What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Restasis (Cyclosporine) Opthalmic Emulsion
Generic Equivalent - Restasis (Cyclosporine) Opthalmic Emulsion
Prescription Required
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Product Details
Description
RESTASIS (Cyclosporine) is an ophthalmic medication prescribed to treat certain conditions of the eye. RESTASIS (cyclosporine) treats keratoconjunctivitis sicca, which is when the eye produces fewer tears because of inflammation. During inflammation, the eye is swollen, red, and sometimes itchy and irritated. Inflammation may slow or stop tear production.
RESTASIS increases the production of tears, relieving dry eyes
RESTASIS contains an immunosuppressive agent, cyclosporine, that reduces inflammation. The exact mechanism is not well understood.
Directions
Instill one drop of RESTASIS twice daily into each eye.
Separate the administration of RESTASIS by at least 15 minutes from other ophthalmic products.
The vial should be gently inverted several times until the solution becomes a uniform, white, and opaque.
Ingredients
The active ingredient of RESTASIS is cyclosporine 0.05%.
The inactive ingredients are carbomer copolymer type A, castor oil, polysorbate 80, purified water, and sodium hydroxide.
Cautions
Do not touch the tip of RESTASIS to the eye or other surfaces. Doing so may contaminate the product and lead to infections of the eye.
Remove contact lenses before applying RESTASIS. Lenses should be reinserted at least 15 minutes after applying RESTASIS.
RESTASIS has not shown to increase tear production in patients taking topical anti-inflammatory drugs or those wearing punctal pugs.
Side Effects
The most common adverse effects of RESTASIS include:
- Blepharitis
- Blurred vision
- Burning sensation of eyes
- Conjunctival hyperemia
- Epiphora
- Eye discharge
- Eye irritation
- Eye pain
- Eye pruritus
- Feeling of a "foreign body" in the eye
- Headache
- Stinging of the eyes
- Urinary tract infection
- Visual disturbance
RESTASIS eye drops can be bought online with a valid prescription from a doctor.
References
- Restasis [package insert]. Irvine, CA: Allergan, 2012.
Fact Table
Formula
C62H111N11O12
License
EU EMA
Bioavailability
Varies
Legal status
RX Only
Chemical Name
Cyclosporine
Elimination half-life
Variable (about 24 hours)
Dosage (Strength)
0.4ml each (30 vials, 60 vials), 0.05% (5.5ml)
Pregnancy
Consult a doctor
Brands
Restasis
Protein binding
Greater than 95%
PubChem CID
5284373
MedlinePlus
a601207
ChEBI
4031
ATC code
L04AD01
DrugBank
DB00091
KEGG
D00184
Routes of administration
By mouth
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9592
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