What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Prolensa (Bromfenac ophthalmic solution)
Prescription Required
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Product Details
Description
Prolensa is a prescription eye medication used for the prevention of inflammation after cataract surgery. It is prescribed for short-term prophylaxis.
Prolensa is a non-steroidal anti-inflammatory drug (NSAIDs) that works to reduce the symptoms of inflammation, pain, redness, and itching. It works by preventing the formation of prostaglandins, which are chemical signals of the immune system.
Fact Table
Formula
C15H12BrNO3
License
US FDA, EU EMA
Bioavailability
87%
Legal status
Rx-only
Chemical Name
Bromfenac
Elimination half-life
1.4 hours
Dosage (Strength)
0.07% 3ml
Pregnancy
Consult Doctor
Brands
Bromday, Prolensa
Protein binding
99.8%
PubChem CID
60726
MedlinePlus
a611018
ChEBI
240107
ATC code
S01BC11
DrugBank
DB00963
KEGG
D07541
Routes of administration
Eye drops
Directions
Take Prolensa exactly as directed by your doctor. It is typically started 1 day before cataract surgery and continues for 14 days after surgery. Your doctor may decide it needs to be continued for a longer period.
Wash hands prior to use of this product.
If you wear contact lenses, remove them 10 minutes before applying the eye drops. If you are using other eye drops, wait 5 minutes between the application of each drug.
Ingredients
The active ingredient in Prolensa is Bromfenac.
Interactions
The most common drug-drug interactions with this drug can include:
- Bimatoprost
- Dexamethasone
- Fluocinolone
- Fluorometholone
- Latanoprost
- Latanoprostene
- Loteprednol
- Prednisolone
- Tafluprost
- Travoprost
Cautions
Tell your doctor if you are taking Aspirin or other drug products that contain NSAIDs.
Do not touch the tip of the eyedropper to the surface of your eye. Doing so can lead to contamination of the bottle and eye infection.
Long-term use may cause corneal thinning and loss of vision. Do not use for longer than directed.
Healing may be delayed while taking this medication.
Side Effects
Adverse effects from Prolensa may include:
- Abnormal sensation in eyes
- Anterior chamber inflammation
- Conjunctival hyperemia
- Corneal erosion
- Corneal perforation
- Corneal thinning
- Epithelial keratopathy
- Eye irritation
- Eye pain
- Eye pruritus
- Eye redness
- Headache
- Iritis
- Ocular hypertension
- Prolonged bleeding time
- Vitreous opacity
- Wound healing impairment
References
Prolensa. Tampa, FL: Bausch & Lomb; 2013.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13589
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