What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Selzentry (Maraviroc)


Selzentry (Maraviroc)

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  • Product Details


    Selzentry is classified as a CCR5 co-receptor antagonist. Selzentry, when used with other antiretroviral medications, is used for treating CCR5-tropic HIV-1 infection in adults and pediatric patients who weigh at least 2 kilograms.

    Fact Table







    Legal status


    Chemical Name


    Elimination half-life

    14–18 hours

    Dosage (Strength)



    Consult Doctor



    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    The dosage forms of Selzentry include tablets and an oral solution. The tablets come in 25 mg, 75 mg, 150 mg, and 300 mg strengths. The oral solution has a concentration of 20 mg/mL.

    Once you are prescribed and buy Selzentry, the Selzentry is dosed twice daily by mouth and can be taken with or without food. Selzentry must be taken with other antiretroviral medications. 

    For pediatrics who weigh at least 2 kilograms, the dose should be given twice daily by mouth. The dose is based on body weight in kilograms and current antiretroviral medications. The dose should not be more than the recommended adult dose.


    The active ingredient in Selzentry tablets is Maraviroc

    Selzentry oral solution also contains 20 mg of maraviroc per mL.


    You should not take Selzentry if you have severe kidney problems or end-stage renal disease (ESRD) and are also taking potent CYP3A inhibitors or inducers.

    Warnings and Precautions


    See full prescribing information for complete boxed warnings.

    Hepatotoxicity has been reported which may be preceded by severe rash or other features of a systemic allergic reaction (e.g., fever, eosinophilia, or elevated IgE). 

    Immediately evaluate patients with signs or symptoms of hepatitis or allergic reaction.


    If you have severe kidney disease, you may not be able to take Selzentry if you use certain other medications. Tell your doctor about all other medications you use. Selzentry may cause serious liver problems. Stop taking this medicine and seek medical treatment at once if you have a serious drug reaction that can harm your liver. Symptoms may include: itching or rash, vomiting, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).

    Side Effects

    • You should discuss any allergies you may have with your doctor. Selzentry may contain ingredients that can cause an allergic reaction in those who are allergic to maraviroc or any of the ingredients in Selzentry.
    • Make sure you tell your doctor about any medications you take, including prescription, over-the-counter, vitamins, and herbal supplements as some medicines may interact with Selzentry.
    • Hepatotoxicity, or liver damage, with a severe rash or allergic reaction has been reported. Before starting Selzentry and at other times when clinically appropriate, labs including AST, ALT, and bilirubin should be obtained. If you develop a rash, an allergic reaction, or symptoms of hepatitis, hepatic laboratory parameters should be obtained and discontinuation of Selzentry should be considered.
    • Severe and potentially life-threatening skin and allergic reactions, including Stevens-Johnson syndrome, hypersensitivity reaction, and toxic epidermal necrolysis, have been reported. Immediately stop taking Selzentry and monitor closely if you develop a rash, fever, fatigue, muscles aches, blisters, eye inflammation, or facial swelling. Liver aminotransferases should also be monitored.
    • Tell your doctor if you have cardiovascular problems or if you have risk factors for cardiovascular problems. Cardiovascular events have been observed in patients taking Selzentry. 
    • If you have severe kidney problems or ESRD while taking Selzentry and you experience sudden drops in blood pressure when you stand from sitting or lying down, the dose should be decreased from 300 mg twice a day to 150 mg twice a day.
    • Tell your doctor if you are pregnant or plan to become pregnant. There is not enough data regarding the effects and safety of taking Selzentry while pregnant. There is a pregnancy registry that collects information and monitors the health of mom and baby while taking Selzentry during your pregnancy.
    • Tell your doctor if you breastfeed or plan to breastfeed. You should not breastfeed while taking Selzentry. You should also not breastfeed if you have HIV-1 because it can be passed to your baby through breastmilk. 

    If you experience any adverse effects while taking Selzentry (maraviroc), be sure to tell your doctor. Common Selzentry side effects include:

    • Abdominal pain
    • Cough
    • Dizziness
    • Fever
    • Rash
    • Upper respiratory tract infections


    SELZENTRY Prescribing Information. Research Triangle Park, NC: ViiV Healthcare, 2020.

    Frequently Asked Questions about Selzentry (Maraviroc)

    What is Selzentry (Maraviroc) used for?

    Selzentry is used in combination with other medicines to treat the infection caused by the human immunodeficiency virus (HIV).

    What are the available dosage forms of Selzentry?

    Selzentry is available in solution and tablet forms.

    Can children use Selzentry?

    Selzentry is not recommended for use in children younger than 2 years of age, preterm infants, or children weighing less than 2 kilograms.

    Is Selzentry safe during breastfeeding?

    There are no adequate studies determining the risk of using Selzentry during breastfeeding. Weigh the potential benefits against the risks before use.

    Are there any drug interactions with Selzentry?

    Selzentry may interact with various medicines, and it is crucial to inform your healthcare professional about all medications you are taking.

    Should Selzentry be used with caution in certain medical conditions?

    Caution is advised when using Selzentry in patients with heart disease, liver problems, postural hypotension, kidney disease, or severe kidney disease requiring dialysis.

    How should Selzentry be taken?

    Follow the medication guide and your doctor’s instructions. Take it with other HIV medicines, do not miss doses, and do not stop taking it without consulting your doctor. It can be taken with or without food.

    What is the recommended dosage of Selzentry?

    The dosage varies and should be as prescribed by your doctor. For adults, it's typically 150, 300, or 600 mg twice a day. For children 2 years and older, the dose is based on body weight.

    What should be done if a dose is missed?

    If a dose is missed, take it as soon as possible unless the next dose is less than 6 hours away. Do not double the dose.

    How should Selzentry be stored?

    Store it at room temperature away from heat, moisture, and light. Keep out of reach of children and dispose of unused medicine properly.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 9620

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