What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

AirDuo (Fluticasone propionate and Salmeterol)


AirDuo (Fluticasone propionate and Salmeterol)

Prescription Required

55 / 14mcg (60doses / inhaler)
232 / 14mcg (60doses / inhaler)

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  • Product Details


    AirDuo RespiClick contains fluticasone propionate (corticosteroid) and salmeterol (long-acting beta2-adrenergic agonist (LABA)) for the treatment of asthma in people who are at least 12 years old.

    AirDuo RespiClick should not be used to relieve sudden breathing problems. AirDuo RespiClick is not a rescue inhaler and should not be used in the place of one.

    Fact Table




    US FDA


    Negligible oral

    Legal status


    Chemical Name


    Elimination half-life

    9–11 hours

    Dosage (Strength)

    55/14mcg, 232/14mcg (inhaler)


    Consult Doctor



    Protein binding

    96% - 99%

    PubChem CID






    ATC code






    Routes of administration



    AirDuo RespiClick contains a powder that should be inhaled by mouth. Follow the instructions that come with your prescription. 

    The inhalation powder comes in strengths of 55 mcg/14 mcg, 113 mcg/14 mcg, or 232 mcg/14 mcg of fluticasone propionate/salmeterol in each puff.

    Your starting dose will be based on previous asthma treatment and severity of asthma symptoms.

    The usual dose is one puff by mouth twice daily. A spacer or volume holder chamber should not be used with AirDuo RespiClick.


    The active ingredients in AirDuo RespiClick are fluticasone propionate and salmeterol xinafoate.


    AirDuo RespiClick should not be used for the primary treatment of status asthmaticus or acute episodes of asthma requiring intensive treatment.

    Discuss your allergies with your doctor before starting AirDuo RespiClick. AirDuo RespiClick should not be used if you have a severe allergy to milk proteins or any of the ingredients contained in AirDuo RespiClick.


    • Tell your doctor about all the medications you take including prescription, non-prescription, vitamins, supplements, and herbal supplements.
    • Using a LABA by itself to treat asthma can increase the risk of asthma-related death. It can also increase the risk of asthma-related hospitalization in pediatrics.
    • AirDuo RespiClick should not be used in patients during disease deterioration or life-threatening asthmatic episodes. AirDuo RespiClick should not be used for the relief of sudden symptoms of asthma.
    • AirDuo RespiClick should not be used with other LABAs due to the risk of overdose that can lead to serious cardiovascular effects or death.
    • AirDuo RespiClick can cause the development of a fungal infection of the mouth and pharynx. You should rinse your mouth with water after using AirDuo RespiClick.
    • Tell your doctor if you have a weak immune system. AirDuo RespiClick can worsen tuberculosis, bacterial, fungal, parasitic, and viral infections. 
    • Caution should be used if you are being switched from a systemic corticosteroid to AirDuo RespiClick. You should be slowly tapered from a systemic corticosteroid before switching to AirDuo RespiClick.
    • AirDuo RespiClick can cause hypercorticism and adrenal suppression. 
    • Stop using AirDuo RespiClick and seek medical care right away if you experience trouble breathing after using AirDuo RespiClick. Alternative treatment should be administered.
    • Tell your doctor if you have heart problems or central nervous system disorders. 
    • Tell your doctor if you have osteoporosis, a family history of osteoporosis, or if you are unable to move a lot.
    • Growth should be monitored in pediatric patients who use AirDuo RespiClick. 
    • AirDuo RespiClick can increase the risk of cataracts or glaucoma. Regular eye exams are recommended.
    • AirDuo RespiClick can cause eosinophilic conditions like Churg-Strauss Syndrome. 
    • Caution should be used if you have convulsive disorders, thyroid problems, diabetes mellitus, or ketoacidosis.
    • Tell your doctor if you experience:
      • Hypokalemia (low potassium levels in the blood): muscle cramps, muscle twitches, abnormal heart rhythms
      • high blood sugar
    • Tell your doctor if you are pregnant or plan to become pregnant.
    • Tell your doctor if you are breastfeeding or plan to breastfeed.

    Side Effects

    The most common side effects of AirDuo RespiClick are fungal infection of the mouth, common cold, cough, back pain, and headache.


    1. AirDuo RespiClick Prescribing Information. Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; 2021.
    2. AirDuo RespiClick (fluticasone propionate 113 mcg and salmeterol 14 mcg).. Accessed January 25, 2022. 
    3. Low Potassium Levels in Your Blood (Hypokalemia). Cleveland Clinic. Last reviewed March 12, 2018. Accessed January 31, 2022.

    Frequently Asked Questions about AirDuo

    What is AirDuo used for?

    AirDuo is an inhaled medication used to control long-term asthma symptoms in adults and adolescents aged 12 and older. It's not a quick-relief inhaler for sudden breathing problems.

    How does AirDuo work?

    It combines two medications: fluticasone propionate (steroid), which reduces inflammation in your airways, and salmeterol (long-acting bronchodilator), which helps them stay open.

    How often do I use AirDuo?

    Typically, it's taken twice a day, about 12 hours apart, as prescribed by your doctor. Always follow their instructions precisely.

    Does AirDuo have side effects?

    Like any medication, AirDuo can have side effects. Common ones include headache, muscle aches, thrush (mouth fungus), and sore throat. More serious side effects are rare, but consult your doctor if you experience chest pain, difficulty breathing, or irregular heartbeat.

    Can I use AirDuo with other medications?

    Tell your doctor about all medications and supplements you take, including over-the-counter ones, to avoid potential interactions.

    Is AirDuo safe for pregnant or breastfeeding women?

    There is limited data on the safety of AirDuo during pregnancy and breastfeeding. Discuss this with your doctor before using it if you are pregnant or breastfeeding.

    Does AirDuo work the same as Advair?

    AirDuo and Advair are similar medications containing the same two active ingredients. However, there may be slight differences in dosage, formulation, and cost. Discuss with your doctor which option is best for you.

    What should I do if I miss a dose?

    If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed one and continue with your regular schedule. Don't double up on doses.

    Is AirDuo addictive?

    While not physically addictive, some people with severe asthma may experience psychological dependence on AirDuo due to its ability to control symptoms. Discuss this with your doctor if you have concerns.

    How should I dispose of the used AirDuo inhaler?

    Follow your doctor's or pharmacist's instructions for safe disposal. Never litter or burn used inhalers.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13572

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