What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Rowasa Enema (Mesalamine)

Also Known as Salofalk Enema


Rowasa Enema (Mesalamine)

Prescription Required

2g / 60ml
4g / 60ml

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Generic Equivalent - Rowasa Enema (Mesalamine)

Prescription Required


You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details


    Rowasa (mesalamine) is a rectal suspension enema used to treat adults who have mild to moderate distal ulcerative colitis, proctosigmoiditis, or proctitis. 

    Fact Table







    Legal status


    Chemical Name


    Elimination half-life

    5 hours

    Dosage (Strength)

    2g/60ml, 4g/60ml




    Rowasa Enema

    Protein binding


    PubChem CID






    ATC code






    Routes of administration



    Follow the instructions on the label of your prescription. Read the package insert that comes with your prescription. Talk to your doctor or pharmacist about any questions or concerns you may have.

    Rowasa Rectal Suspension Enema is available in disposable bottles that are wrapped in foil trays. 

    Insert one Rowasa enema rectally one time a day at bedtime. 

    Shake the bottle to ensure that the suspension is mixed thoroughly. Holding the neck of the bottle, take off the applicator tip's protective cover. It is recommended to lie on the left side with the left leg stretched out and the upper right leg flexed forward as this helps with balance. You may use the knee-chest position instead. 

    Gently insert the applicator tip into the rectum. The applicator tip should be pointed toward the navel. Squeeze the bottle steadily to ensure that most of the medication is delivered. Throw away the used bottle. 

    Stay in the same position for 30 minutes or longer. If possible, retain the enema all night. 

    Be sure to drink plenty of liquids during treatment.


    Each Rowasa Rectal Suspension Enema contains 4 grams of mesalamine in 60 mL aqueous suspension.

    The inactive ingredients include carbomer 934P, edetate disodium, potassium acetate, potassium metabisulfite, purified water, and xanthan gum. Sodium benzoate is used as a preservative. The applicator tip is protected by a cover that contains polyethylene and USP white petrolatum for lubrication. 


    Do not use Rowasa if you are allergic to salicylates, aminosalicylates, sulfites, or any other ingredient in Rowasa.


    • Before you use Rowasa enema, consult with your doctor:
      • About your allergies
      • About your medications
      • About your health problems
      • About your pregnancy or breastfeeding status
    • Rowasa can cause serious allergic reactions that can be fatal. Seek emergency care immediately if you have trouble breathing, swelling of the face, lips, mouth, or tongue, rash, or itchiness. 
    • Rowasa can cause kidney problems.
    • Rowasa can cause acute intolerance syndrome that is similar to the symptoms a flare up of inflammatory bowel disease, causing cramps, stomach pain, blood diarrhea, fever, headache, and rash. Contact your doctor right away if you experience any of these effects.
    • Rowasa can cause liver failure.
    • Rowasa can cause photosensitivity. It is recommended to avoid exposure to the sun, wear protective clothing, and apply a broad-spectrum when you go outside.
    • Rowasa can cause kidney stones.
    • Rowasa can cause lab abnormalities.
    • Rowasa can interact with certain medications, including non-steroidal anti-inflammatory drugs, azathioprine, and 6-mercaptopurine.

    Side Effects

    Call your doctor right away if you have side effects that bother you or won't go away. Rowasa can cause side effects such as stomach pain, cramps, headache, gas, nausea, flu, tiredness, fever, rash, cold, sore throat, diarrhea, leg pain, joint pain, dizziness, bloating, back pain, pain upon enema insertion, hemorrhoids, itching, rectal pain, constipation, hair loss, peripheral swelling, urinary tract infection, burning upon urination, lack of energy, and trouble sleeping.


    1. Rowasa (mesalamine) Rectal Suspension Enema 4.0 grams/unit (60 mL). Somerset, NJ: Meda Pharmaceuticals; 2020. 

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13125

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