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Ongentys (Opicapone)
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Product Details
Description
Ongentys (opicapone) is used with levodopa/carbidopa to treat patients with Parkinson's Disease who are experiencing โoffโ episodes.
Directions
Follow the instructions that come with your prescription. If you have any questions or concerns, talk to your doctor or pharmacist.
Ongentys is available in 25 mg and 50 mg oral capsules.
Recommended dose: 50 mg by mouth once daily at bedtime. Food should be avoided for at least 1 hour before and 1 hour after taking Ongentys. The dose may be adjusted in patients with liver problems.
Ingredients
Each capsule contains opicapone, a selective and reversible catechol-O-methyltransferase (COMT) inhibitor.
Contraindications
Do not take Ongentys with non-selective monoamine oxidase (MAO) inhibitors. Ask your doctor if you are unsure whether or not you take MAO inhibitors.
Do not take Ongentys if you have ever had pheochromocytoma, paraganglioma, or other tumors that secrete catecholamines.
Cautions
- Before you start treatment with Ongentys, tell your doctor:
- About all the prescription and over-the-counter medications you take, including vitamins and herbal supplements.
- About your allergies.
- About your health conditions.
- If you are pregnant or planning to become pregnant. Ongentys may cause harm to an unborn baby.
- If you are breastfeeding or planning to breastfeed. It has not been determined whether or not Ongentys is transmitted through breast milk.
- You should avoid treatment with Ongentys if you have end-stage kidney disease.
- Ongentys can cause a rapid heart rate, arrhythmias, and blood pressure changes. Seek care right away if you experience any of these effects.
- Ongentys can cause you to feel sleepy or fall asleep, even during the daytime or during normal activities. You should not drive or operate machinery until you know how Ongentys affects you.
- Ongentys can cause low blood pressure. Your blood pressure should be monitored during treatment with Ongentys.
- Ongentys can cause or worsen dyskinesia, or sudden involuntary movements. Tell your doctor right away if this occurs.
- Ongentys can cause hallucinations or psychosis. Tell your doctor right away if these occur.
- Ongentys can cause impulsive behaviors or intense and uncontrollable urges to gamble, spend money, binge eat, and/or other urges. Tell your doctor right away if you experience these behaviors or urges.
- A sudden withdrawal or dose decrease can cause withdrawal-emergent hyperpyrexia and confusion with symptoms that may include a fever, stiff muscles, altered mental status, and autonomic instability. Ongentys should be slowly tapered or gradually withdrawn.
Side Effects
Ongentys can cause side effects, including sudden and involuntary movements, constipation, low blood pressure, weight loss, and an elevated blood creatine kinase. However, these are not all the possible side effects of Ongentys. Call your doctor right away if you develop side effects that are troublesome or won't go away.
Reference:
Ongentys (opicapone) capsules, for oral use. San Diego, CA: Neurocrine Biosciences, Inc.; 2020.
Popular Questions
Ongentys is available in 25 mg and 50 mg oral capsules. Offering different dosage options allows for personalized treatment plans that can be adjusted based on the patient's specific needs and medical conditions.
Ongentys (opicapone) is a medication used as an adjunct treatment for Parkinson's disease. It's important not to stop taking Ongentys abruptly without consulting a healthcare provider, as doing so could worsen symptoms or cause withdrawal effects. Always discuss any changes in medication with your doctor to ensure a safe and effective treatment plan.
Ongentys is used with levodopa/carbidopa to treat patients with Parkinson's Disease who are experiencing โoffโ episodes. This is valuable because it helps manage symptoms of Parkinson's, enhancing the effectiveness of existing treatments and improving the patient's quality of life.
The recommended dose is 50 mg by mouth once daily at bedtime. This schedule helps maintain consistent medication levels in the body, optimizing the management of Parkinson's symptoms.
Food should be avoided for at least 1 hour before and 1 hour after taking Ongentys. This is important because it ensures the medication is absorbed properly, maximizing its effectiveness.
Each capsule contains opicapone, a selective and reversible catechol-O-methyltransferase (COMT) inhibitor. This ingredient is crucial as it helps increase the levels of levodopa, reducing Parkinson's symptoms more effectively.
No, Ongentys should not be taken with non-selective monoamine oxidase (MAO) inhibitors. Avoiding this combination is essential to prevent severe interactions that could lead to harmful side effects.
You should not take Ongentys if you have had pheochromocytoma, paraganglioma, or other tumors that secrete catecholamines. This precaution helps avoid exacerbating these conditions, ensuring the patient's safety.
Ongentys can cause sudden and involuntary movements, constipation, low blood pressure, weight loss, and elevated blood creatine kinase. Being aware of these side effects allows patients and healthcare providers to monitor and manage any adverse reactions effectively.
View allCall your doctor right away if you develop side effects that are troublesome or won't go away. Prompt communication with a healthcare provider ensures that any issues are addressed quickly, maintaining the patient's health and treatment efficacy.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13648
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