What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Seasonique (levonorgestrel / ethinyl estradiol)

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Brand

Seasonique (levonorgestrel/ethinyl estradiol)

Prescription Required

Strength
Qty
0.15mg / 0.03mg / 0.01mg

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  • Product Details

    Description

    Your doctor may prescribe Seasonique for contraception, amenorrhea treatment, or to regulate your menstrual cycle. It contains both estrogen and progestin analogs.

    Seasonique is designed to prevent pregnancy by suppressing ovulation and thickening cervical mucus, making it harder for sperm to reach the egg.


    Fact Table

    Formula

    C21H28O2, C20H24O2

    License

    US DailyMed, US FDA, EU EMA

    Bioavailability

    38% - 48%

    Legal status

    Rx-Only

    Chemical Name

    Levonogestrel and Ethinyl Estradiol

    Elimination half-life

    7–36 hours

    Dosage (Strength)

    120mcg/30mcg

    Pregnancy

    -

    Brands

    Seasonique

    Protein binding

    97–98%

    PubChem CID

    13109, 5991

    MedlinePlus

    a610021, a604032

    ChEBI

    6443, 4903

    ATC code

    G03AC03, G03CA01

    DrugBank

    DB00367

    KEGG

    D00950, D00554

    Routes of administration

    By mouth

    Directions

    Take one tablet by mouth daily for 91 days as directed on the package. Seasonique contains 84 active pills followed by seven inactive pills.

    Take Seasonique at the same time every day to maximize its effectiveness.

    Ingredients

    The active ingredients in Seasonique are ethinyl estradiol and levonorgestrel.

    Interactions

    Many potential drug interactions with oral contraceptives can impact their effectiveness. Tell your doctor if you take any of the following:

    • Carbamazepine
    • Corticosteroids
    • Cyclosporine
    • Lamotrigine
    • Nelfinavir
    • Nevirapine
    • Phenobarbital
    • Phenytoin
    • Rifabutin
    • Rifampin
    • Ritonavir
    • St. John's Wort
    • Theophylline
    • Warfarin

    Cautions

    Seasonique should be used cautiously in women who smoke and are over 35 years of age or who have a history of a blood clot, heart attack, or stroke.

    Tell your healthcare provider about a history of heart disease, liver problems, or high blood pressure.

    Seasonique can increase the risk of metabolic problems like abnormal cholesterol and high blood sugar. Tell your doctor if you have a history of these problems.

    Report any abnormal bleeding to your doctor immediately.

    If you experience an increase in the magnitude or frequency of headaches while taking this drug, tell your doctor.

    Side Effects

    Common adverse reactions may include:

    • Abdominal pain
    • Acne
    • Anxiety
    • Appetite changes
    • Breast tenderness or pain
    • Changes in menstrual bleeding patterns
    • Changes in weight or appetite
    • Depression
    • Edema
    • Exacerbation of endometriosis or uterine fibroids
    • Gallbladder disease
    • Headache/migraine
    • Hypertension
    • Liver function disturbances
    • Nausea or vomiting
    • Rash
    • Seizures
    • Serious cardiovascular events
    • Sleep disturbances
    • Vaginal candidiasis or vaginitis
    • Visual changes

    References

    1. Seasonique [package insert]. Pomona, New York: Barr Pharmaceuticals; 2010.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 10061

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