What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Prednefrin Forte Eye drops (Prednisolone Acetate / Phenylephrine Hydrochloride)

Also Known as Pred Forte


Prednefrin Forte Eye drops (Prednisolone Acetate / Phenylephrine Hydrochloride)

Prescription Required

10mg / 1.2mg 10ml

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  • Product Details


    Prednefrin Forte (phenylephrine hydrochloride, prednisolone acetate) is an eye drop used to treat severe non infectious eye pain, swelling, and redness.

    Fact Table




    US DailyMed, EU EMA



    Legal status


    Chemical Name

    Prednisolone Acetate / Phenylephrine Hydrochloride

    Elimination half-life

    2–3.5 hours

    Dosage (Strength)

    10mg / 1.2mg 10ml


    Consult Doctor


    Prednefrin Forte Eye drops

    Protein binding


    PubChem CID






    ATC code






    Routes of administration



    The usual dosage is to place one to two drops in the affected eye(s) two to four times a day. Once you are prescribed and buy Prednefrin Forte, your doctor may instruct you to place 2 drops every hour for the first 24 to 48 hours of treatment.

    Do not stop using Prednefrin Forte unless your doctor tells you to.


    The active ingredients in Prednefrin Forte include Prednisolone acetate and Phenylephrine hydrochloride.


    Do not use Prednefrin Forte if you have an acute untreated purulent infection, ocular tuberculosis, fungal eye infection, mycobacterial eye infection, or narrow angle glaucoma.

    Do not use Prednefrin Forte if you are allergic to prednisolone acetate, phenylephrine hydrochloride, benzalkonium chloride, or any of the other ingredients. Talk to your doctor about your allergies.


    Prednefrin Forte contains a corticosteroid which may mask, enhance, or activate an acute untreated infection.

    Secondary eye infections may develop with long-term use of Prednefrin Forte.

    Corneal fungal infections may develop with long-term use of Prednefrin Forte.

    If you have stromal Herpes simplex, Prednefrin Forte can lengthen the course or exacerbate viral eye infections. Caution should be used.

    Prolonged use of Prednefrin Forte may increase your risk for glaucoma or posterior subcapsular cataracts.

    Do not use Prednefrin Forte for more than 10 days unless your doctor instructs you to do so and with regular intraocular pressure checks.

    Perforation of eye tissues may occur with Prednefrin Forte, especially if you have a thin cornea.

    Using Prednefrin Forte after cataract surgery may prolong healing time and increase the risk of bleb formation.

    Prednefrin Forte contains sodium metabisulfite. Discuss your allergies with your doctor as allergic reactions may occur in those who are sensitive to sulfite.

    Tell your doctor if you experience eye pain or vision changes. Stop using Prednefrin Forte and contact your doctor right away if you experience eye irritation and redness for more than 72 hours. 

    You should remove your contact lenses before instilling Prednefrin Forte eye drops. You may reinsert your contacts after 15 minutes following administration.

    If you are using more than one eye drop, you should wait at least 5 minutes before using the second eye drop.

    Tell your doctor about any medications you are taking, including prescription and over-the-counter medications.

    Your doctor should know if you are pregnant or plan to become pregnant.

    Tell your doctor if you are breastfeeding or plan to breastfeed.

    Side Effects

    Prednefrin Forte eye drops may cause side effects, including:

    • Dry eye
    • Eye discharge
    • Eye irritation
    • Eye infections
    • Eye pain
    • Cataract formation
    • Increased eye pressure
    • Increased tear flow
    • Itchy eye
    • Red eye
    • Perforation of eye tissues
    • Pupil dilation
    • Foreign body sensation
    • Vision problems
    • Rash
    • Headache
    • Altered taste

    Contact your doctor right away if you experience any side effects while using Prednefrin Forte eye drops.


    1. Prednefrin Forte Prescribing Information. Strawberry Hills, NSW: NPS MedicineWise; 2018. 
    2. Prednefrin Forte Consumer Medicine Information. Gordon, NSW: Allergan Australia Pty Ltd; 2017. 

    Frequently Asked Questions about Prednefrin Forte Eye Drops

    What are Prednefrin Forte Eye Drops used for?

    Prednefrin Forte is used to treat severe non-infectious inflammation of the eye, including conditions like uveitis, iritis, and scleritis. It can also be used for persistent eye allergies and inflammation after surgery.

    How do Prednefrin Forte Eye Drops work?

    Prednisolone acetate: a corticosteroid that reduces inflammation, swelling, and redness.
    Phenylephrine hydrochloride: a decongestant that shrinks swollen blood vessels in the eye, reducing redness and discomfort.

    How often and for how long should I use Prednefrin Forte Eye Drops?

    Your doctor will determine the exact dosage and duration of treatment based on your condition. Typically, it's 1-2 drops 2-4 times daily, with a possible increase to 2 drops hourly for the first 24-48 hours. Don't stop using it suddenly even if you feel better, as your doctor needs to monitor your progress.

    Can I use Prednefrin Forte Eye Drops if I'm pregnant or breastfeeding?

    Talk to your doctor before using Prednefrin Forte if you're pregnant or breastfeeding. The safety of its use during these times isn't fully established.

    Does Prednefrin Forte Eye Drops interact with other medications?

    Yes, it can interact with certain medications, including eye drops, glaucoma medications, and blood pressure medications. Tell your doctor about all medications you're taking before starting Prednefrin Forte.

    How should I store Prednefrin Forte Eye Drops?

    Store it at room temperature, away from light and heat. Do not refrigerate or freeze. Don't touch the dropper tip and keep the bottle tightly closed after use.

    Can I wear contact lenses while using Prednefrin Forte Eye Drops?

    No, discontinue wearing contact lenses while using Prednefrin Forte and for a few days after stopping it. Consult your doctor about when it's safe to resume wearing them.

    What should I do if I miss a dose of Prednefrin Forte Eye Drops?

    If you miss a dose, simply take it as soon as you remember. Do not take a double dose to make up for the missed one.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13232

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