What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Rapamune (Sirolimus)


Rapamune (Sirolimus)






Generic Equivalent - Rapamune (Sirolimus)



Prescription Required

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    This medicine is an immunosuppressant used to prevent organ rejection after a kidney transplant. It may also be used to treat other conditions as determined by your doctor.


    Follow the directions for using this medicine provided by your doctor. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine. THIS MEDICINE MAY BE TAKEN on an empty stomach or with food. Always take it the same way, either with food or on an empty stomach. TAKE THIS MEDICINE at the same time each day. IF YOU ARE ALSO TAKING CYCLOSPORINE, take this medicine 4 hours after your cyclosporine dose unless otherwise directed by your doctor. DO NOT EAT GRAPEFRUIT OR DRINK GRAPEFRUIT JUICE AT ANY TIME WHILE TAKING THIS MEDICINE. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed and light-resistant container, away from heat and light. Protect from direct sunlight. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.


    WARNING This medicine may make you more likely to develop an infection or certain types of cancer (e.g., lymphoma). Notify your doctor immediately if you develop any signs of infection such as fever, chills, sore throat, white patches in your mouth or a change in vaginal discharge. Also notify your doctor immediately if you have unusual lumps, swollen glands, unusual sweating or unexplained weight loss. When sirolimus has been used in liver translpants, an infrequent but potentially fatal liver problem has occurred (hepatic artery thrombosis). Use of this medication to prevent rejection of liver transplants is not recommended. Notify your doctor immediately if you develop dark urine, stomach pain, yellowing eyes or skin, extreme fatigue, or nausea. When sirolimus has been used in lung transplants, an infrequent but potentially fatal lung problem has occurred (bronchial anastamotic dehiscence). Use of this medication to prevent rejection of lung transplants is not recommended. Notify your doctor immediately if you develop difficulty breathing. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE astemizole or terfenadine while you are taking this medicine. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking a macrolide antibiotic, an azole antifungal drug, HIV protease inhibitors, quinupristin, dalfopristin, diltiazem, rifampin, a nonsteroidal anti-inflammatory drug (NSAID), calcineurin inhibitors (such as tacrolimus), or St. Johns wort. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

    Product Code : 9740

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