Description
RESTASIS (Cyclosporine) is an ophthalmic medication prescribed to treat certain conditions of the eye. RESTASIS (cyclosporine) treats keratoconjunctivitis sicca, which is when the eye produces fewer tears because of inflammation. During inflammation, the eye is swollen, red, and sometimes itchy and irritated. Inflammation may slow or stop tear production.
RESTASIS increases the production of tears, relieving dry eyes
RESTASIS contains an immunosuppressive agent, cyclosporine, that reduces inflammation. The exact mechanism is not well understood.
Directions
Instill one drop of RESTASIS twice daily into each eye.
Separate the administration of RESTASIS by at least 15 minutes from other ophthalmic products.
The vial should be gently inverted several times until the solution becomes a uniform, white, and opaque.
Ingredients
The active ingredient of RESTASIS is cyclosporine 0.05%.
The inactive ingredients are carbomer copolymer type A, castor oil, polysorbate 80, purified water, and sodium hydroxide.
Cautions
Do not touch the tip of RESTASIS to the eye or other surfaces. Doing so may contaminate the product and lead to infections of the eye.
Remove contact lenses before applying RESTASIS. Lenses should be reinserted at least 15 minutes after applying RESTASIS.
RESTASIS has not shown to increase tear production in patients taking topical anti-inflammatory drugs or those wearing punctal pugs.
Side Effects
The most common adverse effects of RESTASIS include:
- Blepharitis
- Blurred vision
- Burning sensation of eyes
- Conjunctival hyperemia
- Epiphora
- Eye discharge
- Eye irritation
- Eye pain
- Eye pruritus
- Feeling of a "foreign body" in the eye
- Headache
- Stinging of the eyes
- Urinary tract infection
- Visual disturbance
RESTASIS eye drops can be bought online with a valid prescription from a doctor.
References
- Restasis [package insert]. Irvine, CA: Allergan, 2012.
Fact Table |
Formula |
C62H111N11O12 |
License |
EU EMA |
Bioavailability |
Varies |
Legal status |
RX Only |
Chemical Name |
Cyclosporine |
Elimination half-life |
Variable (about 24 hours) |
Dosage (Strength) |
0.4ml each (30 vials, 60 vials), 0.05% (5.5ml) |
Pregnancy |
Consult a doctor |
Brands |
Restasis |
Protein binding |
Greater than 95% |
PubChem CID |
5284373 |
MedlinePlus |
a601207 |
ChEBI |
4031 |
ATC code |
L04AD01 |
DrugBank |
DB00091 |
KEGG |
D00184 |
Routes of administration |
By mouth |
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 9592