What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Oseni (Alogliptin/pioglitazone)


Oseni (Alogliptin/pioglitazone)

Prescription Required

12.5mg / 15mg
25mg / 15mg
12.5mg / 30mg
25mg / 30mg
12.5mg / 45mg
25mg / 45mg

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Generic Equivalent - Oseni (Alogliptin/pioglitazone)

Prescription Required


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  • Product Details


    Oseni (alogliptin and pioglitazone) is a drug that is used with diet and exercise to treat type 2 diabetes in adults.

    Fact Table


    C18H21N5O2, C19H20N2O3S


    US DailyMed, US FDA, EU EMA



    Legal status


    Chemical Name


    Elimination half-life

    3–21 hours

    Dosage (Strength)

    12.5mg/45mg, 12.5mg/15mg, 25mg/15mg, 12.5mg/30 mg, 25mg/30mg, 25mg/45mg


    Consult Doctor



    Protein binding


    PubChem CID

    11450633, 4829


    a613026, a699016


    72323, 8228

    ATC code

    A10BH04, A10BG03


    DB11827, DB01261



    Routes of administration

    By mouth


    Oseni is available as a tablet in the following strengths:

    12.5 mg alogliptin/15 mg pioglitazone, 12.5 mg/30 mg pioglitazone, 12.5 mg alogliptin/45 mg pioglitazone

    25 mg alogliptin/15 mg pioglitazone, 25 mg alogliptin/30 mg pioglitazone, 25 mg alogliptin/45 mg pioglitazone 

    Your initial dose will depend on your current regimen and medical condition(s). The daily oral dose should not be more than alogliptin 25 mg/pioglitazone 45 mg. 

    Your dose may be adjusted if you have heart failure, kidney problems, or if you take certain medications such as gemfibrozil.

    Oseni can be taken with or without food. 


    The active ingredients in Oseni are alogliptin and pioglitazone. 


    Discuss your allergies with your doctor. Do not take Oseni if you are allergic to alogliptin, pioglitazone, or any of the other ingredients in Oseni.

    Do not take Oseni if you have been diagnosed with NYHA Class III or IV heart failure.



    See full prescribing information for complete boxed warning

    • Thiazolidinediones, including pioglitazone, cause or
      exacerbate congestive heart failure in some patients. 
    • After initiation of OSENI and after dose increases, monitor
      patients carefully for signs and symptoms of heart failure (e.g., excessive, rapid weight gain, dyspnea, and/or edema). If heart failure develops, it should be managed according to current standards of care and discontinuation or dose reduction of pioglitazone in OSENI must be considered.
    • OSENI is not recommended in patients with symptomatic heart failure.
    • Initiation of OSENI in patients with established New York Heart Association (NYHA) Class III or IV heart failure is contraindicated. 
    • Before you start taking Oseni, tell your doctor:
      • About any medications you take, including prescription, over-the-counter, vitamins, and supplements
      • About any health conditions you have
      • If you are pregnant or plan to become pregnant
      • If you are breastfeeding or plan to breastfeed
    • Oseni can worsen or cause congestive heart failure. Tell your doctor if you have trouble breathing with activity or when lying down, fatigue, weakness, swelling in the abdomen, legs, ankles, and feet, abnormal heart beat, a cough that won't go away, rapid weight gain, nausea, no appetite, problems concentrating, or chest pain. 
    • Oseni can cause acute pancreatitis. Seek medical care right away if you develop pain in your abdomen, pain that radiates from your abdomen to your back, tenderness of the abdomen, fever, quickened pulse, nausea, and vomiting.
    • Oseni can cause liver problems that can sometimes be fatal. 
    • Oseni can cause swelling.
    • Oseni can increase the risk for fractures in female patients.
    • Oseni can increase the risk for bladder cancer. If you have a history of bladder cancer, caution should be used. Do not take Oseni if you have active bladder cancer. 
    • Low blood sugar can occur when taking Oseni with insulin or other medications that can also lower your blood sugar. Monitor for signs of low blood sugar and treat your low blood sugar as your doctor has instructed.
    • Tell your doctor if you experience vision problems while taking Oseni. 

    Side Effects

    The most common side effects of Oseni include common cold, back pain, and upper respiratory tract infection. Contact your doctor right away if you develop troublesome or persistent side effects.


    1. Oseni Prescribing Information. Deerfield, IL: Takeda Pharmaceuticals America, Inc.; 2013.
    2. Heart failure. Mayo Clinic. December 10, 2021. Accessed February 4, 2022.
    3. Pancreatitis. Mayo Clinic. September 24, 2021. Accessed February 4, 2022.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13594

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