What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Prolensa (Bromfenac ophthalmic solution)
Prescription Required
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Product Details
Description
Prolensa is a prescription eye medication used for the prevention of inflammation after cataract surgery. It is prescribed for short-term prophylaxis.
Prolensa is a non-steroidal anti-inflammatory drug (NSAIDs) that works to reduce the symptoms of inflammation, pain, redness, and itching. It works by preventing the formation of prostaglandins, which are chemical signals of the immune system.
Fact Table
Formula
C15H12BrNO3
License
US FDA, EU EMA
Bioavailability
87%
Legal status
Rx-only
Chemical Name
Bromfenac
Elimination half-life
1.4 hours
Dosage (Strength)
0.07% 3ml
Pregnancy
Consult Doctor
Brands
Bromday, Prolensa
Protein binding
99.8%
PubChem CID
60726
MedlinePlus
a611018
ChEBI
240107
ATC code
S01BC11
DrugBank
DB00963
KEGG
D07541
Routes of administration
Eye drops
Directions
Take Prolensa exactly as directed by your doctor. It is typically started 1 day before cataract surgery and continues for 14 days after surgery. Your doctor may decide it needs to be continued for a longer period.
Wash hands prior to use of this product.
If you wear contact lenses, remove them 10 minutes before applying the eye drops. If you are using other eye drops, wait 5 minutes between the application of each drug.
Ingredients
The active ingredient in Prolensa is Bromfenac.
Interactions
The most common drug-drug interactions with this drug can include:
- Bimatoprost
- Dexamethasone
- Fluocinolone
- Fluorometholone
- Latanoprost
- Latanoprostene
- Loteprednol
- Prednisolone
- Tafluprost
- Travoprost
Cautions
Tell your doctor if you are taking Aspirin or other drug products that contain NSAIDs.
Do not touch the tip of the eyedropper to the surface of your eye. Doing so can lead to contamination of the bottle and eye infection.
Long-term use may cause corneal thinning and loss of vision. Do not use for longer than directed.
Healing may be delayed while taking this medication.
Side Effects
Adverse effects from Prolensa may include:
- Abnormal sensation in eyes
- Anterior chamber inflammation
- Conjunctival hyperemia
- Corneal erosion
- Corneal perforation
- Corneal thinning
- Epithelial keratopathy
- Eye irritation
- Eye pain
- Eye pruritus
- Eye redness
- Headache
- Iritis
- Ocular hypertension
- Prolonged bleeding time
- Vitreous opacity
- Wound healing impairment
References
Prolensa. Tampa, FL: Bausch & Lomb; 2013.
Frequently Asked Questions about Prolensa
What is Prolensa?
Prolensa is a brand name for the medication bromfenac ophthalmic solution. It is a non-steroidal anti-inflammatory drug (NSAID) used to reduce inflammation and pain in the eye following cataract surgery.
How does Prolensa work?
Prolensa works by inhibiting the production of certain substances in the eye that cause inflammation and pain. By reducing inflammation, it helps improve comfort and vision after cataract surgery.
Is Prolensa available over the counter?
No, Prolensa is not available over the counter. It is a prescription medication, which means you need a doctor's prescription to obtain it.
How should I use Prolensa eye drops?
Prolensa eye drops are typically used as directed by your eye surgeon. The usual dosage is one drop in the affected eye(s) once daily, starting one day before cataract surgery and continuing for several weeks after the procedure.
When should I use Prolensa?
Prolensa is used before and after cataract surgery to reduce inflammation and pain. It should be administered according to the specific instructions provided by your eye surgeon.
Can I wear contact lenses while using Prolensa?
You should avoid wearing contact lenses while using Prolensa, especially during the period immediately following cataract surgery. Your eye surgeon will advise you on when it is safe to resume wearing contact lenses.
Are there any side effects associated with Prolensa?
Like all medications, Prolensa can cause side effects. Common side effects may include eye irritation, burning, stinging, or blurred vision. If you experience severe eye pain, vision changes, or signs of an allergic reaction, seek medical attention immediately.
Can children use Prolensa?
Prolensa is typically prescribed for adults undergoing cataract surgery. Its use in children should be determined by a healthcare provider based on specific clinical needs.
Is Prolensa safe during pregnancy or while breastfeeding?
It is essential to discuss the use of Prolensa with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They can help assess the potential risks and benefits in your particular situation.
How should I store Prolensa eye drops?
Prolensa should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use, and ensure it is out of the reach of children.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13589
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