Palforzia
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Palforzia is used to reduce the symptoms of an allergic reaction to peanuts when accidentally exposed. However, it should not be used to emergently treat peanut allergies, including anaphylaxis.
Palforzia comes in powder for oral use contained in 0.5 mg, 1 mg, 10 mg, 20 mg, and 100 mg capsules or 300 mg sachets.
Directions
Use Palforzia as instructed by your doctor. If you have questions or concerns, contact your doctor or pharmacy.
Your doctor will determine appropriate Palforzia dosing for you.
The capsules should not be swallowed, and the powder should not be inhaled. Instead, open the capsule(s) or sachet and empty the contents onto refrigerated or room temperature semi solid food, mix thoroughly, then consume.
Ingredients
Peanut (Arachis hypogaea) Allergen Powder-dnfp is the active ingredient contained in Palforzia.
Microcrystalline cellulose, partially pregelatinized maize starch (0.5 mg, 1 mg, 10 mg, 20 mg and capsules only), magnesium stearate, and colloidal silicon dioxide are the inactive ingredients.
Contraindications
Palforzia should not be used in patients with uncontrolled asthma or with a history of eosinophilic esophagitis and other eosinophilic gastrointestinal disease.
Cautions
Palforzia is associated with the following FDA Boxed Warnings:
- Anaphylaxis, which can be life-threatening, can occur during Palforzia treatment
- Injectable epinephrine should be prescribed; patients should be instructed and trained on its appropriate use and to seek medical care immediately if used
- Palforzia should not be given to patients with uncontrolled asthma
- Dose adjustments may be needed after an anaphylactic reaction
- Patients should be observed during and after administration of the Initial Dose Escalation and the first dose of each Up-Dosing level, for at least one hour
- Palforzia can only be obtained through a restricted program known as the Palforzia REMS
- Before you are prescribed Palforzia, discuss the following with your doctor:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health conditions and past medical history
- If you are pregnant or breastfeeding
Side Effects
Common Palforzia side effects include abdominal pain, vomiting, nausea, itching of the mouth, numbness of the mouth, throat irritation, cough, runny nose, sneezing, throat tightness, wheezing, shortness of breath, itching, hives, anaphylactic reaction, and ear itchiness. If you experience side effects that bother you or won’t go away, call your doctor immediately.
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Reference:
- Palforzia. Brisbane, CA: Aimmune Therapeutics, Inc.; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13915
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