sitting or standing up may occur, especially during dosage increases. Fainting may also occur.

    An increase in blood pressure or heart rate may occur.

    If you experience compulsive behaviors, consider decreasing the dose or stopping NEUPRO.

    You may experience a very high fever and confusion if you suddenly stop NEUPRO or decrease the dose.

    Withdrawal symptoms such as anxiety, depression, tiredness, trouble sleeping, sweating, and pain have been reported when decreasing dosages or after stopping NEUPRO.

    Side Effects

    If you experience any adverse effects while using the NEUPRO Transdermal Patch (Rotigotine), be sure to speak with your doctor. Common side effects of NEUPRO include:

    • Application site reactions
    • Anorexia
    • Dizziness
    • Drowsiness
    • Dyskinesia
    • Excessive sweating
    • Headache
    • Nausea
    • Peripheral edema
    • Sleep problems
    • Vision problems
    • Vomiting

    References:

    1. NEUPRO Prescribing Information. Smyrna, GA: UCB, Inc., 2021.
    2. What Is Parkinson's? Parkinson's Foundation. Accessed October 20, 2021.
    3. Restless Legs Syndrome. Cleveland Clinic. Last reviewed January 24, 2020. Accessed October 20, 2021.

    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11660

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