What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Qtern (Dapagliflozin / Saxagliptin)
Prescription Required
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Product Details
Description
Qtern is made of two medications: dapagliflozin (SGLT2 inhibitor) and saxagliptin (DPP-4 inhibitor). Qtern (dapagliflozin and saxagliptin) is used to help lower the A1C in patients with type 2 diabetes.
Qtern is available in two tablet strengths:
- 5 mg dapagliflozin/5 mg saxagliptin
- 10 mg dapagliflozin/5 mg saxagliptin
Fact Table
Formula
C21H25ClO6•C3H8O2•H2O
License
US DailyMed
Bioavailability
78%
Legal status
Rx-Only
Chemical Name
Dapagliflozin/saxagliptin
Elimination half-life
12.9 hours
Dosage (Strength)
10mg/5mg
Pregnancy
Not recommended
Brands
Qtern
Protein binding
91%
PubChem CID
124219523
MedlinePlus
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ChEBI
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ATC code
A10BD21
DrugBank
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KEGG
D10826
Routes of administration
By mouth
Directions
Qtern should be taken by mouth once daily in the morning. It can be taken with or without food. The tablet should be swallowed. It should not be crushed, cut, or chewed.
Ingredients
The active ingredients contained in Qtern are Dapagliflozin and Saxagliptin.
Contraindications
Do not take Qtern if you are allergic to dapagliflozin or saxagliptin. Discuss your allergies with your doctor before starting Qtern.
Qtern should not be taken if you have moderate to severe kidney impairment, end-stage renal disease, or if you are on dialysis.
Cautions
Tell your doctor about all the medications you take, including prescription and over-the-counter medications, vitamins, and supplements.
Once you are prescribed and buy Qtern, then Qtern may cause pancreatitis. Tell your doctor if you drink alcohol or if you have ever had pancreatitis, gallstones, or high triglycerides. Seek medical care right away if you develop severe stomach pain that persists.
Qtern may cause heart failure. Tell your doctor if you have heart problems or kidney problems. Seek medical care right away if you have trouble breathing, swelling in your feet, ankles, or legs, rapid weight gain, or unusual tiredness.
This medication may cause dehydration, which can make you feel dizzy or weak. Tell your doctor if you have blood pressure problems, kidney problems, or if you are on a low-salt diet.
Qtern may cause ketoacidosis. Seek medical care right away if you experience nausea, tiredness, vomiting, stomach pain, and trouble breathing.
Qtern may cause kidney problems. Seek medical care right away if you are unable to eat or drink, if you lose liquids, or if you've been in the heat for a long time.
Qtern may cause urinary tract infections. Tell your doctor right away if you experience burning when urinating, frequent urination, the need to urinate immediately, pelvic pain, or blood in your urine.
This medication may cause low blood sugar levels, especially if you take another medicine that can cause low blood sugar. Be aware of the symptoms of low blood sugar such as sweating, nervousness, dizziness, fast heartbeat, hunger, headache, confusion, mood changes, irritability, vision changes, or weakness. Treat your low blood sugar as your doctor has instructed.
Qtern may cause bacterial skin infections around the genitals. Seek medical care right away if you develop a fever, weakness, or tiredness and if you have skin tenderness, swelling, or redness.
This medication may cause vaginal yeast infections. Tell your doctor if you develop vaginal odor, discharge, or itching.
Qtern may cause penile yeast infections. Tell your doctor if you develop penile redness, itching, or swelling, rash, odorous discharge, or pain.
Qtern may cause joint pain. Tell your doctor if you develop severe pain in your joints.
Qtern may cause a skin reaction called bullous pemphigoid. Seek medical care right away if you develop skin blisters or breakdown.
Tell your doctor if you are pregnant or plan to become pregnant and your doctor should know if you are breastfeeding or plan to breastfeed.
Side Effects
Qtern can cause side effects. The most common include:
- Abnormal amounts of fats in the blood
- Upper respiratory tract infection
- Urinary tract infection
References:
- Qtern Prescribing Information. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020.
- Important Safety Information for Qtern. Accessed January 4, 2022.
Frequently Asked Questions about Qtern
What is Qtern?
Qtern is a prescription medication used to improve blood sugar control in adults with type 2 diabetes. It combines two drugs: dapagliflozin (SGLT-2 inhibitor) and saxagliptin (DPP-4 inhibitor).
Is Qtern right for me?
Only a doctor can decide if Qtern is right for you. Consult your doctor if you have uncontrolled type 2 diabetes, even if you're taking other diabetes medications. Qtern is not for everyone, especially if you have kidney problems, diabetic ketoacidosis, or severe liver problems.
How do I take Qtern?
Take Qtern as directed by your doctor, usually one tablet once daily with or without food in the morning. Swallow the tablet whole, do not crush, cut, or chew it.
What are the side effects of Qtern?
Common side effects include urinary tract infections, genital yeast infections, vaginal yeast infections, increased urination, and low blood sugar. Tell your doctor if any side effects become severe or bothersome.
Can I take Qtern with other medications?
Tell your doctor about all other medications you take, including over-the-counter drugs and supplements. Some medications can interact with Qtern, potentially causing harm.
Does Qtern cause weight loss?
Some people may experience weight loss while taking Qtern, but this is not a primary objective of the medication. Focus on maintaining a healthy diet and exercise routine for managing weight alongside diabetes.
Does Qtern cure diabetes?
No, Qtern does not cure diabetes, but it can help manage blood sugar levels and prevent complications.
How long does it take for Qtern to work?
You may see some improvement in blood sugar control within a few weeks of starting Qtern, but it may take several months to see the full benefit.
What should I do if I miss a dose of Qtern?
Take the missed dose as soon as you remember, unless it is nearly time for your next dose. Do not take a double dose.
What if I have more questions about Qtern?
Always consult your doctor or pharmacist for any questions or concerns you may have about Qtern.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13233
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