What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Nucala Injection (Mepolizumab)
Prescription Required
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Product Details
Description
Nucala (mepolizumab) injection is used to treat:
- Adults and pediatric patients who are at least 6 years old and have severe asthma and an eosinophilic phenotype
- Adults who have chronic rhinosinusitis with nasal polyps
- Adults who have eosinophilic granulomatosis with polyangiitis
- Adults and pediatric patients who are least 12 years old and have had hypereosinophilic syndrome for 6 months or longer without an identifiable non-hematologic secondary cause
Nucala injections should not be used to treat sudden shortness of breath or asthma attacks.Nucala comes in 100 mg/mL single-dose prefilled autoinjector or single-dose prefilled syringe. It also comes as a 40 mg/0.4 mL single-dose prefilled syringe.
Directions
Use Nucala as instructed by your doctor. Any questions or concerns can be referred to your doctor or pharmacist.
Your doctor will determine an appropriate Nucala injection dose for you based on your age and condition being treated. In addition, your doctor or healthcare provider will instruct you on the proper administration of Nucala, how often you should administer it, and how long your treatment will last.
Nucala injection is usually given once every 4 weeks; it is injected underneath the skin of the upper arm, thigh, or abdomen.
Ingredients
Mepolizumab is the active ingredient contained in Nucala.
Citric acid monohydrate, EDTA disodium dihydrate, polysorbate 80, sodium phosphate dibasic heptahydrate, and sucrose are the inactive ingredients contained in the prefilled autoinjectors and prefilled syringes.
Contraindications
Do not use Nucala if you are allergic to any of its ingredients or excipients.
Cautions
- Before you begin treatment with Nucala, tell your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health conditions and past medical history
- Your pregnancy or breastfeeding status
- Allergic reactions, including anaphylaxis, angioedema, low blood pressure, hives, rash, and trouble breathing, can occur after Nucala use. Seek emergency care right away if you experience any of these reactions.
- Shingles can occur with Nucala use. Vaccination may be considered.
- When starting Nucala, do not abruptly stop taking systemic or inhaled corticosteroids. They should be gradually decreased.
- If you have a helminth infection, be sure you receive treatment before you begin using Nucala.
Side Effects
The most common side effects associated with Nucala injection include headache, injection site reaction, back pain, fatigue, pain and throat pain, and joint pain; however, these are not the only side effects that can occur. Contact your doctor right away if you have bothersome or persistent side effects.
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Reference:
- Nucala. Philadelphia, PA: GlaxoSmithKline LLC; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13771
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