What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Qbrelis (Lisinopril)
Prescription Required
We don't have this generic product yet!
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
-
Product Details
Description
Qbrelis is a liquid formulation of lisinopril, a medication prescribed to treat high blood pressure and heart failure. High blood pressure is a chronic health condition that contributes to fatal heart conditions like myocardial infarction. Heart failure is when the heart cannot pump enough blood for the body's needs.
It works by preventing the conversion of Angiotensin I to Angiotensin II. Ultimately it causes the blood vessels to relax, lowering blood pressure.
Fact Table
Formula
C21H31N3O5
License
US FDA, EU EMA
Bioavailability
25%
Legal status
Rx-only
Chemical Name
Lisinopril
Elimination half-life
12 hours
Dosage (Strength)
1mg
Pregnancy
Not recommended
Brands
Qbrelis
Protein binding
0
PubChem CID
5362119
MedlinePlus
a692051
ChEBI
43755
ATC code
C09AA03
DrugBank
DB00722
KEGG
D00362
Routes of administration
By mouth
Directions
Qbrelis is usually started at 10 mg by mouth once daily. It can be taken with or without food at the same time each day.
The effective dose ranges from 2.5-40 mg by mouth once daily.
Ingredients
The active ingredient in Qbrelis is lisinopril.
Interactions
Qbrelis has several drug interactions that can decrease blood pressure to dangerously low levels. Tell your healthcare team if you are taking any of the following:
- Aliskiren
- Amifostine
- Bromperidol
- Candesartan
- Grass pollen allergen extract
- Irbesartan
- Iron dextran complex
- Lanthanum
- Lithium
- Losartan
- Obinutuzumab
- Olmesartan
- Sacubitril
- Sodium phosphates
- Telmisartan
- Urapidil
- Valsartan
Cautions
Qbrelis can affect kidney function, especially when taking it for the first time. Tell your doctor if you have a history of kidney dysfunction.
Use caution if you have a history of hyperkalemia (abnormally high potassium levels).
This medication should not be used by people with a history of angioedema.
Monitor liver function when taking this drug.
Side Effects
Common adverse reactions to this drug can include:
- Alopecia
- Altered sense of smell
- Arthralgia
- Arthritis
- Asthenia
- Blurred vision
- Bone marrow depression
- Constipation
- Cough
- Diabetes mellitus
- Diaphoresis
- Diarrhea
- Diplopia
- Dizziness
- Dysgeusia
- Eosinophilia
- Erythema of skin
- Fatigue
- Fever
- Flatulence
- Flushing
- Gout
- Hemolytic anemia
- Hyperkalemia
- Hypotension
- Impotence
- Increased blood urea nitrogen
- Increased erythrocyte sedimentation rate
- Increased serum creatinine
- Leukocytosis
- Leukopenia
- Myalgia
- Neutropenia
- Orthostatic hypotension
- Pancreatitis
- Paresthesia
- Photophobia
- Positive ANA titer
- Pruritus
- Psydolymphoma
- Renal insufficiency
- Skin photosensitivity
- Skin rash
- Stevens-Johnson syndrome
- Syncope
- Thrombocytopenia
- Tinnitus
- Toxic epidermal necrolysis
- Urticaria
- Vasculitis
- Vertigo
- Vision loss
- Xerostomia
References
Qbrelis. Greenwood Village, CO: Silvergate Pharmaceuticals, Inc; 2016.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13621
-
Product Reviews
