What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Olumiant (Baricitinib)

Sezzle
Brand

Olumiant (Baricitinib)

Prescription Required

Strength
Qty
2mg
4mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

Generic

What is a Generic?

Generic Equivalent - Olumiant (Baricitinib)

Prescription Required

Strength
Qty
2mg
4mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details

    Description

    Olumiant (baricitinib) is classified as a Janus kinase (JAK) inhibitor for the treatment of moderate to severe rheumatoid arthritis in adults who did not respond well or tolerate at least one tumor necrosis factor (TNF) blocker.

    Olumiant is available in 1 mg and 2 mg tablets.


    Fact Table

    Formula

    C16H17N7O2S

    License

    EU EMA, US DailyMed

    Bioavailability

    79%

    Legal status

    Rx-Only

    Chemical Name

    Baricitinib

    Elimination half-life

    12.5 hours

    Dosage (Strength)

    2mg, 4mg

    Pregnancy

    Contraindicated

    Brands

    Olumiant

    Protein binding

    50%

    PubChem CID

    44205240

    MedlinePlus

    a618033

    ChEBI

    95341

    ATC code

    L04AA37

    DrugBank

    DB11817

    KEGG

    D10308

    Routes of administration

    By mouth

    Directions

    The recommended dose is 2 mg by mouth once daily with or without food. 

    Your dose may be 1 mg by mouth once daily if you have kidney problems or are taking strong Organic Anion Transporter 3 (OAT3) inhibitors such as probenecid.

    Ingredients

    Each tablet contains the active ingredient, Baricitinib.

    Cautions

    WARNING: SERIOUS INFECTIONS, MORTALITY, MALIGNANCY, MAJOR ADVERSE CARDIOVASCULAR EVENTS (MACE), AND THROMBOSIS

    See full prescribing information for complete boxed warning.

    • Increased risk of serious bacterial, fungal, viral and opportunistic infections leading to hospitalization or death, including tuberculosis (TB). Interrupt treatment with OLUMIANT if serious infection occurs until the infection is controlled. Test for latent TB before and during therapy; treat latent TB prior to use. Monitor all patients for active TB during treatment, even patients with initial negative, latent TB tests. 
    • Higher rate of all-cause mortality, including sudden cardiovascular death with another Janus kinase inhibitor (JAK) vs. TNF blockers in rheumatoid arthritis (RA) patients. 
    • Malignancies have occurred in patients treated with OLUMIANT. Higher rate of lymphomas and lung cancers with another JAK inhibitor vs. TNF blockers in RA patients. 
    • Higher rate of MACE (defined as cardiovascular death, myocardial infarction, and stroke) with another JAK inhibitor vs. TNF blockers in RA patients. 
    • Thrombosis has occurred in patients treated with OLUMIANT. Increased incidence of pulmonary embolism, venous and arterial thrombosis with another JAK inhibitor vs. TNF blockers. 


    Tell your doctor if you have tuberculosis or if you have any other active infections or an infection that keeps coming back. Olumiant may increase the risk for serious infections and opportunistic infections, especially in those taking medications that suppress the immune system. Once you are prescribed and buy Olumiant, immediately tell your doctor if you develop a fever, cough, shortness of breath, muscle aches, diarrhea, stomach pain, tiredness, bloody phlegm, skin problems, sores on your body, weight loss, burning with urination, or the need to urinate more frequently.

    The risk of all-cause death is increased in patients who are at least 50 years old who have one or more risk factors for cardiovascular disease and are taking a JAK inhibitor. 

    Olumiant may increase your risk of developing certain cancers such as skin cancer, lung cancer, and lymphoma.

    Tell your doctor if you have heart problems or if you've ever had a stroke or heart attack. It is important to tell your doctor if you smoke. The risk of major cardiovascular events is increased in patients who are at least 50 years old who have one or more risk factors for cardiovascular disease and are taking a JAK inhibitor. Seek medical care immediately if you feel chest discomfort, nausea, vomiting, lightheadedness, shortness of breath, slurred speech, weakness in one part or on one side of your body, cold sweat, pain or discomfort in your arms, back, jaw, neck, or stomach, or tightness, heaviness, pain, or pressure in your chest, throat, neck, or jaw.

    Tell your doctor if you have had blood clots in your legs or lungs. Thrombosis has been reported with the use of Olumiant. Immediately tell your doctor if you experience leg pain, tenderness, or swelling, chest pain, or shortness of breath.

    Tell your doctor if you have stomach or intestinal problems. Tears in the stomach and intestines have occurred with Olumiant treatment. Immediately tell your doctor if you develop a fever, persistent stomach pain, and bowel changes.

    Abnormal blood counts may occur with Olumiant treatment.

    You should not receive live vaccines while being treated with Olumiant. 

    Olumiant may cause hypersensitivity reactions such as itching, swelling, or a rash. Some reactions may be more severe. Discuss your allergies with your doctor. 

    Tell your doctor if you are pregnant or plan to become pregnant, breastfeeding or plan to breastfeed.

    Olumiant may interact with certain medications that can lead to serious reactions. So, tell your doctor about all the medications that you take. 

    Side Effects

    Olumiant can cause side effects including:

    • Cold sores
    • Nausea
    • Shingles
    • Upper respiratory tract infections


    To buy Olumiant online at a competitive price with a valid prescription, visit Canada Pharmacy.

    References:

    1. Olumiant (baricitinib). Accessed January 3, 2022.
    2. Olumiant (baricitinib) Prescribing Information. Indianapolis, IN: Lilly USA, LLC; 2021.

    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13231

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