A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Rapamune (Sirolimus)
Brand
Rapamune (Sirolimus)
Prescription Required
Strength
Qty
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Generic
Generic Equivalent - Rapamune (Sirolimus)
Prescription Required
Strength
Qty
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Rapamune is a medication used to prevent organ rejection in people who have received kidney transplants. It is indicated for patients who are 13 years of age or older.
Directions
Take Rapamune exactly as prescribed by your doctor.
Ingredients
The active ingredient in Rapamune is sirolimus.
Interactions
Tell your transplant team and pharmacist about all the medications you are taking. If you start a start medication without telling your healthcare providers, you may be at risk of transplant rejection.
Drug-drug interactions include:
Amiodarone
Apalutamide
Aprepitant
Atazanavir
Berotralstat
Bexarotene
Bosentan
Carbamazepine
Cenobamate
Ceritinib
Cimetidine
Clarithromycin
Cobicistat and cobicistat-containing coformulations
Conivaptan
Crizotinib
Cyclosporine
Dabrafenib
Darunavir
Dexamethasone
Diltiazem
Dronedarone
Duvelisib
Efavirenz
Enzalutamide
Erythromycin
Eslicarbazepine
Etravirine
Fedratinib
Fluconazole
Fosamprenavir
Fosaprepitant
Fosphenytoin
Grapefruit juice
Idelalisib
Imatinib
Indinavir
Isavuconazole (isavuconazonium sulfate)
Itraconazole
Ketoconazole
Lefamulin
Letermovir
Lonafarnib
Lopinavir
Lorlatinib
Lumacaftor
Mifepristone
Mitotane
Modafinil
Nafcillin
Nefazodone
Nelfinavir
Netupitant
Nilotinib
Ombitasvir-paritaprevir-ritonavir
Pexidartinib
Phenobarbital
Phenytoin
Posaconazole
Primidone
Ribociclib
Rifabutin
Rifampin (rifampicin)
Rifapentine
Ritonavir and ritonavir-containing coformulations
Saquinavir
Schisandra
St. John's wort
Telithromycin
Tucatinib
Verapamil
Voriconazole
Cautions
Sirolimus must be dosed carefully by trained healthcare professionals. Do not ever change the formulation that you are using without consulting your physician.
People who take Rapamune have an increased risk of infection and possible development of lymphoma.
You must have the drug level of Rapamune monitored while taking this drug.
Side Effects
Rapamune has many possible side effects, including:
Abdominal pain
Acne
Anemia
Arthralgia
Chest pain
Creatinine increase
Diarrhea
Dizziness
Fever
Headache
Hypercholesterolemia
Hypertension
Hypertriglyceridemia
Myalgia
Nasopharyngitis
Nausea
Pain
Peripheral edema
Stomatitis
Thrombocytopenia
Upper respiratory tract infection
Urinary tract infection
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IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Prescription Required
