What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Sitavig (Acyclovir)
Prescription Required
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Product Details
Description
Sitavig is a prescription antiviral medication used for the treatment of cold sores. Cold sores are another term for "oral herpes," a long-term infection of the mouth with the herpes simplex virus. Symptoms can include soreness, burning sensation, redness, ulcers, rashes, blisters, and tingling.
Symptoms of oral herpes usually go away on their own but in some cases, may need treatment. Sitavig is an antiviral that works by incorporating into viral DNA to prevent the replication of viral particles. By preventing replication, the virus does not spread to healthy tissue, and symptoms will resolve more quickly.
Sitavig will not cure oral herpes but treats the symptoms. Oral herpes is a long-term infection that is kept suppressed by the immune system.
Fact Table
Formula
C8H11N5O3
License
US FDA
Bioavailability
15–20%
Legal status
Rx-only
Chemical Name
Aciclovir
Elimination half-life
2–4 hours
Dosage (Strength)
50mg
Pregnancy
No Known Risk
Brands
Sitavig, Zovirax
Protein binding
9–33%
PubChem CID
2022
MedlinePlus
a681045
ChEBI
2453
ATC code
R03AC18
DrugBank
DB00787
KEGG
D00222
Routes of administration
By mouth
Directions
At the onset of symptoms, insert one 50 mg buccal tablet into the region between the upper gums and the lips. Leave the buccal tablet in place and do not suck, chew, crush, or swallow the tablet.
Leave Sitavig in place until it dissolves.
You may gently rinse your mouth with water while the buccal tablet is in place to clean the teeth.
Ingredients
The active ingredient in Sitavig is acyclovir.
Interactions
Tell your doctor and pharmacist if you are using the following before you start Sitavig:
- Talimogene Laherparepvec
Cautions
Tell your doctor if you are pregnant or planning to become pregnant before starting Sitavig.
Use caution if you have a known allergy to milk or milk products.
Side Effects
The most common adverse reactions can include:
- Anaphylaxis
- Angioedema
- Aphthous stomatitis
- Application site irritation
- Burning skin
- Contact dermatitis
- Cracked lips
- Desquamation
- Dry lips
- Dryness of skin
- Eczema
- Erythema
- Flakiness of skin
- Gingival pain
- Lethargy
- Local pain
- Localized edema
- Pruritus
- Skin rash
- Stinging on skin
- Transient burning
References
Sitavig. Charleston, SC: EPI Health LLC; 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13626
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