What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Ryaltris Nasal Spray (Olopatadine/Mometasone)


Ryaltris Nasal Spray (Olopatadine/Mometasone)

Prescription Required

600mcg / 25mcg 240 Doses

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  • Product Details


    Ryaltris Nasal Spray contains an antihistamine, olopatadine hydrochloride, and a corticosteroid, mometasone furoate. This combination medication is used to alleviate the symptoms of seasonal allergies in adults and pediatrics who are at least 12 years old.

    Ryaltris comes in a bottle that provides metered-dose sprays; each spray delivers 665 mcg of olopatadine hydrochloride and 25 mcg of mometasone furoate.

    Ryaltris is only to be used nasally.

    Fact Table


    C21H23NO3 (Olopatadine), C27H30O6Cl2(Mometasone)


    US FDA, EU EMA, US DailyMed


    57%(Olopatadine), Less than 1% (Mometasone)

    Legal status


    Chemical Name


    Elimination half-life

    9 and 18 hours

    Dosage (Strength)

    600mcg / 25mcg 240 Doses


    Consult Doctor


    Ryaltris Nasal Spray

    Protein binding

    98% to 99%

    PubChem CID

    5281071 (Olopatadine), 441335 (Mometasone)


    a602025 (Olopatadine)


    6970 (Mometasone)

    ATC code



    DB00768(Olopatadine), DB00764(Mometasone)



    Routes of administration

    Nasal spray


    Carefully read the instructions that come with your Ryaltris prescription. Use as prescribed by your doctor. If you have any questions or concerns, tell your doctor or pharmacist.

    Shake the bottle well before you use Ryaltris.

    Before using Ryaltris for the first time, or if you have not used it in 14 days, prime the pump by aiming the tip away from your eyes and face and quickly and firmly pressing down on the pump six times until you see a fine mist.

    Your doctor will determine an appropriate Ryaltris Nasal Spray dosage for you. Patients generally use two sprays in each nostril twice a day.

    Before using Ryaltris, blow your nose gently to clear your nostrils. Next, close one nostril with your finger and insert the nasal tip into the other nostril, pointing it away from the nasal septum.

    Slightly tilt your head forward and quickly press down one time on the finger rests to activate the pump. Gently inhale through your nose as your spray, then exhale through your mouth.

    Keep your head tilted forward immediately after using it to prevent the medicine from going into your throat. Wait at least 15 minutes of using Ryaltris before you blow your nose.

    Use a clean dry tissue or cloth to clean the tip of the bottle.

    Put the dust cap on and store Ryaltris upright at room temperatures between 20°C and 25°C (68°F and 77°F). Do not put Ryaltris in the freezer or refrigerator.


    The active ingredients in Ryaltris Nasal Spray include olopatadine hydrochloride and mometasone furoate.

    Inactive ingredients include benzalkonium chloride, carboxymethylcellulose sodium, dibasic sodium phosphate heptahydrate, edetate disodium, hydrochloric acid, microcrystalline cellulose, polysorbate 80, sodium chloride, sodium hydroxide, and water for injection.


    Do not use Ryaltris if you are allergic to any of its ingredients.


    • Before you start using Ryaltris, talk to your doctor about:
      • All the prescription and nonprescription medications you use, including other nasal sprays and allergy products
      • Your allergies
      • Your current health conditions and past medical history
      • Your pregnancy status
      • Your breastfeeding status
    • Do not drive, operate machinery, or participate in other potentially hazardous activities until you know how Ryaltris affects you.
    • Ryaltris can cause nosebleeds, nasal ulceration, septal perforation, impaired wound healing of the nose, and local infections of the nose and pharynx.
    • Ryaltris can cause vision problems such as glaucoma and/or cataracts.
    • Ryaltris can suppress the immune system, which can increase the risk of infections or worsen infections.
    • Ryaltris can cause the body to have too much cortisol or prevent the adrenal glands from making enough cortisol, especially when using more than the recommended dose of Ryaltris.
    • Ryaltris can affect growth in pediatric patients; therefore, this medication should not be administered to pediatric patients who are younger than 12 years of age.

    Side Effects

    Common side effects of Ryaltris include unpleasant taste, nosebleeds, and nasal discomfort. Other side effects may also occur. Tell your doctor right away if you have side effects that bother you or won’t go away.


    Ryaltris. Columbus, OH: Hikma Specialty USA Inc.; 2022.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13867

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