A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Nucala is a monoclonal antibody that works by reducing levels of eosinophils (a type of white blood cell). High eosinophil levels can contribute to certain disorders. Nucala is used together with other medicines to help control severe asthma in adults and children who are at least 6 years old. Nucala is not a rescue medicine for asthma attacks.
You should not use Nucala if you are allergic to mepolizumab. Nucala is not approved for use in asthma by a child younger than 6 years old. Nucala should not be used to treat HES in anyone younger than 12 years old, or EPGA or CRSwNP in anyone younger than 18 years old.
Get emergency medical help if you have signs of an allergic reaction to Nucala: hives, rash; wheezing, chest tightness, difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: unusual pain or tiredness; burning or tingling anywhere in your body; or a red or blistering skin rash.