What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Permitil (Fluphenazine)
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Product Details
Description
Fluphenazine is a First Generation Antipsychotic (FGA) used for the treatment of mental health disorders. Examples include bipolar disorder, schizophrenia, and schizoaffective disorder. It also has usage in the management of tics in people with Tourette’s syndrome.
Fluphenazine is a piperazine phenothiazine FGA that works by increasing dopamine levels in certain areas of the brain. Regulating dopamine levels can improve psychotic symptoms.
Directions
The dosage is 2.5-10 mg by mouth divided into three or four dosages. Some patients may require much higher dosages, like 40 mg daily.
Ingredients
The active ingredient is fluphenazine.
Interactions
The most common drug-drug interactions may include:
- Aclidinium
- Aminolevulinic Acid
- Azelastine
- Bromopride
- Bromperidol
- Cabergoline
- Cimetropium
- Disulfiram
- Eluxadoline
- Flunarizine
- Glycopyrrolate
- Glycopyrronium
- Ipratropium
- Kratom
- Levosulpiride
- Methotrimeprazine
- Metoclopramide
- Olopatadine
- Ornidazole
- Orphenadrine
- Oxatomide
- Oxomemazine
- Paraldehyde
- Piribedil
- Potassium Chloride
- Potassium Citrate
- Pramlintide
- Revefenacin
- Saquinavir
- Secnidazole
- Sulpiride
- Thalidomide
- Tiotropium
- Triptorelin
- Umeclidinium
Cautions
Tell your doctor if you have a history of heart conditions before starting this drug.
Long-term usage of FGA increases the risk of extrapyramidal symptoms (EPS).
Fluphenazine has a higher risk of causing central nervous system (CNS) depression.
Ask your doctor and pharmacist for a complete list of precautions.
Side Effects
Common adverse reactions include
- Abnormal hepatic function tests
- Agranulocytosis
- Altered cerebrospinal proteins
- Amenorrhea
- Angioedema
- Asthma
- Atrioventricular block
- Bizarre dream
- Bladder paralysis
- Bradycardia
- Brain edema
- Cataract
- Corneal opacity
- ECG changes
- Eczema
- EEG pattern changes
- Eosinophilia
- Erythema of skin
- Excitement
- Exfoliative dermatitis
- Extrapyramidal reaction
- Fecal impaction
- Galactorrhea not associated with childbirth
- Glaucoma
- Gynecomastia
- Hypertension
- Hypotension
- Immune thrombocytopenia
- Impotence
- Increased libido
- Increased serum prolactin
- Jaundice
- Laryngeal edema
- Leukopenia
- Lupus-like syndrome
- Maculopathy
- Menstrual disease
- Nasal congestion
- Neuroleptic malignant syndrome
- Neutropenia
- Nonthrombocytopenic purpura
- Pancytopenia
- Paralytic ileus
- Peripheral edema
- Priapism
- Pruritus
- Restlessness
- Rhabdomyolysis
- Seborrhea
- Skin photosensitivity
- Skin pigmentation
- Tachycardia
- Urticaria
- Weight changes
- Withdrawal syndrome
References
Fluphenazine Hydrochloride [package insert]. Philadelphia, PA: Lannett Company, Inc.; 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 5400
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